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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular biogenic amine catabolic process
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Accession:GO:0042402 term browser browse the term
Definition:The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
Synonyms:exact_synonym: biogenic amine breakdown;   biogenic amine catabolism;   biogenic amine degradation


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catecholamine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11559542), (PMID:15645182), (PMID:21846718)
UniProt
RGD
PMID:11559542, PMID:15645182, PMID:21846718, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing ISS
ISO
IBA
GO_REF:0000024
(MGI:3799635|PMID:18794526)
PMID:21873635
UniProt
RGD
PMID:18794526, PMID:21873635 GO_REF:0000024, MGI:3799635, RGD:13792537 NCBI chr 1:166,985,468...166,989,681
Ensembl chr 1:166,986,013...166,988,062
JBrowse link
G Maoa monoamine oxidase A NAS RGD PMID:12388421 RGD:629546 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
choline catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase TAS
ISO
IEA
(PMID:10102904)
GO_REF:0000107
RGD
Ensembl
PMID:10102904, PMID:1710985 GO_REF:0000107, RGD:632576 NCBI chr 2:23,289,376...23,370,360
Ensembl chr 2:23,289,374...23,370,477
JBrowse link
G Sardh sarcosine dehydrogenase TAS
NAS
PMID:9839943 RGD
UniProt
PMID:9839943, PMID:9839943 RGD:634034, RGD:634034 NCBI chr 3:5,737,203...5,802,153
Ensembl chr 3:5,737,200...5,802,129
JBrowse link
dopamine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase ISO (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Dbh dopamine beta-hydroxylase IEA
ISO
IBA
ISS
GO_REF:0000107
MGI:1857556 (MGI:1332340|PMID:10051631), (MGI:5787847|PMID:27148966), (MGI:72180|PMID:7715704)
PMID:21873635
(PMID:3443096), (PMID:7961964)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:3443096, PMID:7715704, PMID:7961964, PMID:10051631, PMID:27148966, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:1332340, MGI:5787847, MGI:72180, RGD:13792537 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Maoa monoamine oxidase A IEA
ISO
GO_REF:0000107
(MGI:2386819|PMID:9520487)
Ensembl
RGD
PMID:9520487 GO_REF:0000107, MGI:2386819 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,124,498...22,206,565
Ensembl chr 1:22,124,495...22,206,505
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO MGI:2386303 (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
histamine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase ISO
ISS
(PMID:26206890)
GO_REF:0000024
RGD
UniProt
PMID:26206890 GO_REF:0000024 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
polyamine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase IDA
ISO
(MGI:2663545|PMID:12660232)
(PMID:12477380)
RGD PMID:12477380, PMID:12660232, PMID:15541750 MGI:2663545, RGD:7244190 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA RGD PMID:15541750 RGD:7244190 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Smox spermine oxidase ISO (PMID:12477380) RGD PMID:12477380 NCBI chr 3:124,068,796...124,103,726
Ensembl chr 3:124,068,865...124,102,240
JBrowse link
putrescine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase IDA
ISO
PMID:16354669
(PMID:16354669)
RGD PMID:16354669, PMID:16354669 RGD:12790650 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
spermidine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase IDA RGD PMID:7721768 RGD:2316236 NCBI chr19:26,184,665...26,188,755
Ensembl chr19:26,184,545...26,188,832
JBrowse link
G Paox polyamine oxidase IDA
ISO
(PMID:16354669) RGD PMID:16354669, PMID:7560898, PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
spermine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase IDA
ISO
PMID:16354669
(PMID:16354669)
RGD PMID:16354669, PMID:7560898, PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
G Smox spermine oxidase IDA
ISO
(MGI:2429361|PMID:12141946)
(PMID:18422650)
RGD PMID:12141946, PMID:18422650, PMID:15541750 MGI:2429361, RGD:7244190 NCBI chr 3:124,068,796...124,103,726
Ensembl chr 3:124,068,865...124,102,240
JBrowse link
tryptophan catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase IDA RGD PMID:11802786 RGD:70243 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase ISO (PMID:17334708) RGD PMID:17334708 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase IDA RGD PMID:7236232 RGD:2303721 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7236232, PMID:21873635 RGD:2303721, RGD:13792537 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IEA
ISO
IBA
GO_REF:0000041
(MGI:3587527|PMID:15866519)
PMID:21873635
UniProt
RGD
PMID:15866519, PMID:21873635 GO_REF:0000041, MGI:3587527, RGD:13792537 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IDA
ISO
IBA
IEA
(MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:2419335, PMID:11751753, PMID:10719243, PMID:21873635, PMID:11513477 GO_REF:0000107, MGI:2151782, MGI:2156954, RGD:2290190, RGD:13792537, RGD:2290543 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IEA
ISO
IBA
GO_REF:0000041
(MGI:3712725|PMID:17499941), (MGI:3719924|PMID:17671174)
PMID:21873635
(PMID:17671174)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17499941, PMID:17671174, PMID:21873635 GO_REF:0000041, GO_REF:0000107, MGI:3712725, MGI:3719924, RGD:13792537 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Kynu kynureninase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:27762317)
UniProt
RGD
PMID:27762317 GO_REF:0000024, GO_REF:0000041 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      nitrogen compound metabolic process 10347
        organonitrogen compound metabolic process 7134
          amine metabolic process 121
            amine catabolic process 23
              cellular biogenic amine catabolic process 22
                catecholamine catabolic process + 7
                choline catabolic process 2
                ethanolamine catabolic process 0
                histamine catabolic process 1
                indolalkylamine catabolic process + 8
                nicotianamine catabolic process 0
                octopamine catabolic process 0
                phenylethylamine catabolic process 0
                polyamine catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      organic substance metabolic process 11643
        organonitrogen compound metabolic process 7134
          amine metabolic process 121
            cellular amine metabolic process 113
              cellular biogenic amine metabolic process 100
                cellular biogenic amine catabolic process 22
                  catecholamine catabolic process + 7
                  choline catabolic process 2
                  ethanolamine catabolic process 0
                  histamine catabolic process 1
                  indolalkylamine catabolic process + 8
                  nicotianamine catabolic process 0
                  octopamine catabolic process 0
                  phenylethylamine catabolic process 0
                  polyamine catabolic process + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.