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ONTOLOGY REPORT - ANNOTATIONS


Term:progesterone metabolic process
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Accession:GO:0042448 term browser browse the term
Definition:The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
Synonyms:exact_synonym: progesterone metabolism


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progesterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2388722 (MGI:2388413|PMID:12297623)
Ensembl
RGD
PMID:12297623 GO_REF:0000107 MGI:2388413 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akr1c14 aldo-keto reductase family 1, member C14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:69,806,095...69,827,125
Ensembl chr17:69,806,065...69,827,112
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 involved_in IBA
ISO
PMID:21873635
(PMID:21232532)
RGD PMID:21232532, PMID:21873635 RGD:13792537 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in IDA
IBA
ISO
PMID:21873635
(PMID:21232532)
RGD PMID:21232532, PMID:4392955, PMID:21873635 RGD:2303525, RGD:13792537 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:22266943)
UniProt
Ensembl
RGD
PMID:22266943, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 IDA RGD PMID:19665544 RGD:4891164 NCBI chr20:4,486,213...4,489,358
Ensembl chr20:4,486,219...4,489,550
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 involved_in ISO (PMID:10620362) RGD PMID:10620362 NCBI chr12:10,636,294...10,684,273
Ensembl chr12:10,636,275...10,684,278
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in ISO (PMID:14640697) RGD PMID:14640697 NCBI chr 6:132,242,328...132,273,788
Ensembl chr 6:132,242,328...132,273,787
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in ISO (PMID:11294878) RGD PMID:11294878 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325
JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 IDA RGD PMID:4392955 RGD:2303525 NCBI chr 2:200,615,910...200,633,317
Ensembl chr 2:200,584,986...200,692,335
JBrowse link
G RGD1564865 similar to 20-alpha-hydroxysteroid dehydrogenase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:69,468,427...69,497,132
Ensembl chr17:69,468,427...69,497,132
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:9202401 RGD:4892033 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:103036 (MGI:3526508|PMID:15471942)
Ensembl
RGD
PMID:15471942 GO_REF:0000107 MGI:3526508 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:20133449 RGD:10059648 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IDA RGD PMID:1955079 RGD:1625116
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:1703300) RGD PMID:1703300 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 acts_upstream_of_or_within ISO MGI:3042568 (MGI:3039987|PMID:14963026) RGD PMID:14963026 MGI:3039987 NCBI chr10:86,313,430...86,335,868
Ensembl chr10:86,313,383...86,335,923
JBrowse link
progesterone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 acts_upstream_of_or_within ISO MGI:3527218 (MGI:3526508|PMID:15471942) RGD PMID:15471942 MGI:3526508 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:2,069,409...2,083,370
Ensembl chr14:2,069,409...2,083,370
JBrowse link
G Egr1 early growth response 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:82584|PMID:8703054)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:8703054 GO_REF:0000024 GO_REF:0000107 MGI:82584 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:23045399 RGD:26884342 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
JBrowse link
G Mir455 microRNA 455 IDA RGD PMID:23045399 RGD:26884342 NCBI chr 5:79,097,208...79,097,285
Ensembl chr 5:79,097,208...79,097,285
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      small molecule metabolic process 1784
        cellular ketone metabolic process 228
          progesterone metabolic process 22
            progesterone biosynthetic process + 8
            progesterone catabolic process 1
Path 2
Term Annotations click to browse term
  biological_process 19599
    biological regulation 13561
      regulation of biological quality 4167
        regulation of hormone levels 606
          hormone metabolic process 232
            cellular hormone metabolic process 142
              C21-steroid hormone metabolic process 44
                progesterone metabolic process 22
                  progesterone biosynthetic process + 8
                  progesterone catabolic process 1
paths to the root