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ONTOLOGY REPORT - ANNOTATIONS


Term:serotonin biosynthetic process
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Accession:GO:0042427 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
Synonyms:exact_synonym: serotonin anabolism;   serotonin biosynthesis;   serotonin formation;   serotonin synthesis
 xref: Wikipedia:Serotonin



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serotonin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDC dopa decarboxylase involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:10027744 PMID:21873635 RGD:5129182 NCBI chr 7:50,458,436...50,565,460
Ensembl chr 7:50,458,436...50,565,405
JBrowse link
G TPH1 tryptophan hydroxylase 1 involved_in IEA
ISS
UniProt GO_REF:0000024 GO_REF:0000041 NCBI chr11:18,017,555...18,046,269
Ensembl chr11:18,017,555...18,046,269
JBrowse link
G TPH2 tryptophan hydroxylase 2 involved_in IEA UniProt GO_REF:0000041 NCBI chr12:71,938,845...72,032,440
Ensembl chr12:71,938,845...72,186,618
JBrowse link
regulation of serotonin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH2 aldehyde dehydrogenase 2 family member involved_in ISS UniProt GO_REF:0000024 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 ISO RGD PMID:23098818 RGD:11353778 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18607
    metabolic process 11952
      nitrogen compound metabolic process 10087
        ammonium ion metabolic process 29
          serotonin metabolic process 15
            serotonin biosynthetic process 5
              negative regulation of serotonin biosynthetic process 0
              positive regulation of serotonin biosynthetic process 0
              regulation of serotonin biosynthetic process + 1
              serotonin biosynthetic process from tryptophan + 1
Path 2
Term Annotations click to browse term
  biological_process 18607
    metabolic process 11952
      cellular metabolic process 10866
        cellular aromatic compound metabolic process 6064
          phenol-containing compound metabolic process 135
            serotonin metabolic process 15
              serotonin biosynthetic process 5
                negative regulation of serotonin biosynthetic process 0
                positive regulation of serotonin biosynthetic process 0
                regulation of serotonin biosynthetic process + 1
                serotonin biosynthetic process from tryptophan + 1
paths to the root