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ONTOLOGY REPORT - ANNOTATIONS


Term:norepinephrine metabolic process
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Accession:GO:0042415 term browser browse the term
Definition:The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
Synonyms:exact_synonym: levarterenol metabolic process;   levarterenol metabolism;   noradrenaline metabolic process;   noradrenaline metabolism;   norepinephrine metabolism


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norepinephrine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b3 aldo-keto reductase family 1, member B3 (aldose reductase) ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 6:34,303,930...34,317,489
Ensembl chr 6:34,302,434...34,317,478
JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide IMP (MGI:MGI:53851|PMID:4147174) MGI PMID:4147174 MGI:MGI:53851, MGI:MGI:71923 NCBI chr  X:106,027,224...106,128,161
Ensembl chr  X:106,027,276...106,124,926
JBrowse link
G Epas1 endothelial PAS domain protein 1 IMP (MGI:MGI:1313089|PMID:9808618) MGI PMID:9808618 MGI:MGI:1313089 NCBI chr17:86,753,864...86,833,410
Ensembl chr17:86,753,700...86,833,410
JBrowse link
G Ly6e lymphocyte antigen 6 complex, locus E IMP (MGI:MGI:2157257|PMID:11784869) MGI PMID:11784869 MGI:MGI:2157257 NCBI chr15:74,955,025...74,959,904
Ensembl chr15:74,955,051...74,959,905
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr11:98,386,623...98,388,180
Ensembl chr11:98,386,450...98,388,181
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP (MGI:MGI:3047192|PMID:15249681) MGI PMID:15249681 MGI:MGI:3047192 NCBI chr17:10,840,359...12,063,370
Ensembl chr17:10,840,384...12,063,361
JBrowse link
G Rnf180 ring finger protein 180 IMP
IBA
(MGI:MGI:5505713|PMID:23926250)
(MGI:MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:21873635, PMID:23926250 MGI:MGI:5505713, MGI:MGI:6201960 NCBI chr13:105,130,567...105,294,818
Ensembl chr13:105,130,001...105,294,815
JBrowse link
G Rtl4 retrotransposon Gag like 4 IMP (MGI:MGI:5749620|PMID:26402067) MGI PMID:26402067 MGI:MGI:5749620 NCBI chr  X:144,688,209...145,122,414
Ensembl chr  X:144,688,907...145,122,411
JBrowse link
G Spr sepiapterin reductase IMP (MGI:MGI:3722569|PMID:16532389) MGI PMID:16532389 MGI:MGI:3722569 NCBI chr 6:85,133,680...85,137,764
Ensembl chr 6:85,130,176...85,137,766
JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase, Cu++ transporting, alpha polypeptide IMP (MGI:MGI:53801|PMID:4405722)
(MGI:MGI:53940|PMID:4858102)
MGI PMID:4405722, PMID:4858102 MGI:MGI:53801, MGI:MGI:53940 NCBI chr  X:106,027,224...106,128,161
Ensembl chr  X:106,027,276...106,124,926
JBrowse link
G Dbh dopamine beta hydroxylase ISO
IBA
IMP
(MGI:MGI:6201960|PMID:21873635)
(MGI:MGI:5787847|PMID:27148966), (MGI:MGI:72180|PMID:7715704)
(MGI:MGI:1203930|PMID:9603211), (MGI:MGI:1332340|PMID:10051631)
RGD
GO_Central
UniProtKB
MGI
PMID:7715704, PMID:9603211, PMID:10051631, PMID:21873635, PMID:27148966 GO_REF:0000096, MGI:MGI:1203930, MGI:MGI:1332340, MGI:MGI:4417868, MGI:MGI:4834177, MGI:MGI:5787847, MGI:MGI:6201960, MGI:MGI:72180 NCBI chr 2:27,165,507...27,183,204
Ensembl chr 2:27,165,233...27,183,200
JBrowse link
G Epas1 endothelial PAS domain protein 1 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr17:86,753,864...86,833,410
Ensembl chr17:86,753,700...86,833,410
JBrowse link
G Gata3 GATA binding protein 3 IMP (MGI:MGI:1859081|PMID:10835639) MGI PMID:10835639 MGI:MGI:1859081 NCBI chr 2:9,857,078...9,887,953
Ensembl chr 2:9,857,078...9,890,034
JBrowse link
G Insm1 insulinoma-associated 1 IMP (MGI:MGI:3772428|PMID:18094025) UniProtKB PMID:18094025 MGI:MGI:3772428 NCBI chr 2:146,221,997...146,225,020
Ensembl chr 2:146,221,921...146,225,020
JBrowse link
G Kl klotho ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 5:150,952,607...150,993,817
Ensembl chr 5:150,952,607...150,993,817
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr10:24,223,517...24,302,783
Ensembl chr10:24,223,517...24,302,790
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 6:40,878,794...40,887,494
Ensembl chr 6:40,878,794...40,887,494
JBrowse link
G Th tyrosine hydroxylase ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 7:142,892,779...142,899,995
Ensembl chr 7:142,892,752...142,931,128
JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 IMP (MGI:MGI:4413411|PMID:19008477) BHF-UCL PMID:19008477 MGI:MGI:4413411 NCBI chr 8:57,320,983...57,324,517
Ensembl chr 8:57,320,983...57,324,633
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23392
    metabolic process 11300
      nitrogen compound metabolic process 9371
        organonitrogen compound metabolic process 6264
          catecholamine metabolic process 60
            norepinephrine metabolic process 17
              norepinephrine biosynthetic process + 10
              norepinephrine catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 23392
    metabolic process 11300
      cellular metabolic process 10092
        cellular aromatic compound metabolic process 5437
          phenol-containing compound metabolic process 126
            catechol-containing compound metabolic process 60
              catecholamine metabolic process 60
                norepinephrine metabolic process 17
                  norepinephrine biosynthetic process + 10
                  norepinephrine catabolic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.