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ONTOLOGY REPORT - ANNOTATIONS


Term:vitamin K metabolic process
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Accession:GO:0042373 term browser browse the term
Definition:The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.
Synonyms:exact_synonym: vitamin K metabolism
 broad_synonym: naphthoquinone metabolic process;   naphthoquinone metabolism



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vitamin K metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 involved_in ISO
ISS
(PMID:18449627)
GO_REF:0000024
RGD
UniProt
PMID:18449627 GO_REF:0000024 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,857,991...32,895,275
JBrowse link
G LOC102556347 carbonyl reductase [NADPH] 1-like involved_in ISO (PMID:18449627) RGD PMID:18449627 NCBI chr11:32,892,640...32,895,277
Ensembl chr11:32,857,991...32,895,275
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
GO_REF:0000024
(MGI:3604816|PMID:15879509)
(MGI:5559848|PMID:19492146)
PMID:21873635
(PMID:16270630)
UniProt
RGD
PMID:15879509 PMID:16270630 PMID:19492146 PMID:21873635 GO_REF:0000024 MGI:3604816 MGI:5559848, RGD:13792537 NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008
JBrowse link
G Vkorc1l1 vitamin K epoxide reductase complex, subunit 1-like 1 involved_in ISO
IDA
IBA
(PMID:21367861)
(MGI:5559651|PMID:23928358)
PMID:21873635
RGD PMID:21367861 PMID:23928358 PMID:23928358 PMID:21873635 MGI:5559651, RGD:8553362, RGD:13792537 NCBI chr12:26,717,959...26,768,193
Ensembl chr12:26,623,976...26,768,225
JBrowse link
phylloquinone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 IDA menadione catabolism RGD PMID:16359670 RGD:2316273 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,857,991...32,895,275
JBrowse link
G Cbr3 carbonyl reductase 3 IDA menadione catabolism RGD PMID:18983987 RGD:2316293 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 involved_in IBA
ISO
PMID:21873635
(PMID:24138531)
RGD PMID:24138531 PMID:21873635 RGD:13792537 NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229
JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:20953171), (PMID:23169578)
UniProt
RGD
PMID:20953171 PMID:23169578 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271
JBrowse link
vitamin K catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 involved_in IBA
ISO
PMID:21873635
(PMID:24138531)
RGD PMID:24138531 PMID:21873635 RGD:13792537 NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      small molecule metabolic process 1829
        vitamin metabolic process 93
          fat-soluble vitamin metabolic process 43
            vitamin K metabolic process 10
              phylloquinone metabolic process + 6
              vitamin K biosynthetic process + 1
              vitamin K catabolic process + 6
paths to the root