Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:serotonin biosynthetic process
go back to main search page
Accession:GO:0042427 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
Synonyms:exact_synonym: serotonin anabolism;   serotonin biosynthesis;   serotonin formation;   serotonin synthesis
 xref: Wikipedia:Serotonin


show annotations for term's descendants           Sort by:
serotonin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddc dopa decarboxylase involved_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:10027744 GO_REF:0000033, RGD:5129182 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806 		JBrowse link
G Th tyrosine hydroxylase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Tph1 tryptophan hydroxylase 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000041
GO_REF:0000002
GO_REF:0000043
(PMID:14697203) 		UniProt
InterPro
RGD		 PMID:14697203 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 NCBI chr 1:106,293,695...106,314,628
Ensembl chr 1:106,085,953...106,312,484 		JBrowse link
G Tph2 tryptophan hydroxylase 2 involved_in IEA GO_REF:0000041
GO_REF:0000002
GO_REF:0000043 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000043 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:52,571,911...52,675,639 		JBrowse link
regulation of serotonin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:26711020) 		UniProt
Ensembl
RGD		 PMID:26711020 GO_REF:0000024 GO_REF:0000107 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:23098818 RGD:11353778 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Tph1 tryptophan hydroxylase 1 involved_in TAS
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:12153488 GO_REF:0000033, RGD:625621 NCBI chr 1:106,293,695...106,314,628
Ensembl chr 1:106,085,953...106,312,484 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      metabolic process 11533
        phenol-containing compound metabolic process 130
          serotonin metabolic process 17
            serotonin biosynthetic process 6
              negative regulation of serotonin biosynthetic process 0
              positive regulation of serotonin biosynthetic process 0
              regulation of serotonin biosynthetic process + 1
              serotonin biosynthetic process from tryptophan 2
paths to the root