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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular modified amino acid biosynthetic process
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Accession:GO:0042398 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.
Synonyms:exact_synonym: amino acid derivative biosynthetic process;   cellular amino acid derivative anabolism;   cellular amino acid derivative biosynthesis;   cellular amino acid derivative biosynthetic process;   cellular amino acid derivative formation;   cellular amino acid derivative synthesis;   cellular modified amino acid anabolism;   cellular modified amino acid biosynthesis;   cellular modified amino acid formation;   cellular modified amino acid synthesis


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10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)
BHF-UCL PMID:1881876, PMID:23704330 MGI:5503248 NCBI chr 8:38,831,672...38,889,607
Ensembl chr 8:38,831,860...38,889,453
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like ISO (PMID:12937168) BHF-UCL PMID:12937168 NCBI chr 1:41,316,247...41,495,226
Ensembl chr 1:41,309,419...41,495,216
JBrowse link
carnitine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADM acyl-CoA dehydrogenase medium chain ISO (PMID:16972171) BHF-UCL PMID:16972171 NCBI chr 6:70,852,223...70,881,979
Ensembl chr 6:70,853,061...70,878,668
JBrowse link
G BBOX1 gamma-butyrobetaine hydroxylase 1 IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr21:47,707,648...47,766,732
Ensembl chr21:47,706,717...47,766,503
JBrowse link
G TMLHE trimethyllysine hydroxylase, epsilon IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr  X:123,322,773...123,438,999
Ensembl chr  X:123,324,729...123,438,947
JBrowse link
creatine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAMT guanidinoacetate N-methyltransferase ISO (PMID:8651275)
(MGI:3043413|PMID:15028668)
UniProtKB
MGI
RGD
PMID:8651275, PMID:15028668, PMID:15533043 MGI:3043413, RGD:1359081 NCBI chr20:57,440,698...57,442,588 JBrowse link
G GATM glycine amidinotransferase IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr30:11,724,446...11,742,214
Ensembl chr30:11,723,519...11,742,214
JBrowse link
G SBNO2 strawberry notch homolog 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:57,592,901...57,640,047
Ensembl chr20:57,267,724...57,640,750
JBrowse link
folic acid-containing compound biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FPGS folylpolyglutamate synthase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:55,590,092...55,612,639
Ensembl chr 9:55,585,970...55,599,028
JBrowse link
G MTHFS methenyltetrahydrofolate synthetase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:57,480,935...57,514,836 JBrowse link
glutathione biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCLC glutamate-cysteine ligase catalytic subunit IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr12:20,999,815...21,047,779
Ensembl chr12:21,000,792...21,047,779
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit ISO (PMID:12081989)
(MGI:3607629|PMID:16081425)
(PMID:10395918), (PMID:9675072)
UniProtKB
MGI
UniProt
RGD
PMID:9675072, PMID:10395918, PMID:12081989, PMID:16081425, PMID:16183645 MGI:3607629, RGD:1582661 NCBI chr 6:55,204,602...55,244,217 JBrowse link
G GGT1 gamma-glutamyltransferase 1 IEA Ensembl GO_REF:0000107 NCBI chr26:28,301,455...28,315,029 JBrowse link
G GGT7 gamma-glutamyltransferase 7 IEA UniProt GO_REF:0000041 NCBI chr24:23,900,842...23,924,555
Ensembl chr24:23,901,045...23,997,286
JBrowse link
G GSS glutathione synthetase IEA UniProtKB GO_REF:0000041 NCBI chr24:23,973,807...24,000,281
Ensembl chr24:23,901,045...23,997,286
JBrowse link
G HAGH hydroxyacylglutathione hydrolase ISO (PMID:8550579) UniProtKB PMID:8550579 NCBI chr 6:39,076,364...39,105,646
Ensembl chr 6:39,084,513...39,105,592
JBrowse link
G MGST2 microsomal glutathione S-transferase 2 ISO (PMID:8703034) UniProtKB PMID:8703034 NCBI chr19:3,067,062...3,070,579 JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 IEA Ensembl GO_REF:0000107 NCBI chr23:41,290,183...41,382,917
Ensembl chr23:41,290,567...41,382,807
JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 IEA Ensembl GO_REF:0000107 NCBI chr 6:8,664,135...8,671,637
Ensembl chr 6:8,664,358...8,671,620
JBrowse link
phosphatidylserine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC611500 phospholipid scramblase 1 ISO (MGI:5284813|PMID:12509439) UniProt PMID:12509439 MGI:5284813 NCBI chr23:41,639,938...41,668,972
Ensembl chr23:41,599,843...41,669,112
JBrowse link
G PTDSS1 phosphatidylserine synthase 1 IEA UniProt GO_REF:0000041 NCBI chr29:40,747,840...40,819,162
Ensembl chr29:40,768,237...40,925,800
JBrowse link
G PTDSS2 phosphatidylserine synthase 2 IEA UniProt GO_REF:0000041 NCBI chr18:25,583,916...25,604,779
Ensembl chr18:25,583,088...25,604,213
JBrowse link
G SLC27A1 solute carrier family 27 member 1 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr20:45,309,094...45,341,101
Ensembl chr20:45,310,088...45,340,230
JBrowse link
phosphocreatine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CKB creatine kinase B IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 8:71,284,104...71,287,379 JBrowse link
G CKM creatine kinase, M-type IEA
IBA
(PMID:21873635) Ensembl
GO_Central
InterPro
PMID:21873635 GO_REF:0000002, GO_REF:0000107 NCBI chr 1:110,210,158...110,218,937
Ensembl chr 1:110,210,152...110,343,383
JBrowse link
G CKMT1A creatine kinase, mitochondrial 1A IEA InterPro GO_REF:0000002 NCBI chr30:10,438,566...10,444,532 JBrowse link
G CKMT2 creatine kinase, mitochondrial 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:26,011,261...26,042,646
Ensembl chr 3:26,011,263...26,026,991
JBrowse link
G LOC476334 creatine kinase, brain pseudogene IEA InterPro GO_REF:0000002 NCBI chr 1:90,101,443...90,102,790 JBrowse link
positive regulation of glutathione biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:5616326|PMID:14978030) ParkinsonsUK-UCL PMID:14978030 MGI:5616326 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 IEA Ensembl GO_REF:0000107 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524
JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase ISO (PMID:16731528) ParkinsonsUK-UCL PMID:16731528 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303
JBrowse link
regulation of glutathione biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC7A11 solute carrier family 7 member 11 IEA Ensembl GO_REF:0000107 NCBI chr19:4,289,792...4,379,060
Ensembl chr19:4,289,850...4,389,048
JBrowse link
tetrahydrofolate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO RGD PMID:7057182 RGD:2301991 NCBI chr37:22,420,645...22,446,769
Ensembl chr37:22,420,603...22,446,697
JBrowse link
G DHFR dihydrofolate reductase IEA InterPro GO_REF:0000002 NCBI chr 3:26,521,214...26,556,065 JBrowse link
G GCH1 GTP cyclohydrolase 1 IEA InterPro GO_REF:0000002 NCBI chr 8:30,733,422...30,784,067
Ensembl chr 8:30,732,608...30,784,156
JBrowse link
G LOC487740 trifunctional purine biosynthetic protein adenosine-3 ISO RGD PMID:4078017 RGD:2301990 NCBI chr31:29,032,399...29,063,706 JBrowse link
tetrahydrofolylpolyglutamate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FPGS folylpolyglutamate synthase IEA
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 9:55,590,092...55,612,639
Ensembl chr 9:55,585,970...55,599,028
JBrowse link

Term paths to the root
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  biological_process 16190
    metabolic process 10657
      nitrogen compound metabolic process 8990
        organonitrogen compound metabolic process 6198
          organonitrogen compound biosynthetic process 1578
            cellular modified amino acid biosynthetic process 36
              (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine 0
              4-hydroxyproline biosynthetic process 0
              L-dopa biosynthetic process + 1
              O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process 0
              S-methylmethionine biosynthetic process 0
              aerobactin biosynthetic process 0
              amino-acid betaine biosynthetic process + 3
              cellular modified histidine biosynthetic process + 0
              coenzyme B biosynthetic process 0
              creatine biosynthetic process 3
              folic acid-containing compound biosynthetic process + 8
              glutathione biosynthetic process + 10
              hydroxylysine biosynthetic process 2
              lincomycin biosynthetic process 0
              ochratoxin A biosynthetic process 0
              pantothenate biosynthetic process 0
              peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine + 0
              peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine 0
              phosphagen biosynthetic process + 5
              phosphatidylserine biosynthetic process + 4
              prenylcysteine biosynthetic process 0
              pyrrolysine biosynthetic process 0
              sarcosine biosynthetic process 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.