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ONTOLOGY REPORT - ANNOTATIONS


Term:norepinephrine metabolic process
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Accession:GO:0042415 term browser browse the term
Definition:The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
Synonyms:exact_synonym: levarterenol metabolic process;   levarterenol metabolism;   noradrenaline metabolic process;   noradrenaline metabolism;   norepinephrine metabolism


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norepinephrine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1B1 aldo-keto reductase family 1 member B ISO RGD PMID:10424772 RGD:8548769 NCBI chr18:14,593,516...14,752,316
Ensembl chr18:14,593,548...14,752,310
JBrowse link
G ATP7A ATPase copper transporting alpha ISO (MGI:MGI:53851|PMID:4147174) MGI PMID:4147174 MGI:MGI:53851, MGI:MGI:71923 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,874...62,110,058
JBrowse link
G EPAS1 endothelial PAS domain protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:94,167,759...94,253,662
Ensembl chr 3:94,165,815...94,254,079
JBrowse link
G LY6E lymphocyte antigen 6 family member E ISO (MGI:MGI:2157257|PMID:11784869) MGI PMID:11784869 MGI:MGI:2157257 NCBI chr 4:1,336,112...1,341,112 JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:3945626 RGD:5130757 NCBI chr12:22,648,396...22,651,520
Ensembl chr12:22,648,397...22,650,002
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase IEA Ensembl GO_REF:0000107 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,511...6,730,881
JBrowse link
G RNF180 ring finger protein 180 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:42,686,225...42,951,928
Ensembl chr16:42,686,978...42,953,592
JBrowse link
G RTL4 retrotransposon Gag like 4 IEA Ensembl GO_REF:0000107 NCBI chr  X:91,920,451...92,333,326
Ensembl chr  X:92,223,747...92,335,430
JBrowse link
G SPR sepiapterin reductase ISO (MGI:MGI:3722569|PMID:16532389) MGI PMID:16532389 MGI:MGI:3722569 NCBI chr 3:69,889,448...69,894,747
Ensembl chr 3:69,887,386...69,894,758
JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO (MGI:MGI:53801|PMID:4405722)
(MGI:MGI:53940|PMID:4858102)
MGI PMID:4405722, PMID:4858102 MGI:MGI:53801, MGI:MGI:53940 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,874...62,110,058
JBrowse link
G DBH dopamine beta-hydroxylase IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr 1:273,204,407...273,225,562
Ensembl chr 1:273,204,400...273,225,558
JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chr 3:94,167,759...94,253,662
Ensembl chr 3:94,165,815...94,254,079
JBrowse link
G GATA3 GATA binding protein 3 IEA Ensembl GO_REF:0000107 NCBI chr10:63,367,684...63,397,977
Ensembl chr10:63,367,660...63,388,859
JBrowse link
G INSM1 INSM transcriptional repressor 1 ISO (MGI:MGI:3772428|PMID:18094025) UniProtKB PMID:18094025 MGI:MGI:3772428 NCBI chr17:28,379,529...28,382,554 JBrowse link
G KL klotho ISO RGD PMID:20086041 RGD:10403068 NCBI chr11:9,427,236...9,479,251
Ensembl chr11:9,427,198...9,478,346
JBrowse link
G LOC100511166 DBH-like monooxygenase protein 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:7,742,254...7,751,098 JBrowse link
G MOXD1 monooxygenase DBH like 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:31,282,491...31,367,589
Ensembl chr 1:31,282,506...31,369,408
JBrowse link
G TH tyrosine hydroxylase IEA Ensembl GO_REF:0000107 NCBI chr 2:1,499,628...1,506,180
Ensembl chr 2:1,499,618...1,506,615
JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAND2 heart and neural crest derivatives expressed 2 IEA Ensembl GO_REF:0000107 NCBI chr14:16,460,089...16,462,979
Ensembl chr14:16,460,119...16,462,735
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16545
    metabolic process 10584
      nitrogen compound metabolic process 8919
        organonitrogen compound metabolic process 6091
          catecholamine metabolic process 56
            norepinephrine metabolic process 17
              norepinephrine biosynthetic process + 10
              norepinephrine catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 16545
    metabolic process 10584
      cellular metabolic process 9578
        cellular aromatic compound metabolic process 5111
          phenol-containing compound metabolic process 116
            catechol-containing compound metabolic process 56
              catecholamine metabolic process 56
                norepinephrine metabolic process 17
                  norepinephrine biosynthetic process + 10
                  norepinephrine catabolic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.