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ONTOLOGY REPORT - ANNOTATIONS

Term:vitamin K metabolic process
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Accession:GO:0042373 term browser browse the term
Definition:The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.
Synonyms:exact_synonym: vitamin K metabolism
 broad_synonym: naphthoquinone metabolic process;   naphthoquinone metabolism


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vitamin K metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm2 apoptosis-inducing factor, mitochondrion-associated 2 involved_in ISO
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr10:61,551,042...61,575,474
Ensembl chr10:61,551,042...61,575,039 		JBrowse link
G Cbr1 carbonyl reductase 1 involved_in ISO
ISS		 MGI
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393 		JBrowse link
G Cbr1b carbonyl reductase 1B involved_in ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr16:93,424,872...93,427,351
Ensembl chr16:93,424,985...93,427,339 		JBrowse link
G Ggcx gamma-glutamyl carboxylase involved_in ISO
IEA
IBA		 MGI
Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 involved_in IDA
ISO		 (MGI:85821|PMID:8999809)
(PMID:8999809)		 UniProt
MGI
GO_Central		 PMID:8999809 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 MGI:85821 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA
IDA		 (MGI:5559848|PMID:19492146)
(PMID:19492146)
(PMID:15879509)		 UniProt
GO_Central
MGI		 PMID:15879509 PMID:19492146 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:5559848 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626 		JBrowse link
G Vkorc1l1 vitamin K epoxide reductase complex, subunit 1-like 1 involved_in
acts_upstream_of_or_within		 IDA
ISO
IBA		 (MGI:5559651|PMID:23928358) UniProt
GO_Central
MGI		 PMID:23928358 GO_REF:0000008 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 MGI:5559651 NCBI chr 5:129,970,950...130,015,533
Ensembl chr 5:129,970,811...130,015,533 		JBrowse link
phylloquinone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 ISO menadione catabolism RGD PMID:16359670 RGD:2316273 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393 		JBrowse link
G Cbr3 carbonyl reductase 3 involved_in ISO menadione catabolism RGD
MGI
GO_Central		 PMID:18983987 GO_REF:0000096 MGI:4417868 RGD:2316293 NCBI chr16:93,480,107...93,487,879
Ensembl chr16:93,480,103...93,487,878 		JBrowse link
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 involved_in ISO GO_Central GO_REF:0000119 NCBI chr17:32,877,860...32,895,893
Ensembl chr17:32,877,874...32,895,888 		JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in ISO
IBA
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 4:148,518,952...148,529,217
Ensembl chr 4:148,518,952...148,529,228 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 acts_upstream_of_or_within ISO (PMID:12072400) MGI PMID:12072400 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626 		JBrowse link
vitamin K catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 involved_in ISO GO_Central GO_REF:0000119 NCBI chr17:32,877,860...32,895,893
Ensembl chr17:32,877,874...32,895,888 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28762
    cellular process 18488
      metabolic process 11920
        ketone metabolic process 272
          vitamin K metabolic process 10
            phylloquinone metabolic process + 3
            vitamin K biosynthetic process + 2
            vitamin K catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 28762
    cellular process 18488
      metabolic process 11920
        small molecule metabolic process 1936
          vitamin metabolic process 108
            fat-soluble vitamin metabolic process 41
              vitamin K metabolic process 10
                phylloquinone metabolic process + 3
                vitamin K biosynthetic process + 2
                vitamin K catabolic process + 3
paths to the root