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ONTOLOGY REPORT - ANNOTATIONS


Term:progesterone metabolic process
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Accession:GO:0042448 term browser browse the term
Definition:The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
Synonyms:exact_synonym: progesterone metabolism



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progesterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2388722 (MGI:2388413|PMID:12297623)
Ensembl
RGD
PMID:12297623 GO_REF:0000107 MGI:2388413 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 involved_in IBA
ISO
PMID:21873635
(PMID:21232532)
RGD PMID:21232532 PMID:21873635 RGD:13792537 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c14 aldo-keto reductase family 1, member C14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:66,156,286...66,173,277
Ensembl chr17:66,156,288...66,173,277
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 involved_in IBA
ISO
PMID:21873635
(PMID:21232532)
RGD PMID:21232532 PMID:21873635 RGD:13792537 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 acts_upstream_of_or_within
involved_in
IDA
IBA
ISO
PMID:8172618
PMID:21873635
(PMID:21232532)
RGD PMID:21232532 PMID:4392955 PMID:8172618 PMID:21873635 RGD:2303525, RGD:1299435, RGD:13792537 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G AKR1C3l1 aldo-keto reductase family 1 member C3-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:22266943)
UniProt
Ensembl
RGD
PMID:22266943 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 IDA RGD PMID:19665544 RGD:4891164 NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,023,767...4,026,923
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:10620362) RGD PMID:10620362 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in ISO (PMID:14640697) RGD PMID:14640697 NCBI chr 6:127,243,315...127,274,765
Ensembl chr 6:127,243,315...127,274,760
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in ISO (PMID:11294878) RGD PMID:11294878 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 IDA RGD PMID:4392955 RGD:2303525 NCBI chr 2:186,008,944...186,028,417
Ensembl chr 2:186,008,943...186,020,393
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:9202401 RGD:4892033 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:103036 (MGI:3526508|PMID:15471942)
Ensembl
RGD
PMID:15471942 GO_REF:0000107 MGI:3526508 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) RGD PMID:24530842 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:20133449 RGD:10059648 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IDA RGD PMID:1955079 RGD:1625116 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:1703300) RGD PMID:1703300 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 acts_upstream_of_or_within ISO MGI:3042568 (MGI:3039987|PMID:14963026) RGD PMID:14963026 MGI:3039987 NCBI chr10:83,357,329...83,379,873
Ensembl chr10:83,357,359...83,550,976
JBrowse link
progesterone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 acts_upstream_of_or_within ISO MGI:3527218 (MGI:3526508|PMID:15471942) RGD PMID:15471942 MGI:3526508 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131
JBrowse link
G Egr1 early growth response 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:82584|PMID:8703054)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:8703054 GO_REF:0000024 GO_REF:0000107 MGI:82584 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:23045399 RGD:26884342 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
G Mir455 microRNA 455 IDA RGD PMID:23045399 RGD:26884342 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      small molecule metabolic process 1829
        cellular ketone metabolic process 235
          progesterone metabolic process 23
            progesterone biosynthetic process + 9
            progesterone catabolic process 1
Path 2
Term Annotations click to browse term
  biological_process 19834
    biological regulation 13775
      regulation of biological quality 4234
        regulation of hormone levels 627
          hormone metabolic process 241
            cellular hormone metabolic process 147
              C21-steroid hormone metabolic process 46
                progesterone metabolic process 23
                  progesterone biosynthetic process + 9
                  progesterone catabolic process 1
paths to the root