Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:dopamine metabolic process
go back to main search page
Accession:GO:0042417 term browser browse the term
Definition:The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
Synonyms:exact_synonym: dopamine metabolism


show annotations for term's descendants           Sort by:
 
dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:MGI:1856098|MGI:MGI:1856466 (MGI:MGI:50550|PMID:1752214), (MGI:MGI:65000|PMID:8174230) RGD PMID:1752214, PMID:8174230 MGI:MGI:50550, MGI:MGI:65000, MGI:MGI:71923 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Comt catechol-O-methyltransferase ISO
IBA
MGI:MGI:2178542|MGI:MGI:4830700 (MGI:MGI:4830461|PMID:19930170), (MGI:MGI:5510279|PMID:23863468)
PMID:21873635
RGD PMID:19930170, PMID:23863468, PMID:21873635 MGI:MGI:4830461, MGI:MGI:5510279, RGD:13792537 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:10945868 RGD:1599723 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Ddc dopa decarboxylase TAS RGD PMID:7567987 RGD:727686 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Drd2 dopamine receptor D2 ISO (MGI:MGI:68905|PMID:7925842) RGD PMID:7925842 MGI:MGI:68905 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO
IEA
MGI:MGI:1928285 (MGI:MGI:2384280|PMID:11160454)
GO_REF:0000107
RGD
Ensembl
PMID:11160454 GO_REF:0000107, MGI:MGI:2384280 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO MGI:MGI:1857299 (MGI:MGI:1321418|PMID:9886073), (MGI:MGI:65825|PMID:7509865), (MGI:MGI:65928|PMID:1432691) RGD PMID:1432691, PMID:7509865, PMID:9886073 MGI:MGI:1321418, MGI:MGI:65825, MGI:MGI:65928 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:166,985,468...166,989,681
Ensembl chr 1:166,986,013...166,988,062
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 ISO MGI:MGI:3527173 (MGI:MGI:6150107|PMID:28327638) RGD PMID:28327638 MGI:MGI:6150107 NCBI chr 2:46,372,488...46,476,162
Ensembl chr 2:46,372,518...46,476,203
JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP RGD PMID:15544851 RGD:1580153 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 ISO MGI:MGI:2429971 (MGI:MGI:3529728|PMID:12385813) RGD PMID:12385813 MGI:MGI:3529728 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase NOT ISO MGI:MGI:2678247 (MGI:MGI:2675710|PMID:12915482)
MGI:MGI:3055212 (MGI:MGI:3525458|PMID:15684050)
RGD PMID:12915482, PMID:15684050 MGI:MGI:2675710, MGI:MGI:3525458 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Snca synuclein alpha ISO MGI:MGI:1889011 (MGI:MGI:3057254|PMID:15465911) RGD PMID:15465911 MGI:MGI:3057254 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sncaip synuclein, alpha interacting protein ISO
ISS
(PMID:14506261)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:14506261 GO_REF:0000024 NCBI chr18:47,739,284...47,877,679
Ensembl chr18:47,739,140...47,877,676
JBrowse link
G Sncb synuclein, beta ISO
IEA
MGI:MGI:1277151 (MGI:MGI:3057254|PMID:15465911)
GO_REF:0000107
RGD
Ensembl
PMID:15465911 GO_REF:0000107, MGI:MGI:3057254 NCBI chr17:10,384,472...10,392,776
Ensembl chr17:10,384,511...10,392,843
JBrowse link
G Spr sepiapterin reductase ISO MGI:MGI:3757641 (MGI:MGI:3722569|PMID:16532389) RGD PMID:16532389 MGI:MGI:3722569 NCBI chr 4:116,912,343...116,916,073
Ensembl chr 4:116,912,351...116,916,236
JBrowse link
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:20097214 RGD:6903884 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:20097214 RGD:6903884 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IEP RGD PMID:12438507 RGD:704388 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:19818757 RGD:5143981 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Dao D-amino-acid oxidase IEA
ISO
GO_REF:0000107
(PMID:17303072)
Ensembl
RGD
PMID:17303072 GO_REF:0000107 NCBI chr12:48,353,691...48,373,647
Ensembl chr12:48,354,196...48,365,784
JBrowse link
G Ddc dopa decarboxylase IDA
IEA
GO_REF:0000041 UniProt PMID:12703659 GO_REF:0000041, RGD:4139893 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO (PMID:16338639) RGD PMID:16338639 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO MGI:MGI:3027995 (MGI:MGI:3046856|PMID:15218106) RGD PMID:15218106 MGI:MGI:3046856 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IEA
ISO
GO_REF:0000107
MGI:MGI:2429971 (MGI:MGI:1203924|PMID:9608532), (MGI:MGI:3767764|PMID:16782508)
Ensembl
RGD
PMID:9608532, PMID:16782508 GO_REF:0000107, MGI:MGI:1203924, MGI:MGI:3767764 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO MGI:MGI:2386303 (MGI:MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:MGI:2386819 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Snca synuclein alpha ISO MGI:MGI:1888382 (MGI:MGI:1352916|PMID:10707987) RGD PMID:10707987 MGI:MGI:1352916 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO
ISS
(MGI:MGI:3622848|PMID:16257223)
GO_REF:0000024
RGD
UniProt
PMID:16257223 GO_REF:0000024, MGI:MGI:3622848 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Th tyrosine hydroxylase ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase IDA
IBA
ISO
IMP
PMID:21873635
MGI:MGI:1860450 (MGI:MGI:2386819|PMID:9520487), (MGI:MGI:72094|PMID:7715703), (MGI:MGI:77787|PMID:7592982)
PMID:11943812
RGD PMID:7592982, PMID:7715703, PMID:9520487, PMID:2427363, PMID:21873635, PMID:11943812, PMID:19584816 MGI:MGI:2386819, MGI:MGI:72094, MGI:MGI:77787, RGD:1580046, RGD:13792537, RGD:5129111, RGD:5130972 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
dopamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase ISO (MGI:MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:MGI:2386819 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Dbh dopamine beta-hydroxylase IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
MGI:MGI:1857556 (MGI:MGI:1332340|PMID:10051631), (MGI:MGI:5787847|PMID:27148966), (MGI:MGI:72180|PMID:7715704)
(PMID:3443096), (PMID:7961964)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:3443096, PMID:7715704, PMID:7961964, PMID:10051631, PMID:27148966, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1332340, MGI:MGI:5787847, MGI:MGI:72180, RGD:13792537 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Maoa monoamine oxidase A ISO
IEA
(MGI:MGI:2386819|PMID:9520487)
GO_REF:0000107
RGD
Ensembl
PMID:9520487 GO_REF:0000107, MGI:MGI:2386819 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,124,498...22,206,565
Ensembl chr 1:22,124,495...22,206,505
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO MGI:MGI:2386303 (MGI:MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:MGI:2386819 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
negative regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IMP RGD PMID:15190105 RGD:2289786 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:17018023 RGD:1625003 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Itgam integrin subunit alpha M ISO (MGI:MGI:3814938|PMID:18981141) RGD PMID:18981141 MGI:MGI:3814938 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Snca synuclein alpha IMP PMID:11943812 BHF-UCL PMID:11943812 RGD:5129111 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Park7 Parkinsonism associated deglycase ISO
IEA
ISS
(PMID:19703902)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
ParkinsonsUK-UCL
PMID:19703902 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Vps35 VPS35 retromer complex component ISO (MGI:MGI:5694519|PMID:26203154) RGD PMID:26203154 MGI:MGI:5694519 NCBI chr19:27,464,937...27,500,636
Ensembl chr19:27,464,937...27,500,636
JBrowse link
positive regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:11239920 RGD:10047061 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO MGI:MGI:3027995 (MGI:MGI:3046856|PMID:15218106) RGD PMID:15218106 MGI:MGI:3046856 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO (PMID:8643611) RGD PMID:8643611 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Maob monoamine oxidase B IMP RGD PMID:12175458 RGD:2316765 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Npy neuropeptide Y IDA RGD PMID:19579268 RGD:10448966 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO MGI:MGI:1926253 (MGI:MGI:3618656|PMID:11282258) RGD PMID:11282258 MGI:MGI:3618656 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Drd1 dopamine receptor D1 ISO
IEA
MGI:MGI:1857158 (MGI:MGI:2136539|PMID:11438590)
GO_REF:0000107
RGD
Ensembl
PMID:11438590 GO_REF:0000107, MGI:MGI:2136539 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd4 dopamine receptor D4 ISO
IEA
MGI:MGI:2178631 (MGI:MGI:1097029|PMID:9323127)
GO_REF:0000107
RGD
Ensembl
PMID:9323127 GO_REF:0000107, MGI:MGI:1097029 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO
ISS
(MGI:MGI:1927024|PMID:11080193)
GO_REF:0000024
RGD
UniProt
PMID:11080193 GO_REF:0000024, MGI:MGI:1927024 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 ISO
IEA
(MGI:MGI:2671567|PMID:12915123)
GO_REF:0000107
RGD
Ensembl
PMID:12915123 GO_REF:0000107, MGI:MGI:2671567 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Pde1b phosphodiesterase 1B ISO MGI:MGI:3604470 (MGI:MGI:3769297|PMID:17559891) RGD PMID:17559891 MGI:MGI:3769297 NCBI chr 7:145,117,951...145,147,711
Ensembl chr 7:145,117,951...145,145,376
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing ISO MGI:MGI:5006973 (MGI:MGI:5466578|PMID:22214848) RGD PMID:22214848 MGI:MGI:5466578 NCBI chr 9:81,566,074...81,634,531
Ensembl chr 9:81,566,074...81,634,534
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO (PMID:22314364) RGD PMID:22314364 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO MGI:MGI:2386303 (MGI:MGI:2386819|PMID:9520487), (MGI:MGI:894559|PMID:9247269) RGD PMID:9247269, PMID:9520487 MGI:MGI:2386819, MGI:MGI:894559 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:8574643 RGD:2305963 NCBI chr 2:240,021,152...240,118,971
Ensembl chr 2:240,021,152...240,118,971
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      nitrogen compound metabolic process 10366
        organonitrogen compound metabolic process 7153
          catecholamine metabolic process 59
            dopamine metabolic process 44
              dopamine biosynthetic process + 16
              dopamine catabolic process 6
              negative regulation of dopamine metabolic process + 4
              positive regulation of dopamine metabolic process + 8
              regulation of dopamine metabolic process + 22
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      cellular metabolic process 11085
        cellular aromatic compound metabolic process 5715
          phenol-containing compound metabolic process 124
            catechol-containing compound metabolic process 59
              catecholamine metabolic process 59
                dopamine metabolic process 44
                  dopamine biosynthetic process + 16
                  dopamine catabolic process 6
                  negative regulation of dopamine metabolic process + 4
                  positive regulation of dopamine metabolic process + 8
                  regulation of dopamine metabolic process + 22
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.