ONTOLOGY REPORT - ANNOTATIONS
Term: serotonin biosynthetic process
Accession: GO:0042427
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Definition: The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
Synonyms: exact_synonym: serotonin anabolism; serotonin biosynthesis; serotonin formation; serotonin synthesis
xref: Wikipedia:Serotonin
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Ddc
dopa decarboxylase
involved_in
IDA IBA
GO_REF:0000033
GO_Central RGD
PMID:10027744
GO_REF:0000033, RGD:5129182
NCBI chr14:90,592,304...90,682,830
Ensembl chr14:86,378,685...86,469,208
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Tph1
tryptophan hydroxylase 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:14697203)
UniProt RGD
PMID:14697203
GO_REF:0000024
NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
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Tph2
tryptophan hydroxylase 2
involved_in
IEA
GO_REF:0000041
UniProt
GO_REF:0000041
NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424
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Aldh2
aldehyde dehydrogenase 2 family member
involved_in
ISS ISO
GO_REF:0000024 (PMID:26711020)
UniProt RGD
PMID:26711020
GO_REF:0000024
NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521
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Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
IDA
RGD
PMID:23098818
RGD:11353778
NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759
G
Tph1
tryptophan hydroxylase 1
TAS
RGD
PMID:12153488
RGD:625621
NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
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