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ONTOLOGY REPORT - ANNOTATIONS

Term:norepinephrine biosynthetic process
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Accession:GO:0042421 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
Synonyms:exact_synonym: levarterenol biosynthesis;   levarterenol biosynthetic process;   noradrenaline biosynthesis;   noradrenaline biosynthetic process;   norepinephrine anabolism;   norepinephrine biosynthesis;   norepinephrine formation;   norepinephrine synthesis


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norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856097|MGI:1856098 (PMID:4405722), (PMID:4858102) RGD PMID:4405722 PMID:4858102 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within 		TAS
IMP
IEA
ISS
ISO
IBA 		GO_REF:0000041
GO_REF:0000024
(PMID:27148966)
GO_REF:0000033
MGI:1857556 (PMID:10051631), (PMID:9603211)
(PMID:27148966), (PMID:7715704)
GO_REF:0000107 		UniProt
RGD
GO_Central
Ensembl		 PMID:7715704 PMID:9603211 PMID:10051631 PMID:27148966 PMID:11914591 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107, RGD:727567, RGD:1625403 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO
IEA 		MGI:2153826 (PMID:10835639)
GO_REF:0000107 		RGD
Ensembl		 PMID:10835639 GO_REF:0000107 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 acts_upstream_of_positive_effect ISO
IEA 		(PMID:19008477)
GO_REF:0000107 		RGD
Ensembl		 PMID:19008477 GO_REF:0000107 NCBI chr16:37,928,145...37,931,488
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Insm1 INSM transcriptional repressor 1 involved_in ISO (PMID:18094025) RGD PMID:18094025 NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Kl Klotho IMP RGD PMID:20086041 RGD:10403068 NCBI chr12:5,326,003...5,367,016
Ensembl chr12:490,399...530,080 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        amine metabolic process 127
          biogenic amine metabolic process 115
            catecholamine metabolic process 68
              norepinephrine metabolic process 21
                norepinephrine biosynthetic process 10
paths to the root