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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular modified amino acid biosynthetic process
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Accession:GO:0042398 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.
Synonyms:exact_synonym: amino acid derivative biosynthetic process;   cellular amino acid derivative anabolism;   cellular amino acid derivative biosynthesis;   cellular amino acid derivative biosynthetic process;   cellular amino acid derivative formation;   cellular amino acid derivative synthesis;   cellular modified amino acid anabolism;   cellular modified amino acid biosynthesis;   cellular modified amino acid formation;   cellular modified amino acid synthesis


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10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISS
IEA
IDA
(PMID:1881876) BHF-UCL
Ensembl
PMID:1881876 GO_REF:0000024, GO_REF:0000107 NCBI chr14:64,388,353...64,460,025
Ensembl chr14:64,388,031...64,463,457
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like IDA (PMID:12937168) BHF-UCL PMID:12937168 NCBI chr 6:150,865,684...151,101,887
Ensembl chr 6:150,865,549...151,101,887
JBrowse link
carnitine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADM acyl-CoA dehydrogenase medium chain IMP (PMID:16972171) BHF-UCL PMID:16972171 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,347...75,787,575
JBrowse link
G ALDH9A1 aldehyde dehydrogenase 9 family member A1 TAS
IEA
Reactome
UniProtKB
GO_REF:0000041, Reactome:R-HSA-71262 NCBI chr 1:165,662,212...165,698,663
Ensembl chr 1:165,662,216...165,698,863
JBrowse link
G BBOX1 gamma-butyrobetaine hydroxylase 1 TAS
IBA
IDA
IEA
(PMID:21873635)
(PMID:20599753), (PMID:9753662)
Reactome
GO_Central
UniProtKB
PMID:9753662, PMID:20599753, PMID:21873635 GO_REF:0000041, Reactome:R-HSA-71262 NCBI chr11:27,040,705...27,127,809
Ensembl chr11:27,040,725...27,127,809
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 TAS Reactome Reactome:R-HSA-71262 NCBI chr17:18,327,873...18,363,560
Ensembl chr17:18,327,860...18,363,563
JBrowse link
G TMLHE trimethyllysine hydroxylase, epsilon IDA
IBA
IMP
IEA
TAS
(PMID:15754339)
(PMID:21873635)
(PMID:23092983)
BHF-UCL
GO_Central
UniProtKB
Reactome
PMID:15754339, PMID:21873635, PMID:23092983 GO_REF:0000041, Reactome:R-HSA-71262 NCBI chr  X:155,489,011...155,612,952
Ensembl chr  X:155,489,011...155,719,098
Ensembl chr  X:155,489,011...155,719,098
JBrowse link
creatine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAMT guanidinoacetate N-methyltransferase IDA
IBA
IEA
(PMID:8651275)
(PMID:21873635)
UniProtKB
GO_Central
PMID:8651275, PMID:21873635 GO_REF:0000041 NCBI chr19:1,397,026...1,401,542
Ensembl chr19:1,397,026...1,401,570
JBrowse link
G GATM glycine amidinotransferase IDA
IBA
IEA
(PMID:9218780)
(PMID:21873635)
MGI
GO_Central
UniProtKB
PMID:9218780, PMID:21873635 GO_REF:0000041 NCBI chr15:45,361,124...45,402,227
Ensembl chr15:45,361,124...45,402,327
JBrowse link
folic acid-containing compound biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FPGS folylpolyglutamate synthase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:127,802,858...127,814,520
Ensembl chr 9:127,794,597...127,814,327
JBrowse link
G MTHFS methenyltetrahydrofolate synthetase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:79,843,547...79,897,285
Ensembl chr15:79,833,585...79,897,379
JBrowse link
glutathione biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 TAS Reactome Reactome:R-HSA-174403 NCBI chr15:40,942,137...40,956,518
Ensembl chr15:40,952,962...40,956,512
JBrowse link
G CHAC2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 TAS Reactome Reactome:R-HSA-174403 NCBI chr 2:53,767,783...53,775,196
Ensembl chr 2:53,767,804...53,775,196
JBrowse link
G CNDP2 carnosine dipeptidase 2 TAS Reactome Reactome:R-HSA-174403 NCBI chr18:74,496,363...74,523,454
Ensembl chr18:74,495,816...74,523,454
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit IEA
IBA
IDA
TAS
IMP
(PMID:21873635)
(PMID:10395918), (PMID:8104187), (PMID:9675072)
(PMID:12663448)
InterPro
GO_Central
UniProt
Reactome
UniProtKB
PMID:8104187, PMID:9675072, PMID:10395918, PMID:12663448, PMID:21873635 GO_REF:0000002, GO_REF:0000041, Reactome:R-HSA-174403 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit IEA
IBA
IDA
TAS
IMP
(PMID:21873635)
(PMID:10395918), (PMID:9675072)
(PMID:12081989)
UniProtKB
GO_Central
UniProt
Reactome
PMID:9675072, PMID:10395918, PMID:12081989, PMID:21873635 GO_REF:0000041, Reactome:R-HSA-174403 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GGCT gamma-glutamylcyclotransferase TAS Reactome Reactome:R-HSA-174403 NCBI chr 7:30,496,621...30,504,829
Ensembl chr 7:30,496,621...30,504,841
JBrowse link
G GGT1 gamma-glutamyltransferase 1 TAS
ISS
Reactome
UniProtKB
GO_REF:0000024, Reactome:R-HSA-174403 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,556,007...24,628,987
Ensembl chr22:24,556,007...24,628,987
Ensembl chr22:24,556,007...24,628,987
JBrowse link
G GGT3P gamma-glutamyltransferase 3 pseudogene IEA UniProt GO_REF:0000043 NCBI chr22:18,773,689...18,791,961
Ensembl chr22:18,773,665...18,843,399
JBrowse link
G GGT5 gamma-glutamyltransferase 5 IEA UniProt GO_REF:0000043 NCBI chr22:24,219,654...24,245,142
Ensembl chr22:24,219,654...24,245,142
JBrowse link
G GGT6 gamma-glutamyltransferase 6 IEA UniProt GO_REF:0000043 NCBI chr17:4,556,927...4,560,920
Ensembl chr17:4,556,927...4,560,818
JBrowse link
G GGT7 gamma-glutamyltransferase 7 IEA UniProt GO_REF:0000043 NCBI chr20:34,844,720...34,872,857
Ensembl chr20:34,844,720...34,872,856
JBrowse link
G GSS glutathione synthetase TAS
IEA
Reactome
InterPro
GOC
UniProtKB
GO_REF:0000002, GO_REF:0000041, GO_REF:0000108, Reactome:R-HSA-174403 NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027
JBrowse link
G HAGH hydroxyacylglutathione hydrolase IDA (PMID:8550579) UniProtKB PMID:8550579 NCBI chr16:1,807,629...1,827,194
Ensembl chr16:1,795,620...1,827,157
JBrowse link
G MGST2 microsomal glutathione S-transferase 2 IDA (PMID:8703034) UniProtKB PMID:8703034 NCBI chr 4:139,665,725...139,754,608
Ensembl chr 4:139,665,768...139,740,745
JBrowse link
G OPLAH 5-oxoprolinase, ATP-hydrolysing TAS Reactome Reactome:R-HSA-174403 NCBI chr 8:144,051,266...144,064,026
Ensembl chr 8:144,051,266...144,063,965
JBrowse link
glycine betaine biosynthetic process from choline term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 IEA UniProtKB GO_REF:0000041 NCBI chr 5:126,541,841...126,595,219
Ensembl chr 5:126,531,200...126,595,362
JBrowse link
G CHDH choline dehydrogenase IEA UniProtKB GO_REF:0000041 NCBI chr 3:53,812,335...53,846,464
Ensembl chr 3:53,812,335...53,846,419
JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 IDA (PMID:10934207) CAFA PMID:10934207 NCBI chr 3:146,069,437...146,161,184
Ensembl chr 3:146,069,440...146,163,653
JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 IEA Ensembl GO_REF:0000107 NCBI chr 7:101,205,984...101,217,581
Ensembl chr 7:101,205,977...101,218,420
JBrowse link
phosphatidylserine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLSCR1 phospholipid scramblase 1 ISS UniProtKB GO_REF:0000024 NCBI chr 3:146,515,178...146,544,805
Ensembl chr 3:146,515,180...146,544,856
JBrowse link
G PTDSS1 phosphatidylserine synthase 1 TAS
IDA
IEA
(PMID:19014349) Reactome
FlyBase
UniProtKB
PMID:19014349 GO_REF:0000041, Reactome:R-HSA-1483101 NCBI chr 8:96,261,902...96,336,995
Ensembl chr 8:96,261,902...96,336,995
JBrowse link
G PTDSS2 phosphatidylserine synthase 2 TAS
IDA
IEA
(PMID:19014349) Reactome
FlyBase
UniProtKB
PMID:19014349 GO_REF:0000041, Reactome:R-HSA-1483101 NCBI chr11:448,215...491,399
Ensembl chr11:448,268...491,399
JBrowse link
G SLC27A1 solute carrier family 27 member 1 IMP
IBA
(PMID:19523918)
(PMID:21873635)
UniProtKB
GO_Central
PMID:19523918, PMID:21873635 NCBI chr19:17,468,745...17,506,169
Ensembl chr19:17,468,769...17,506,168
JBrowse link
phosphocreatine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CKB creatine kinase B IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr14:103,519,667...103,522,833
Ensembl chr14:103,519,667...103,522,833
JBrowse link
G CKM creatine kinase, M-type IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:45,306,413...45,322,875
Ensembl chr19:45,306,413...45,322,875
JBrowse link
G CKMT1A creatine kinase, mitochondrial 1A IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr15:43,692,644...43,699,222
Ensembl chr15:43,692,886...43,699,222
JBrowse link
G CKMT1B creatine kinase, mitochondrial 1B IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr15:43,592,857...43,599,406
Ensembl chr15:43,593,054...43,604,901
JBrowse link
G CKMT2 creatine kinase, mitochondrial 2 IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 5:81,233,322...81,266,398
Ensembl chr 5:81,233,320...81,266,398
JBrowse link
positive regulation of glutathione biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:5616326|PMID:14978030) ParkinsonsUK-UCL PMID:14978030 MGI:5616326 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,627,464
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase IMP (PMID:16731528) ParkinsonsUK-UCL PMID:16731528 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
regulation of glutathione biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC7A11 solute carrier family 7 member 11 IEA Ensembl GO_REF:0000107 NCBI chr 4:138,164,097...138,242,349
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
tetrahydrofolate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase IEA Ensembl GO_REF:0000107 NCBI chr 2:215,311,974...215,359,745
Ensembl chr 2:215,311,956...215,349,773
JBrowse link
G DHFR dihydrofolate reductase IDA
IBA
IEA
(PMID:2303423)
(PMID:21873635)
BHF-UCL
GO_Central
UniProtKB
InterPro
PMID:2303423, PMID:21873635 GO_REF:0000002, GO_REF:0000041 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983
JBrowse link
G DHFR2 dihydrofolate reductase 2 IEA
IBA
(PMID:21873635) InterPro
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000002, GO_REF:0000041 NCBI chr 3:94,057,922...94,063,389
Ensembl chr 3:94,047,836...94,063,389
JBrowse link
G DHFRP1 dihydrofolate reductase pseudogene 1 IDA
IBA
IEA
(PMID:2303423)
(PMID:21873635)
BHF-UCL
GO_Central
UniProtKB
PMID:2303423, PMID:21873635 GO_REF:0000041 NCBI chr18:26,167,862...26,171,357
Ensembl chr18:26,170,726...26,171,284
JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase IEA Ensembl GO_REF:0000107 NCBI chr21:33,503,931...33,542,892
Ensembl chr21:33,503,931...33,543,491
JBrowse link
G GCH1 GTP cyclohydrolase 1 IEA InterPro GO_REF:0000002 NCBI chr14:54,842,016...54,902,826
Ensembl chr14:54,842,008...54,902,826
JBrowse link
tetrahydrofolylpolyglutamate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FPGS folylpolyglutamate synthase IEA
IBA
IDA
(PMID:21873635)
(PMID:25164808), (PMID:3619447)
UniProtKB
GO_Central
BHF-UCL
PMID:3619447, PMID:21873635, PMID:25164808 GO_REF:0000041 NCBI chr 9:127,802,858...127,814,520
Ensembl chr 9:127,794,597...127,814,327
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 18672
    metabolic process 12302
      nitrogen compound metabolic process 10481
        organonitrogen compound metabolic process 7150
          organonitrogen compound biosynthetic process 1846
            cellular modified amino acid biosynthetic process 49
              (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine 0
              4-hydroxyproline biosynthetic process 0
              L-dopa biosynthetic process + 1
              O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process 0
              S-methylmethionine biosynthetic process 0
              aerobactin biosynthetic process 0
              amino-acid betaine biosynthetic process + 7
              cellular modified histidine biosynthetic process + 0
              coenzyme B biosynthetic process 0
              creatine biosynthetic process 2
              folic acid-containing compound biosynthetic process + 10
              glutathione biosynthetic process + 18
              hydroxylysine biosynthetic process 2
              lincomycin biosynthetic process 0
              ochratoxin A biosynthetic process 0
              pantothenate biosynthetic process 0
              peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine + 0
              peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine 0
              phosphagen biosynthetic process + 5
              phosphatidylserine biosynthetic process + 4
              prenylcysteine biosynthetic process 0
              pyrrolysine biosynthetic process 0
              sarcosine biosynthetic process 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.