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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular biogenic amine catabolic process
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Accession:GO:0042402 term browser browse the term
Definition:The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
Synonyms:exact_synonym: biogenic amine breakdown;   biogenic amine catabolism;   biogenic amine degradation


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catecholamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11559542), (PMID:15645182), (PMID:21846718)
UniProt
RGD
PMID:11559542 PMID:15645182 PMID:21846718 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3799635|PMID:18794526)
PMID:21873635
UniProt
RGD
PMID:18794526 PMID:21873635 GO_REF:0000024 MGI:3799635, RGD:13792537 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704
JBrowse link
G Maoa monoamine oxidase A NAS RGD PMID:12388421 RGD:629546 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
choline catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase involved_in TAS
ISO
IEA
(PMID:10102904)
GO_REF:0000107
RGD
Ensembl
PMID:10102904 PMID:1710985 GO_REF:0000107, RGD:632576 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528
JBrowse link
G Sardh sarcosine dehydrogenase involved_in TAS
NAS
PMID:9839943 RGD
UniProt
PMID:9839943 PMID:9839943 RGD:634034, RGD:634034 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874
JBrowse link
dopamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
ISS
(PMID:3443096), (PMID:7961964)
(MGI:5787847|PMID:27148966), (MGI:72180|PMID:7715704)
MGI:1857556 (MGI:1332340|PMID:10051631)
PMID:21873635
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:3443096 PMID:7715704 PMID:7961964 PMID:10051631 PMID:27148966 More... GO_REF:0000024 GO_REF:0000107 MGI:1332340 MGI:5787847 MGI:72180, RGD:13792537 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Maoa monoamine oxidase A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2386819|PMID:9520487)
Ensembl
RGD
PMID:9520487 GO_REF:0000107 MGI:2386819 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299
JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
histamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase involved_in ISO
ISS
(PMID:26206890)
GO_REF:0000024
RGD
UniProt
PMID:26206890 GO_REF:0000024 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
polyamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:2663545|PMID:12660232)
(PMID:12477380)
RGD PMID:12477380 PMID:12660232 PMID:15541750 MGI:2663545, RGD:7244190 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA RGD PMID:15541750 RGD:7244190 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Smox spermine oxidase involved_in ISO (PMID:12477380) RGD PMID:12477380 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
putrescine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase involved_in ISO
IDA
(PMID:16354669) RGD PMID:16354669 PMID:16354669 RGD:12790650 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
spermidine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase IDA RGD PMID:7721768 RGD:2316236 NCBI chr19:23,082,454...23,086,544
Ensembl chr19:23,082,448...23,086,881
JBrowse link
G Paox polyamine oxidase involved_in IDA
ISO
PMID:16354669
(PMID:16354669)
RGD PMID:16354669 PMID:7560898 PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
spermine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase involved_in IDA
ISO
(PMID:16354669) RGD PMID:16354669 PMID:7560898 PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Smox spermine oxidase acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:2429361|PMID:12141946)
(PMID:18422650)
RGD PMID:12141946 PMID:18422650 PMID:15541750 MGI:2429361, RGD:7244190 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
tryptophan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase IDA RGD PMID:11802786 RGD:70243 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132), (PMID:25767141) RGD PMID:17356132 PMID:25767141 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kynu kynureninase involved_in ISO (PMID:17334708) RGD PMID:17334708 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase IDA RGD PMID:7236232 RGD:2303721 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7236232 PMID:21873635 RGD:2303721, RGD:13792537 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link
tryptophan catabolic process to indole-3-acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467), (PMID:32866000) RGD PMID:32818467 PMID:32866000 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3587527|PMID:15866519)
GO_REF:0000041
RGD
UniProt
PMID:15866519 PMID:21873635 GO_REF:0000041 MGI:3587527, RGD:13792537 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within
IDA
IEA
ISO
IBA
GO_REF:0000002
(MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753)
PMID:21873635
InterPro
RGD
PMID:2419335 PMID:11751753 PMID:10719243 PMID:21873635 PMID:11513477 GO_REF:0000002 MGI:2151782 MGI:2156954, RGD:2290190, RGD:13792537, RGD:2290543 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3712725|PMID:17499941), (MGI:3719924|PMID:17671174)
(PMID:17671174)
GO_REF:0000041
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:17499941 PMID:17671174 PMID:21873635 GO_REF:0000041 GO_REF:0000107 MGI:3712725 MGI:3719924, RGD:13792537 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Kynu kynureninase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:27762317)
GO_REF:0000041
UniProt
RGD
PMID:27762317 GO_REF:0000024 GO_REF:0000041 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      nitrogen compound metabolic process 9982
        organonitrogen compound metabolic process 6802
          amine metabolic process 125
            amine catabolic process 24
              cellular biogenic amine catabolic process 23
                catecholamine catabolic process + 7
                choline catabolic process 2
                ethanolamine catabolic process 0
                histamine catabolic process 1
                indolalkylamine catabolic process + 9
                nicotianamine catabolic process 0
                octopamine catabolic process 0
                phenylethylamine catabolic process 0
                polyamine catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      organic substance metabolic process 11337
        organonitrogen compound metabolic process 6802
          amine metabolic process 125
            cellular amine metabolic process 117
              cellular biogenic amine metabolic process 104
                cellular biogenic amine catabolic process 23
                  catecholamine catabolic process + 7
                  choline catabolic process 2
                  ethanolamine catabolic process 0
                  histamine catabolic process 1
                  indolalkylamine catabolic process + 9
                  nicotianamine catabolic process 0
                  octopamine catabolic process 0
                  phenylethylamine catabolic process 0
                  polyamine catabolic process + 4
paths to the root