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ONTOLOGY REPORT - ANNOTATIONS


Term:pigment metabolic process
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Accession:GO:0042440 term browser browse the term
Definition:The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.
Synonyms:exact_synonym: pigment metabolism


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carotenoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppox protoporphyrinogen oxidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624794:212,220...215,891
Ensembl chrNW_004624794:212,226...215,931
JBrowse link
flavone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha ISO hesperetin RGD PMID:22767158 RGD:7242166 NCBI chrNW_004624755:7,826,219...8,460,746
Ensembl chrNW_004624755:8,375,596...8,465,297
JBrowse link
heme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:21,698,689...21,709,907
Ensembl chrNW_004624760:21,698,587...21,711,822
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 involved_in ISO (MGI:6490396|PMID:33307066) MGI PMID:33307066 MGI:6490396 NCBI chrNW_004624730:5,984,764...5,998,929
Ensembl chrNW_004624730:5,984,766...6,001,667
JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624789:11,435,955...11,448,867
Ensembl chrNW_004624789:11,435,779...11,448,984
JBrowse link
G Fech ferrochelatase involved_in ISO (MGI:3622942|PMID:15677551) MGI PMID:15677551 MGI:3622942 NCBI chrNW_004624792:3,067,270...3,101,698
Ensembl chrNW_004624792:3,064,841...3,102,345
JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in ISO (MGI:79058|PMID:8563760) MGI PMID:8563760 MGI:79058 NCBI chrNW_004624784:14,467,515...14,474,954
Ensembl chrNW_004624784:14,467,533...14,474,954
JBrowse link
G LOC101715399 cytochrome c oxidase assembly protein COX15 homolog involved_in IEA Ensembl
InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624737:11,435,006...11,452,934
Ensembl chrNW_004624737:11,435,074...11,453,727
JBrowse link
G LOC101726271 protoheme IX farnesyltransferase, mitochondrial acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3640032|PMID:16782876)
(MGI:3604933|PMID:16103131)
MGI
Ensembl
TreeGrafter
PMID:16103131 PMID:16782876 GO_REF:0000107 GO_REF:0000118 MGI:3604933 MGI:3640032 NCBI chrNW_004624877:2,161,819...2,282,336
Ensembl chrNW_004624877:2,161,885...2,282,615
JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:212,220...215,891
Ensembl chrNW_004624794:212,226...215,931
JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624906:910,306...914,898
Ensembl chrNW_004624906:910,313...914,898
JBrowse link
G Uros uroporphyrinogen III synthase involved_in ISO (MGI:3776218|PMID:16532394) MGI PMID:16532394 MGI:3776218 NCBI chrNW_004624737:21,340,193...21,383,452 JBrowse link
heme B biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 (LAN blood group) NOT|involved_in ISO (PMID:22655043) UniProt PMID:22655043 NCBI chrNW_004624823:5,797,897...5,805,055
Ensembl chrNW_004624823:5,797,943...5,808,448
JBrowse link
G Alad aminolevulinate dehydratase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:21,698,689...21,709,907
Ensembl chrNW_004624760:21,698,587...21,711,822
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 involved_in ISO (MGI:6490396|PMID:33307066) MGI PMID:33307066 MGI:6490396 NCBI chrNW_004624730:5,984,764...5,998,929
Ensembl chrNW_004624730:5,984,766...6,001,667
JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624789:11,435,955...11,448,867
Ensembl chrNW_004624789:11,435,779...11,448,984
JBrowse link
G Fech ferrochelatase involved_in ISO (MGI:3622942|PMID:15677551) MGI PMID:15677551 MGI:3622942 NCBI chrNW_004624792:3,067,270...3,101,698
Ensembl chrNW_004624792:3,064,841...3,102,345
JBrowse link
G Flvcr1 FLVCR choline and heme transporter 1 involved_in ISO (MGI:5471193|PMID:23187127) MGI PMID:23187127 MGI:5471193 NCBI chrNW_004624771:18,239,437...18,270,408 JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in ISO (MGI:79058|PMID:8563760) MGI PMID:8563760 MGI:79058 NCBI chrNW_004624784:14,467,515...14,474,954
Ensembl chrNW_004624784:14,467,533...14,474,954
JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:212,220...215,891
Ensembl chrNW_004624794:212,226...215,931
JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624906:910,306...914,898
Ensembl chrNW_004624906:910,313...914,898
JBrowse link
G Uros uroporphyrinogen III synthase involved_in ISO (MGI:3776218|PMID:16532394) MGI PMID:16532394 MGI:3776218 NCBI chrNW_004624737:21,340,193...21,383,452 JBrowse link
heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb10 ATP binding cassette subfamily B member 10 involved_in ISO (MGI:5648801|PMID:24421385) UniProt PMID:24421385 MGI:5648801 NCBI chrNW_004624775:19,546,002...19,579,767
Ensembl chrNW_004624775:19,546,192...19,578,728
JBrowse link
G Alad aminolevulinate dehydratase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:53493|PMID:4959158), (MGI:53609|PMID:4981581), (MGI:63121|PMID:14050799) MGI
Ensembl
UniProt
TreeGrafter
RGD
PMID:1764448 PMID:4959158 PMID:4981581 PMID:14050799 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 MGI:53493 MGI:53609 MGI:63121 RGD:1599020 NCBI chrNW_004624760:21,698,689...21,709,907
Ensembl chrNW_004624760:21,698,587...21,711,822
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 involved_in IEA TreeGrafter
UniProt
GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004624730:5,984,764...5,998,929
Ensembl chrNW_004624730:5,984,766...6,001,667
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 involved_in IEA TreeGrafter
Ensembl
UniProt
GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624910:426,273...726,778
Ensembl chrNW_004624910:426,032...448,325
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (MGI:5447588|PMID:23135403)
(PMID:23135403)
UniProt PMID:23135403 MGI:5447588 NCBI chrNW_004624764:12,068,518...12,070,542
Ensembl chrNW_004624764:12,068,638...12,072,190
JBrowse link
G Cpox coproporphyrinogen oxidase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:77569|PMID:8407975) MGI
UniProt
Ensembl
RGD
PMID:3955059 PMID:8407975 GO_REF:0000107 GO_REF:0000117 MGI:77569 RGD:1600961 NCBI chrNW_004624789:11,435,955...11,448,867
Ensembl chrNW_004624789:11,435,779...11,448,984
JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1327758|PMID:9989256)
(MGI:3794459|PMID:16306232)
(MGI:3620268|PMID:16503645), (MGI:3696634|PMID:15496139)
(MGI:79136|PMID:8611576)
MGI
UniProt
InterPro
RGD
TreeGrafter
PMID:3955059 PMID:8611576 PMID:9989256 PMID:15496139 PMID:16306232 More... GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 MGI:1327758 MGI:3620268 MGI:3696634 MGI:3794459 MGI:79136 RGD:1600961 NCBI chrNW_004624792:3,067,270...3,101,698
Ensembl chrNW_004624792:3,064,841...3,102,345
JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624784:14,467,515...14,474,954
Ensembl chrNW_004624784:14,467,533...14,474,954
JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within ISO (MGI:1352605|PMID:10617683) MGI PMID:10617683 MGI:1352605 NCBI chrNW_004624747:12,717,713...12,746,040
Ensembl chrNW_004624747:12,717,707...12,746,724
JBrowse link
G LOC101726271 protoheme IX farnesyltransferase, mitochondrial involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000043 NCBI chrNW_004624877:2,161,819...2,282,336
Ensembl chrNW_004624877:2,161,885...2,282,615
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624895:3,265,326...3,273,531
Ensembl chrNW_004624895:3,264,798...3,273,529
JBrowse link
G Ppox protoporphyrinogen oxidase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3687447|PMID:3346226) MGI
UniProt
Ensembl
RGD
PMID:3346226 PMID:3955059 GO_REF:0000043 GO_REF:0000107 MGI:3687447 RGD:1600961 NCBI chrNW_004624794:212,220...215,891
Ensembl chrNW_004624794:212,226...215,931
JBrowse link
G Slc11a2 solute carrier family 11 member 2 acts_upstream_of_or_within ISO (MGI:3691553|PMID:11739192) MGI PMID:11739192 MGI:3691553 NCBI chrNW_004624816:1,345,020...1,389,615
Ensembl chrNW_004624816:1,345,006...1,384,299
JBrowse link
G Slc25a39 solute carrier family 25 member 39 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624795:717,158...720,626
Ensembl chrNW_004624795:717,154...723,125
JBrowse link
G Tmem14c transmembrane protein 14C involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624756:15,179,801...15,187,475 JBrowse link
G Urod uroporphyrinogen decarboxylase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3703836|PMID:17360334) MGI
UniProt
Ensembl
PMID:17360334 GO_REF:0000043 GO_REF:0000107 MGI:3703836 NCBI chrNW_004624906:910,306...914,898
Ensembl chrNW_004624906:910,313...914,898
JBrowse link
G Uros uroporphyrinogen III synthase involved_in ISO (PMID:3805019) UniProt PMID:3805019 NCBI chrNW_004624737:21,340,193...21,383,452 JBrowse link
heme catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blvra biliverdin reductase A involved_in IEA UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chrNW_004624740:17,462,201...17,505,725
Ensembl chrNW_004624740:17,462,537...17,478,269
JBrowse link
G Blvrb biliverdin reductase B involved_in ISO (PMID:10858451), (PMID:7929092) UniProt PMID:7929092 PMID:10858451 NCBI chrNW_004624925:432,137...452,946
Ensembl chrNW_004624925:432,137...452,903
JBrowse link
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6383783|PMID:31571584) RGD
MGI
TreeGrafter
PMID:15226268 PMID:31571584 GO_REF:0000118 MGI:6383783 RGD:1547877 NCBI chrNW_004624750:341,699...346,005
Ensembl chrNW_004624750:342,146...345,887
JBrowse link
G Hmox2 heme oxygenase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624824:2,272,515...2,317,115 JBrowse link
heme metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 (LAN blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624823:5,797,897...5,805,055
Ensembl chrNW_004624823:5,797,943...5,808,448
JBrowse link
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within ISO (MGI:3607883|PMID:16183037) MGI PMID:16183037 MGI:3607883 NCBI chrNW_004624750:341,699...346,005
Ensembl chrNW_004624750:342,146...345,887
JBrowse link
G Hpx hemopexin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3799398|PMID:18556779) MGI
Ensembl
PMID:18556779 GO_REF:0000107 MGI:3799398 NCBI chrNW_004624817:7,947,554...7,957,553
Ensembl chrNW_004624817:7,947,639...7,957,462
JBrowse link
G Slc48a1 solute carrier family 48 member 1 involved_in ISO (MGI:6383783|PMID:31571584) MGI PMID:31571584 MGI:6383783 NCBI chrNW_004624816:4,476,502...4,496,641
Ensembl chrNW_004624816:4,476,491...4,485,030
JBrowse link
G Urod uroporphyrinogen decarboxylase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1929011|PMID:11134514) MGI
Ensembl
PMID:11134514 GO_REF:0000107 MGI:1929011 NCBI chrNW_004624906:910,306...914,898
Ensembl chrNW_004624906:910,313...914,898
JBrowse link
heme O biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:21,698,689...21,709,907
Ensembl chrNW_004624760:21,698,587...21,711,822
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 involved_in ISO (MGI:6490396|PMID:33307066) MGI PMID:33307066 MGI:6490396 NCBI chrNW_004624730:5,984,764...5,998,929
Ensembl chrNW_004624730:5,984,766...6,001,667
JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624789:11,435,955...11,448,867
Ensembl chrNW_004624789:11,435,779...11,448,984
JBrowse link
G Fech ferrochelatase involved_in ISO (MGI:3622942|PMID:15677551) MGI PMID:15677551 MGI:3622942 NCBI chrNW_004624792:3,067,270...3,101,698
Ensembl chrNW_004624792:3,064,841...3,102,345
JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in ISO (MGI:79058|PMID:8563760) MGI PMID:8563760 MGI:79058 NCBI chrNW_004624784:14,467,515...14,474,954
Ensembl chrNW_004624784:14,467,533...14,474,954
JBrowse link
G LOC101726271 protoheme IX farnesyltransferase, mitochondrial involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624877:2,161,819...2,282,336
Ensembl chrNW_004624877:2,161,885...2,282,615
JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:212,220...215,891
Ensembl chrNW_004624794:212,226...215,931
JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624906:910,306...914,898
Ensembl chrNW_004624906:910,313...914,898
JBrowse link
G Uros uroporphyrinogen III synthase involved_in ISO (MGI:3776218|PMID:16532394) MGI PMID:16532394 MGI:3776218 NCBI chrNW_004624737:21,340,193...21,383,452 JBrowse link
heme oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 involved_in IEA TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624750:341,699...346,005
Ensembl chrNW_004624750:342,146...345,887
JBrowse link
G Hmox2 heme oxygenase 2 involved_in IEA TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624824:2,272,515...2,317,115 JBrowse link
melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asip agouti signaling protein acts_upstream_of_or_within ISO (MGI:76308|PMID:7665913) MGI PMID:7665913 MGI:76308 NCBI chrNW_004624842:5,079,499...5,084,933
Ensembl chrNW_004624842:5,079,499...5,084,933
JBrowse link
G Cited1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 involved_in ISO (MGI:4412464|PMID:11434569) UniProt PMID:11434569 MGI:4412464 NCBI chrNW_004624903:2,596,049...2,601,315 JBrowse link
G Dct dopachrome tautomerase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:76308|PMID:7665913) MGI
UniProt
PMID:7665913 GO_REF:0000043 MGI:76308 NCBI chrNW_004624879:1,241,593...1,346,765
Ensembl chrNW_004624879:1,241,910...1,279,444
JBrowse link
G Ddt D-dopachrome tautomerase involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624747:12,473,181...12,474,898 JBrowse link
G Mc1r melanocortin 1 receptor acts_upstream_of_or_within ISO (MGI:76308|PMID:7665913) MGI PMID:7665913 MGI:76308 NCBI chrNW_004624746:131,356...137,745
Ensembl chrNW_004624746:132,904...133,860
JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO (MGI:76308|PMID:7665913) MGI PMID:7665913 MGI:76308 NCBI chrNW_004624731:8,114,557...8,280,586
Ensembl chrNW_004624731:8,113,715...8,280,823
JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1202196|PMID:9548375), (MGI:76308|PMID:7665913) MGI
TreeGrafter
PMID:7665913 PMID:9548375 GO_REF:0000118 MGI:1202196 MGI:76308 NCBI chrNW_004624896:2,163,043...2,432,016
Ensembl chrNW_004624896:2,163,468...2,415,432
JBrowse link
G Pmel premelanosome protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:76308|PMID:7665913) MGI
Ensembl
PMID:7665913 GO_REF:0000107 MGI:76308 NCBI chrNW_004624802:12,073,932...12,092,885
Ensembl chrNW_004624802:12,083,090...12,092,767
JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of ISO (MGI:3775882|PMID:18166528) MGI PMID:18166528 MGI:3775882 NCBI chrNW_004624731:11,552,865...11,573,987
Ensembl chrNW_004624731:11,552,969...11,574,044
JBrowse link
G Trpc1 transient receptor potential cation channel subfamily C member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:19,307,346...19,375,537 JBrowse link
G Tyr tyrosinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1202196|PMID:9548375)
(MGI:76308|PMID:7665913)
MGI
Ensembl
UniProt
TreeGrafter
PMID:7665913 PMID:9548375 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 MGI:1202196 MGI:76308 NCBI chrNW_004624845:844,492...933,098
Ensembl chrNW_004624845:844,293...933,098
JBrowse link
G Tyrp1 tyrosinase related protein 1 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624736:17,011,092...17,028,689
Ensembl chrNW_004624736:17,011,115...17,029,322
JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624879:1,241,593...1,346,765
Ensembl chrNW_004624879:1,241,910...1,279,444
JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO (PMID:25513726), (PMID:32966160) UniProt PMID:25513726 PMID:32966160 NCBI chrNW_004624896:2,163,043...2,432,016
Ensembl chrNW_004624896:2,163,468...2,415,432
JBrowse link
G Slc45a2 solute carrier family 45 member 2 involved_in ISO (PMID:32966160)
(MGI:7338895|PMID:35469906)
UniProt PMID:32966160 PMID:35469906 MGI:7338895 NCBI chrNW_004624759:20,640,407...20,701,790
Ensembl chrNW_004624759:20,673,033...20,701,361
JBrowse link
melanin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2 apoptosis regulator acts_upstream_of_or_within ISO (MGI:2154874|PMID:11709185) MGI PMID:11709185 MGI:2154874 NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344
JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO (MGI:1202196|PMID:9548375) MGI PMID:9548375 MGI:1202196 NCBI chrNW_004624731:8,114,557...8,280,586
Ensembl chrNW_004624731:8,113,715...8,280,823
JBrowse link
G Tyrp1 tyrosinase related protein 1 acts_upstream_of_or_within ISO (MGI:1202196|PMID:9548375) MGI PMID:9548375 MGI:1202196 NCBI chrNW_004624736:17,011,092...17,028,689
Ensembl chrNW_004624736:17,011,115...17,029,322
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO (MGI:5429122|PMID:22627278) MGI PMID:22627278 MGI:5429122 NCBI chrNW_004624731:5,350,912...5,359,286 JBrowse link
negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (MGI:5912387|PMID:29025994) CACAO PMID:29025994 MGI:5912387 NCBI chrNW_004624828:6,255,889...6,268,697
Ensembl chrNW_004624828:6,259,618...6,268,272
JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:31097585) UniProt PMID:31097585 NCBI chrNW_004624771:11,943,894...11,991,477
Ensembl chrNW_004624771:11,943,914...11,991,411
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO (MGI:5499726|PMID:16272156) UniProt PMID:16272156 MGI:5499726 NCBI chrNW_004624848:3,968,845...4,184,740
Ensembl chrNW_004624848:3,968,362...4,182,885
JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of_or_within ISO (MGI:3775882|PMID:18166528) MGI PMID:18166528 MGI:3775882 NCBI chrNW_004624731:11,552,865...11,573,987
Ensembl chrNW_004624731:11,552,969...11,574,044
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (MGI:5619434|PMID:23569434) CACAO PMID:23569434 MGI:5619434 NCBI chrNW_004624822:1,824,378...1,843,599
Ensembl chrNW_004624822:1,825,238...1,841,288
JBrowse link
pigment biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (MGI:2181477|PMID:12036291) MGI PMID:12036291 MGI:2181477 NCBI chrNW_004624730:59,570,879...59,573,001
Ensembl chrNW_004624730:59,570,915...59,571,871
JBrowse link
pigment metabolic process involved in pigmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (PMID:33208952)
(MGI:6492453|PMID:33208952)
(PMID:31117290)
UniProt PMID:31117290 PMID:33208952 MGI:6492453 NCBI chrNW_004624828:6,255,889...6,268,697
Ensembl chrNW_004624828:6,259,618...6,268,272
JBrowse link
G Tbx2 T-box transcription factor 2 acts_upstream_of_negative_effect ISO (MGI:6814712|PMID:26971330) UniProt PMID:26971330 MGI:6814712 NCBI chrNW_004624871:2,428,757...2,437,447
Ensembl chrNW_004624871:2,429,407...2,437,447
JBrowse link
positive regulation of heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624836:5,605,901...5,769,488
Ensembl chrNW_004624836:5,605,831...5,766,275
JBrowse link
G Slc6a9 solute carrier family 6 member 9 involved_in ISO (MGI:6450351|PMID:28495915) ARUK-UCL PMID:28495915 MGI:6450351 NCBI chrNW_004624892:3,275,034...3,308,579
Ensembl chrNW_004624892:3,275,034...3,305,692
JBrowse link
positive regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:21291857) UniProt PMID:21291857 NCBI chrNW_004624822:31,175...74,252
Ensembl chrNW_004624822:33,880...74,308
JBrowse link
G Asip agouti signaling protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624842:5,079,499...5,084,933
Ensembl chrNW_004624842:5,079,499...5,084,933
JBrowse link
G Atp7a ATPase copper transporting alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624836:2,804,349...3,058,125
Ensembl chrNW_004624836:2,808,681...2,993,452
JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:23334344) UniProt PMID:23334344 NCBI chrNW_004624746:17,616,296...17,659,021
Ensembl chrNW_004624746:17,616,940...17,658,548
JBrowse link
G LOC101713959 PDZ domain-containing protein GIPC1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624901:1,605,561...1,620,376
Ensembl chrNW_004624901:1,604,420...1,615,460
Ensembl chrNW_004624901:1,604,420...1,615,460
JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:28842328) UniProt PMID:28842328 NCBI chrNW_004624771:11,943,894...11,991,477
Ensembl chrNW_004624771:11,943,914...11,991,411
JBrowse link
G Pmel premelanosome protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624802:12,073,932...12,092,885
Ensembl chrNW_004624802:12,083,090...12,092,767
JBrowse link
G Rab38 RAB38, member RAS oncogene family ISO RGD PMID:17043139 RGD:152025192 NCBI chrNW_004624845:1,908,410...1,983,897
Ensembl chrNW_004624845:1,906,671...1,984,029
JBrowse link
G Tyrp1 tyrosinase related protein 1 involved_in ISO (MGI:5294257|PMID:21949658)
(PMID:21996312)
CACAO PMID:21949658 PMID:21996312 MGI:5294257 NCBI chrNW_004624736:17,011,092...17,028,689
Ensembl chrNW_004624736:17,011,115...17,029,322
JBrowse link
protoporphyrinogen IX biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase involved_in IEA UniProt GO_REF:0000041 NCBI chrNW_004624760:21,698,689...21,709,907
Ensembl chrNW_004624760:21,698,587...21,711,822
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 involved_in IEA UniProt GO_REF:0000041 GO_REF:0000104 NCBI chrNW_004624730:5,984,764...5,998,929
Ensembl chrNW_004624730:5,984,766...6,001,667
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 involved_in IEA UniProt GO_REF:0000041 GO_REF:0000104 NCBI chrNW_004624910:426,273...726,778
Ensembl chrNW_004624910:426,032...448,325
JBrowse link
G Cpox coproporphyrinogen oxidase involved_in ISO
IEA
RGD
UniProt
TreeGrafter
PMID:3814086 GO_REF:0000041 GO_REF:0000118 RGD:4145128 NCBI chrNW_004624789:11,435,955...11,448,867
Ensembl chrNW_004624789:11,435,779...11,448,984
JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IEA UniProt GO_REF:0000041 NCBI chrNW_004624784:14,467,515...14,474,954
Ensembl chrNW_004624784:14,467,533...14,474,954
JBrowse link
G Ireb2 iron responsive element binding protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3695992|PMID:15831703) MGI
Ensembl
PMID:15831703 GO_REF:0000107 MGI:3695992 NCBI chrNW_004624894:2,446,014...2,498,650
Ensembl chrNW_004624894:2,445,704...2,499,009
JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000104 NCBI chrNW_004624794:212,220...215,891
Ensembl chrNW_004624794:212,226...215,931
JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IEA UniProt GO_REF:0000041 NCBI chrNW_004624906:910,306...914,898
Ensembl chrNW_004624906:910,313...914,898
JBrowse link
G Uros uroporphyrinogen III synthase involved_in IEA UniProt GO_REF:0000041 NCBI chrNW_004624737:21,340,193...21,383,452 JBrowse link
quercetin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lct lactase involved_in ISO (PMID:12594539) UniProt PMID:12594539 NCBI chrNW_004624732:35,125,995...35,177,055
Ensembl chrNW_004624732:35,125,287...35,175,062
JBrowse link
regulation of heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srrd SRR1 domain containing involved_in ISO (MGI:6282940|PMID:28802827) UniProt PMID:28802827 MGI:6282940 NCBI chrNW_004624747:3,033,705...3,041,667
Ensembl chrNW_004624747:3,033,745...3,041,090
JBrowse link
G Tmem14a transmembrane protein 14A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624855:3,388,292...3,411,943
Ensembl chrNW_004624855:3,388,847...3,394,990
JBrowse link
G Tmem14c transmembrane protein 14C involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5581691|PMID:25157825) TreeGrafter
MGI
PMID:25157825 GO_REF:0000118 MGI:5581691 NCBI chrNW_004624756:15,179,801...15,187,475 JBrowse link
regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:6,296,975...6,318,266
Ensembl chrNW_004624786:6,298,243...6,317,743
JBrowse link
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (PMID:33208952)
(MGI:6492453|PMID:33208952)
(PMID:31117290)
UniProt PMID:31117290 PMID:33208952 MGI:6492453 NCBI chrNW_004624828:6,255,889...6,268,697
Ensembl chrNW_004624828:6,259,618...6,268,272
JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO (MGI:3588610|PMID:16037214) MGI PMID:16037214 MGI:3588610 NCBI chrNW_004624777:18,540,006...18,619,881
Ensembl chrNW_004624777:18,546,799...18,619,947
JBrowse link
rhodopsin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grk3 G protein-coupled receptor kinase 3 ISO RGD PMID:17573483 RGD:5685371 NCBI chrNW_004624747:1,567,540...1,758,251
Ensembl chrNW_004624747:1,576,681...1,758,201
JBrowse link
xanthophyll biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coq6 coenzyme Q6, monooxygenase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624734:27,610,144...27,625,670
Ensembl chrNW_004624734:27,610,248...27,626,298
JBrowse link
zeaxanthin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe65 retinoid isomerohydrolase RPE65 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624742:27,302,222...27,319,549
Ensembl chrNW_004624742:27,302,453...27,319,203
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15033
    metabolic process 9014
      pigment metabolic process 64
        anthocyanin-containing compound metabolic process + 0
        aurone metabolic process + 0
        flavone metabolic process + 2
        heme metabolic process + 31
        melanin metabolic process + 26
        phlobaphene metabolic process + 0
        pigment biosynthetic process + 52
        pigment catabolic process + 4
        pigment metabolic process involved in pigmentation + 3
paths to the root