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ONTOLOGY REPORT - ANNOTATIONS


Term:serotonin biosynthetic process
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Accession:GO:0042427 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
Synonyms:exact_synonym: serotonin anabolism;   serotonin biosynthesis;   serotonin formation;   serotonin synthesis
 xref: Wikipedia:Serotonin



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serotonin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddc dopa decarboxylase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:10027744 PMID:21873635 RGD:5129182, RGD:13792537 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Tph1 tryptophan hydroxylase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:2683993|PMID:14697203)
UniProt
RGD
PMID:14697203 GO_REF:0000024 MGI:2683993 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
JBrowse link
G Tph2 tryptophan hydroxylase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424
JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:23098818 RGD:11353778 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Tph1 tryptophan hydroxylase 1 TAS RGD PMID:12153488 RGD:625621 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      nitrogen compound metabolic process 9922
        ammonium ion metabolic process 26
          serotonin metabolic process 14
            serotonin biosynthetic process 4
              negative regulation of serotonin biosynthetic process 0
              positive regulation of serotonin biosynthetic process 0
              regulation of serotonin biosynthetic process + 0
              serotonin biosynthetic process from tryptophan + 2
Path 2
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      cellular metabolic process 10656
        cellular aromatic compound metabolic process 5581
          phenol-containing compound metabolic process 128
            serotonin metabolic process 14
              serotonin biosynthetic process 4
                negative regulation of serotonin biosynthetic process 0
                positive regulation of serotonin biosynthetic process 0
                regulation of serotonin biosynthetic process + 0
                serotonin biosynthetic process from tryptophan + 2
paths to the root