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ONTOLOGY REPORT - ANNOTATIONS


Term:indole-containing compound catabolic process
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Accession:GO:0042436 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton.
Synonyms:exact_synonym: indole derivative catabolic process;   indole derivative catabolism;   indole-containing compound breakdown;   indole-containing compound catabolism;   indole-containing compound degradation


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tryptophan catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase TAS Reactome Reactome:R-HSA-71240 NCBI chr 4:170,060,222...170,091,699
Ensembl chr 4:170,060,222...170,091,699
JBrowse link
G ACMSD aminocarboxymuconate semialdehyde decarboxylase TAS (PMID:12140278), (PMID:19843166) ParkinsonsUK-UCL PMID:12140278, PMID:19843166 NCBI chr 2:134,838,319...134,902,906
Ensembl chr 2:134,838,616...134,902,034
JBrowse link
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase TAS Reactome Reactome:R-HSA-71240 NCBI chr 2:42,767,087...42,801,002
Ensembl chr 2:42,767,089...42,792,593
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 TAS Reactome Reactome:R-HSA-71240 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 TAS Reactome Reactome:R-HSA-71240 NCBI chr 8:39,934,955...40,016,391
Ensembl chr 8:39,934,614...40,016,391
JBrowse link
G KMO kynurenine 3-monooxygenase TAS Reactome Reactome:R-HSA-71240 NCBI chr 1:241,531,883...241,595,642
Ensembl chr 1:241,532,134...241,595,642
JBrowse link
G KYAT1 kynurenine aminotransferase 1 TAS Reactome Reactome:R-HSA-71240 NCBI chr 9:128,832,942...128,882,523
Ensembl chr 9:128,819,663...128,881,931
Ensembl chr 9:128,819,663...128,881,931
JBrowse link
G KYNU kynureninase IEA
IMP
TAS
(PMID:17334708) InterPro
UniProtKB
Reactome
PMID:17334708 GO_REF:0000002, Reactome:R-HSA-71240 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase TAS Reactome Reactome:R-HSA-71240 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KYNU kynureninase IEA Ensembl GO_REF:0000107 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFMID arylformamidase IEA
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr17:78,185,102...78,207,702
Ensembl chr17:78,187,317...78,207,701
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 IEA
IBA
(PMID:21873635) InterPro
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000002, GO_REF:0000041 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 IEA
IBA
ISS
IDA
(PMID:21873635)
(PMID:17499941)
(PMID:17671174)
InterPro
GO_Central
UniProtKB
PMID:17499941, PMID:17671174, PMID:21873635 GO_REF:0000002, GO_REF:0000041 NCBI chr 8:39,934,955...40,016,391
Ensembl chr 8:39,934,614...40,016,391
JBrowse link
G KYNU kynureninase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase IEA
IDA
(PMID:27762317) InterPro
UniProtKB
PMID:27762317 GO_REF:0000002, GO_REF:0000041 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 18672
    metabolic process 12302
      cellular metabolic process 11278
        cellular aromatic compound metabolic process 6222
          aromatic compound catabolic process 646
            indole-containing compound catabolic process 10
              brevianamide F catabolic process 0
              fumiquinazoline F catabolic process 0
              indolalkylamine catabolic process + 10
              indole catabolic process 0
              indole glucosinolate catabolic process 0
              indole phytoalexin catabolic process 0
              indoleacetic acid catabolic process 0
              melatonin catabolic process 0
              serotonin catabolic process 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.