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ONTOLOGY REPORT - ANNOTATIONS


Term:norepinephrine metabolic process
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Accession:GO:0042415 term browser browse the term
Definition:The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
Synonyms:exact_synonym: levarterenol metabolic process;   levarterenol metabolism;   noradrenaline metabolic process;   noradrenaline metabolism;   norepinephrine metabolism


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norepinephrine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1B1 aldo-keto reductase family 1 member B IEA Ensembl GO_REF:0000107 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
JBrowse link
G ATP7A ATPase copper transporting alpha ISS UniProtKB GO_REF:0000024 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,656...78,050,395
JBrowse link
G EPAS1 endothelial PAS domain protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G LY6E lymphocyte antigen 6 family member E ISO (MGI:MGI:2157257|PMID:11784869) MGI PMID:11784869 MGI:MGI:2157257 NCBI chr 8:143,018,529...143,022,409
Ensembl chr 8:143,017,982...143,023,832
JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:3945626 RGD:5130757 NCBI chr17:39,668,019...39,670,475
Ensembl chr17:39,667,981...39,670,475
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase IEA Ensembl GO_REF:0000107 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,771
Ensembl chr 6:161,347,417...162,727,771
JBrowse link
G RNF180 ring finger protein 180 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:64,165,311...64,372,879
Ensembl chr 5:64,165,843...64,372,869
JBrowse link
G RTL4 retrotransposon Gag like 4 IEA Ensembl GO_REF:0000107 NCBI chr  X:112,083,025...112,457,245
Ensembl chr  X:112,454,500...112,457,112
JBrowse link
G SPR sepiapterin reductase ISO (MGI:MGI:3722569|PMID:16532389) MGI PMID:16532389 MGI:MGI:3722569 NCBI chr 2:72,887,408...72,892,158
Ensembl chr 2:72,887,382...72,892,158
JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO (MGI:MGI:53940|PMID:4858102)
(MGI:MGI:53801|PMID:4405722)
MGI PMID:4405722, PMID:4858102 MGI:MGI:53801, MGI:MGI:53940 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,656...78,050,395
JBrowse link
G DBH dopamine beta-hydroxylase IEA
IBA
IMP
(PMID:21873635)
(PMID:27148966)
UniProtKB
GO_Central
PMID:21873635, PMID:27148966 GO_REF:0000041 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G GATA3 GATA binding protein 3 ISS UniProtKB GO_REF:0000024 NCBI chr10:8,045,420...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G INSM1 INSM transcriptional repressor 1 ISS UniProtKB GO_REF:0000024 NCBI chr20:20,368,104...20,370,949
Ensembl chr20:20,368,104...20,370,949
JBrowse link
G KL klotho ISO RGD PMID:20086041 RGD:10403068 NCBI chr13:33,016,063...33,066,143
Ensembl chr13:33,016,423...33,066,143
JBrowse link
G MOXD1 monooxygenase DBH like 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:132,296,055...132,401,520
Ensembl chr 6:132,296,055...132,401,475
JBrowse link
G MOXD2P monooxygenase DBH like 2, pseudogene IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:142,240,737...142,247,067
Ensembl chr 7:142,240,740...142,247,067
JBrowse link
G TH tyrosine hydroxylase IDA (PMID:12457228) BHF-UCL PMID:12457228 NCBI chr11:2,163,929...2,174,081
Ensembl chr11:2,163,929...2,171,877
Ensembl chr11:2,163,929...2,171,877
JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAND2 heart and neural crest derivatives expressed 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 4:173,526,091...173,530,229
Ensembl chr 4:173,524,969...173,530,229
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12301
      nitrogen compound metabolic process 10489
        organonitrogen compound metabolic process 7158
          catecholamine metabolic process 66
            norepinephrine metabolic process 17
              norepinephrine biosynthetic process + 10
              norepinephrine catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12301
      cellular metabolic process 11283
        cellular aromatic compound metabolic process 6234
          phenol-containing compound metabolic process 132
            catechol-containing compound metabolic process 66
              catecholamine metabolic process 66
                norepinephrine metabolic process 17
                  norepinephrine biosynthetic process + 10
                  norepinephrine catabolic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.