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ONTOLOGY REPORT - ANNOTATIONS


Term:pigment metabolic process
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Accession:GO:0042440 term browser browse the term
Definition:The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.
Synonyms:exact_synonym: pigment metabolism



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flavone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha ISO hesperetin RGD PMID:22767158 RGD:7242166 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 involved_in ISO (PMID:18052087) BHF-UCL PMID:18052087 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 involved_in ISO (PMID:18052087) BHF-UCL PMID:18052087 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
heme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate, delta-, dehydratase involved_in IMP
IDA
(PMID:5393940)
(PMID:14050799)
MGI PMID:5393940 PMID:14050799 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
JBrowse link
G Alas1 aminolevulinic acid synthase 1 involved_in IMP (PMID:33307066) MGI PMID:33307066 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
JBrowse link
G Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 involved_in
acts_upstream_of_or_within
ISO
IDA
IBA
IGI
IMP
(PMID:16103131)
(PMID:12928484)
(PMID:16782876)
MGI
GO_Central
PMID:12928484 PMID:16103131 PMID:16782876 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:63,853,453...63,970,298
Ensembl chr11:63,853,453...63,970,294
JBrowse link
G Cox15 cytochrome c oxidase assembly protein 15 involved_in IBA
ISO
(PMID:12474143) GO_Central
MGI
PMID:12474143 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr19:43,721,693...43,741,439
Ensembl chr19:43,721,693...43,741,439
JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IDA (PMID:8407975) MGI PMID:8407975 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
JBrowse link
G Fech ferrochelatase involved_in IMP (PMID:15677551) MGI PMID:15677551 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322
JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IMP (PMID:8563760) MGI PMID:8563760 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525
JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IDA (PMID:3346226) MGI PMID:3346226 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760
JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IMP (PMID:17360334) MGI PMID:17360334 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610
JBrowse link
G Uros uroporphyrinogen III synthase involved_in IMP (PMID:16532394) MGI PMID:16532394 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801
JBrowse link
heme B biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP-binding cassette, sub-family B member 6 NOT|involved_in ISO (PMID:22655043) UniProt PMID:22655043 NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036
JBrowse link
G Alad aminolevulinate, delta-, dehydratase involved_in IDA
IMP
(PMID:14050799)
(PMID:5393940)
MGI PMID:5393940 PMID:14050799 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
JBrowse link
G Alas1 aminolevulinic acid synthase 1 involved_in IMP (PMID:33307066) MGI PMID:33307066 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IDA (PMID:8407975) MGI PMID:8407975 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
JBrowse link
G Fech ferrochelatase involved_in IMP (PMID:15677551) MGI PMID:15677551 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322
JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IMP (PMID:8563760) MGI PMID:8563760 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525
JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IDA (PMID:3346226) MGI PMID:3346226 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760
JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IMP (PMID:17360334) MGI PMID:17360334 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610
JBrowse link
G Uros uroporphyrinogen III synthase involved_in IMP (PMID:16532394) MGI PMID:16532394 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801
JBrowse link
heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb10 ATP-binding cassette, sub-family B member 10 involved_in IMP (MGI:5648801|PMID:24421385) UniProt PMID:24421385 MGI:5648801 NCBI chr 8:124,679,198...124,709,877
Ensembl chr 8:124,679,198...124,709,861
JBrowse link
G Alad aminolevulinate, delta-, dehydratase acts_upstream_of_or_within
involved_in
ISO
IDA
IBA
(PMID:14050799), (PMID:4959158), (PMID:4981581) RGD
MGI
GO_Central
PMID:1764448 PMID:4959158 PMID:4981581 PMID:14050799 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1599020 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
JBrowse link
G Alas1 aminolevulinic acid synthase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
JBrowse link
G Alas2 aminolevulinic acid synthase 2, erythroid involved_in IMP
IBA
(MGI:3694153|PMID:9446639) UniProt
GO_Central
PMID:9446639 GO_REF:0000033 MGI:3694153 NCBI chr  X:149,330,443...149,353,614
Ensembl chr  X:149,330,371...149,353,634
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in IMP
IBA
ISO
(MGI:5447588|PMID:23135403) UniProt
GO_Central
MGI
PMID:23135403 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:5447588 NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970
JBrowse link
G Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 involved_in
acts_upstream_of_or_within
IEA UniProt GO_REF:0000002 GO_REF:0000043 MGI:1354194 MGI:2152098 NCBI chr11:63,853,453...63,970,298
Ensembl chr11:63,853,453...63,970,294
JBrowse link
G Cpox coproporphyrinogen oxidase acts_upstream_of_or_within
involved_in
ISO
IDA
(PMID:8407975) RGD
MGI
PMID:3955059 PMID:8407975 GO_REF:0000096 MGI:4417868 RGD:1600961 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within
involved_in
ISO
TAS
IDA
IBA
IMP
(PMID:12149233)
(PMID:15496139), (PMID:16503645)
(PMID:16306232)
(PMID:9989256)
(PMID:8611576)
RGD
MGI
GO_Central
PMID:3955059 PMID:8611576 PMID:9989256 PMID:12149233 PMID:15496139 More... GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1600961 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322
JBrowse link
G Fxn frataxin acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr19:24,236,909...24,257,954
Ensembl chr19:24,238,817...24,257,969
JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in ISO
IBA
MGI
GO_Central
GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525
JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within IMP (PMID:10617683) MGI PMID:10617683 NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153
JBrowse link
G Iba57 IBA57 homolog, iron-sulfur cluster assembly acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr11:59,046,194...59,055,391
Ensembl chr11:59,046,195...59,054,565
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:35,861,846...35,869,732
Ensembl chr  X:35,861,859...35,869,732
JBrowse link
G Ppox protoporphyrinogen oxidase involved_in
acts_upstream_of_or_within
ISO
IBA
IDA
(PMID:3346226) RGD
GO_Central
MGI
PMID:3346226 PMID:3955059 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1600961 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760
JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 acts_upstream_of_or_within IMP (PMID:11739192) MGI PMID:11739192 NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953
JBrowse link
G Slc25a39 solute carrier family 25, member 39 acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr11:102,293,795...102,299,501
Ensembl chr11:102,293,811...102,298,772
JBrowse link
G Snx3 sorting nexin 3 acts_upstream_of_or_within ISO (PMID:23416069) MGI PMID:23416069 NCBI chr10:42,378,050...42,411,365
Ensembl chr10:42,378,026...42,411,377
JBrowse link
G Srrd SRR1 domain containing acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr 5:112,485,257...112,490,921
Ensembl chr 5:112,485,258...112,490,906
JBrowse link
G Tmem14c transmembrane protein 14C acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr13:41,169,726...41,176,058
Ensembl chr13:41,169,768...41,176,062
JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in
acts_upstream_of_or_within
IBA
IMP
(PMID:17360334) GO_Central
MGI
PMID:17360334 GO_REF:0000033 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610
JBrowse link
G Uros uroporphyrinogen III synthase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801
JBrowse link
heme catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blvra biliverdin reductase A involved_in
acts_upstream_of_or_within
ISO (PMID:12079357) MGI PMID:12079357 GO_REF:0000119 MGI:4834177 NCBI chr 2:126,912,549...126,939,004
Ensembl chr 2:126,912,585...126,939,004
JBrowse link
G Blvrb biliverdin reductase B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:27,147,403...27,165,406
Ensembl chr 7:27,147,403...27,165,569
JBrowse link
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within
involved_in
ISO
IGI
IBA
(PMID:31571584) RGD
MGI
GO_Central
PMID:15226268 PMID:31571584 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1547877 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hmox2 heme oxygenase 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606
JBrowse link
heme metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP-binding cassette, sub-family B member 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036
JBrowse link
G Cyb5r4 cytochrome b5 reductase 4 acts_upstream_of_or_within ISO (PMID:10611283) MGI PMID:10611283 NCBI chr 9:86,904,082...86,959,827
Ensembl chr 9:86,904,067...86,959,827
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 acts_upstream_of_or_within IDA (PMID:16183037) MGI PMID:16183037 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Hebp1 heme binding protein 1 acts_upstream_of_or_within IC (PMID:12413491), (PMID:9813049) MGI PMID:9813049 PMID:12413491 NCBI chr 6:135,114,517...135,145,213
Ensembl chr 6:135,114,520...135,175,020
JBrowse link
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within IDA (PMID:16183037) MGI PMID:16183037 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hpx hemopexin involved_in
acts_upstream_of_or_within
IBA
IMP
(PMID:18556779) GO_Central
MGI
PMID:18556779 GO_REF:0000033 NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344
JBrowse link
G Slc48a1 solute carrier family 48 (heme transporter), member 1 involved_in IMP (PMID:31571584) MGI PMID:31571584 NCBI chr15:97,682,246...97,690,573
Ensembl chr15:97,676,401...97,690,573
JBrowse link
G Slco1a6 solute carrier organic anion transporter family, member 1a6 acts_upstream_of_or_within IMP (PMID:20644253) MGI PMID:20644253 NCBI chr 6:142,031,487...142,131,903
Ensembl chr 6:142,031,487...142,154,247
JBrowse link
G Urod uroporphyrinogen decarboxylase acts_upstream_of_or_within IMP (PMID:11134514) MGI PMID:11134514 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610
JBrowse link
heme O biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate, delta-, dehydratase involved_in IDA
IMP
(PMID:14050799)
(PMID:5393940)
MGI PMID:5393940 PMID:14050799 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
JBrowse link
G Alas1 aminolevulinic acid synthase 1 involved_in IMP (PMID:33307066) MGI PMID:33307066 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
JBrowse link
G Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 involved_in IGI (PMID:12928484) MGI PMID:12928484 NCBI chr11:63,853,453...63,970,298
Ensembl chr11:63,853,453...63,970,294
JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IDA (PMID:8407975) MGI PMID:8407975 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
JBrowse link
G Fech ferrochelatase involved_in IMP (PMID:15677551) MGI PMID:15677551 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322
JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IMP (PMID:8563760) MGI PMID:8563760 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525
JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IDA (PMID:3346226) MGI PMID:3346226 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760
JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IMP (PMID:17360334) MGI PMID:17360334 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610
JBrowse link
G Uros uroporphyrinogen III synthase involved_in IMP (PMID:16532394) MGI PMID:16532394 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801
JBrowse link
heme oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 involved_in ISO
IBA
MGI
GO_Central
GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hmox2 heme oxygenase 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606
JBrowse link
melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G a nonagouti acts_upstream_of_or_within IMP (PMID:7665913) MGI PMID:7665913 NCBI chr 2:154,792,519...154,892,932
Ensembl chr 2:154,633,322...154,892,932
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in IDA (MGI:4412464|PMID:11434569) UniProt PMID:11434569 MGI:4412464 NCBI chr  X:101,290,984...101,295,787
Ensembl chr  X:101,290,987...101,295,787
JBrowse link
G Ctns cystinosis, nephropathic acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr11:73,073,959...73,089,869
Ensembl chr11:73,074,422...73,089,868
JBrowse link
G Dct dopachrome tautomerase acts_upstream_of_or_within IMP (PMID:7665913) MGI PMID:7665913 NCBI chr14:118,250,202...118,289,658
Ensembl chr14:118,250,202...118,289,656
JBrowse link
G Ddt D-dopachrome tautomerase acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr10:75,607,067...75,609,208
Ensembl chr10:75,607,064...75,609,248
JBrowse link
G Mc1r melanocortin 1 receptor acts_upstream_of_or_within IMP (PMID:7665913) MGI PMID:7665913 NCBI chr 8:124,133,839...124,137,483
Ensembl chr 8:124,133,846...124,137,483
JBrowse link
G Mfsd12 major facilitator superfamily domain containing 12 acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr10:81,193,325...81,202,059
Ensembl chr10:81,193,325...81,202,059
JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within IMP (PMID:7665913) MGI PMID:7665913 NCBI chr 9:74,975,183...75,130,970
Ensembl chr 9:74,978,297...75,130,970
JBrowse link
G Oca2 oculocutaneous albinism II involved_in
acts_upstream_of_or_within
IBA
IMP
(PMID:7665913), (PMID:9548375) GO_Central
MGI
PMID:7665913 PMID:9548375 GO_REF:0000033 NCBI chr 7:55,889,341...56,186,266
Ensembl chr 7:55,889,508...56,186,266
JBrowse link
G Pmel premelanosome protein acts_upstream_of_or_within IMP (PMID:7665913) MGI PMID:7665913 NCBI chr10:128,531,757...128,555,993
Ensembl chr10:128,540,064...128,556,107
JBrowse link
G Slc24a5 solute carrier family 24, member 5 acts_upstream_of IMP (PMID:18166528) MGI PMID:18166528 NCBI chr 2:124,910,076...124,930,316
Ensembl chr 2:124,910,044...124,930,597
JBrowse link
G Slc45a2 solute carrier family 45, member 2 acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr15:11,000,807...11,029,319
Ensembl chr15:11,000,807...11,029,319
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:95,587,125...95,632,438
Ensembl chr 9:95,587,135...95,632,428
JBrowse link
G Tyr tyrosinase involved_in
acts_upstream_of_or_within
ISO
IBA
IMP
(PMID:7665913)
(PMID:9548375)
MGI
GO_Central
PMID:7665913 PMID:9548375 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720
JBrowse link
G Tyrp1 tyrosinase-related protein 1 acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr 4:80,752,360...80,769,973
Ensembl chr 4:80,752,360...80,769,956
JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase involved_in IDA
IBA
IMP
(MGI:3690794|PMID:2169885)
(MGI:6827472|PMID:33100333)
UniProt
GO_Central
PMID:2169885 PMID:33100333 GO_REF:0000033 MGI:3690794 MGI:6827472 NCBI chr14:118,250,202...118,289,658
Ensembl chr14:118,250,202...118,289,656
JBrowse link
G Oca2 oculocutaneous albinism II involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:55,889,341...56,186,266
Ensembl chr 7:55,889,508...56,186,266
JBrowse link
G Slc45a2 solute carrier family 45, member 2 involved_in IMP
ISO
(MGI:7338895|PMID:35469906) UniProt
MGI
PMID:35469906 GO_REF:0000119 MGI:4834177 MGI:7338895 NCBI chr15:11,000,807...11,029,319
Ensembl chr15:11,000,807...11,029,319
JBrowse link
G Tyrp1 tyrosinase-related protein 1 involved_in TAS (MGI:3687692|PMID:9918801) UniProt PMID:9918801 MGI:3687692 NCBI chr 4:80,752,360...80,769,973
Ensembl chr 4:80,752,360...80,769,956
JBrowse link
melanin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 B cell leukemia/lymphoma 2 acts_upstream_of_or_within IMP (PMID:11709185) MGI PMID:11709185 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within IMP (PMID:9548375) MGI PMID:9548375 NCBI chr 9:74,975,183...75,130,970
Ensembl chr 9:74,978,297...75,130,970
JBrowse link
G Tyrp1 tyrosinase-related protein 1 acts_upstream_of_or_within IMP (PMID:9548375) MGI PMID:9548375 NCBI chr 4:80,752,360...80,769,973
Ensembl chr 4:80,752,360...80,769,956
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within IMP (PMID:22627278) MGI PMID:22627278 NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594
JBrowse link
negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in IMP (MGI:5912387|PMID:29025994) CACAO PMID:29025994 MGI:5912387 NCBI chr10:81,193,325...81,202,059
Ensembl chr10:81,193,325...81,202,059
JBrowse link
G Opn3 opsin 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:175,489,993...175,520,198
Ensembl chr 1:175,489,987...175,520,342
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2 involved_in IMP (MGI:5499726|PMID:16272156) UniProt PMID:16272156 MGI:5499726 NCBI chr 3:78,969,818...79,194,681
Ensembl chr 3:78,969,823...79,193,824
JBrowse link
G Slc24a5 solute carrier family 24, member 5 acts_upstream_of_or_within IMP (PMID:18166528) MGI PMID:18166528 NCBI chr 2:124,910,076...124,930,316
Ensembl chr 2:124,910,044...124,930,597
JBrowse link
G Wnt5a wingless-type MMTV integration site family, member 5A involved_in IDA (MGI:5619434|PMID:23569434) CACAO PMID:23569434 MGI:5619434 NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405
JBrowse link
pigment biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox2 SRY (sex determining region Y)-box 2 acts_upstream_of_or_within IMP (PMID:12036291) MGI PMID:12036291 NCBI chr 3:34,704,144...34,706,610
Ensembl chr 3:34,704,554...34,706,610
JBrowse link
pigment metabolic process involved in pigmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in IMP
IBA
ISO
(MGI:6492453|PMID:33208952) UniProt
GO_Central
MGI
PMID:33208952 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6492453 NCBI chr10:81,193,325...81,202,059
Ensembl chr10:81,193,325...81,202,059
JBrowse link
G Tbx2 T-box 2 acts_upstream_of_negative_effect IMP (MGI:6814712|PMID:26971330) UniProt PMID:26971330 MGI:6814712 NCBI chr11:85,723,441...85,732,774
Ensembl chr11:85,723,377...85,732,774
JBrowse link
positive regulation of heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP-binding cassette, sub-family B member 7 involved_in IMP
ISO
(MGI:6695684|PMID:30765471) UniProt
MGI
PMID:30765471 GO_REF:0000119 MGI:4834177 MGI:6695684 NCBI chr  X:103,324,171...103,457,452
Ensembl chr  X:103,324,263...103,457,462
JBrowse link
G Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 involved_in IMP (MGI:6450351|PMID:28495915) ARUK-UCL PMID:28495915 MGI:6450351 NCBI chr 4:117,692,240...117,726,502
Ensembl chr 4:117,691,703...117,732,395
JBrowse link
positive regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:26,640,943...26,692,567
Ensembl chr14:26,640,945...26,693,189
JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532
JBrowse link
G Cdh3 cadherin 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:107,237,484...107,283,543
Ensembl chr 8:107,237,523...107,283,929
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:84,376,037...84,391,418
Ensembl chr 8:84,379,306...84,391,323
JBrowse link
G Opn3 opsin 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:175,489,993...175,520,198
Ensembl chr 1:175,489,987...175,520,342
JBrowse link
G Pmel premelanosome protein involved_in IMP (MGI:5294257|PMID:21949658) CACAO PMID:21949658 MGI:5294257 NCBI chr10:128,531,757...128,555,993
Ensembl chr10:128,540,064...128,556,107
JBrowse link
G Rab38 RAB38, member RAS oncogene family involved_in ISO RGD
MGI
PMID:17043139 GO_REF:0000096 MGI:4417868 RGD:152025192 NCBI chr 7:88,079,481...88,140,780
Ensembl chr 7:88,079,481...88,140,780
JBrowse link
G Tyrp1 tyrosinase-related protein 1 involved_in IGI
ISO
(MGI:5294257|PMID:21949658) CACAO
MGI
PMID:21949658 GO_REF:0000119 MGI:4834177 MGI:5294257 NCBI chr 4:80,752,360...80,769,973
Ensembl chr 4:80,752,360...80,769,956
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 involved_in IC (MGI:5574413|PMID:24769727) BHF-UCL PMID:24769727 MGI:5574413 NCBI chr 2:44,873,523...45,007,378
Ensembl chr 2:44,873,644...45,007,407
JBrowse link
protoporphyrinogen IX biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpox coproporphyrinogen oxidase involved_in ISO
IBA
RGD
GO_Central
MGI
PMID:3814086 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:4145128 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
JBrowse link
G Ireb2 iron responsive element binding protein 2 acts_upstream_of_or_within IMP (PMID:15831703) MGI PMID:15831703 NCBI chr 9:54,769,942...54,819,812
Ensembl chr 9:54,771,073...54,819,814
JBrowse link
quercetin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lct lactase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:128,212,493...128,256,055
Ensembl chr 1:128,212,493...128,256,055
JBrowse link
regulation of heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srrd SRR1 domain containing involved_in IMP (MGI:6282940|PMID:28802827) UniProt PMID:28802827 MGI:6282940 NCBI chr 5:112,485,257...112,490,921
Ensembl chr 5:112,485,258...112,490,906
JBrowse link
G Tmem14a transmembrane protein 14A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:21,236,609...21,300,391
Ensembl chr 1:21,288,799...21,300,391
JBrowse link
G Tmem14c transmembrane protein 14C involved_in
acts_upstream_of_or_within
IBA
IMP
(PMID:25157825) GO_Central
MGI
PMID:25157825 GO_REF:0000033 NCBI chr13:41,169,726...41,176,058
Ensembl chr13:41,169,768...41,176,062
JBrowse link
regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosis, nephropathic involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:73,073,959...73,089,869
Ensembl chr11:73,074,422...73,089,868
JBrowse link
G Mfsd12 major facilitator superfamily domain containing 12 involved_in IMP
IBA
ISO
(MGI:6492453|PMID:33208952) UniProt
GO_Central
MGI
PMID:33208952 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6492453 NCBI chr10:81,193,325...81,202,059
Ensembl chr10:81,193,325...81,202,059
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 acts_upstream_of_or_within IMP (PMID:16037214) MGI PMID:16037214 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
rhodopsin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grk3 G protein-coupled receptor kinase 3 involved_in ISO RGD
MGI
PMID:17573483 GO_REF:0000096 MGI:4417868 RGD:5685371 NCBI chr 5:113,058,344...113,163,518
Ensembl chr 5:113,058,348...113,163,657
JBrowse link
zeaxanthin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe65 retinal pigment epithelium 65 involved_in ISO
IBA
MGI
GO_Central
GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 3:159,304,712...159,330,944
Ensembl chr 3:159,304,812...159,330,958
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    metabolic process 11001
      pigment metabolic process 73
        anthocyanin-containing compound metabolic process + 0
        aurone metabolic process + 0
        flavone metabolic process + 5
        heme metabolic process + 37
        melanin metabolic process + 27
        phlobaphene metabolic process + 0
        pigment biosynthetic process + 54
        pigment catabolic process + 4
        pigment metabolic process involved in pigmentation + 3
paths to the root