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ONTOLOGY REPORT - ANNOTATIONS


Term:vitamin D biosynthetic process
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Accession:GO:0042368 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
Synonyms:exact_synonym: vitamin D anabolism;   vitamin D biosynthesis;   vitamin D formation;   vitamin D synthesis
 narrow_synonym: calciferol biosynthesis;   calciferol biosynthetic process;   cholecalciferol biosynthesis;   cholecalciferol biosynthetic process;   ergocalciferol biosynthesis;   ergocalciferol biosynthetic process



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calcitriol biosynthetic process from calciol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:120,809,886...120,852,196
Ensembl chr15:120,809,959...120,852,193
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:23,053,129...23,058,865
Ensembl chr 5:23,050,114...23,058,470
JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:44,375,432...44,394,122
Ensembl chr 2:44,375,520...44,396,367
JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:23,053,129...23,058,865
Ensembl chr 5:23,050,114...23,058,470
JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:124,619,887...124,629,638
Ensembl chr 4:124,621,258...124,629,639
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,637...118,506,691
JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:51,546,446...51,552,498
Ensembl chr17:51,546,393...51,552,504
JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,878...79,268,475
JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16581
    metabolic process 10424
      organic substance metabolic process 9989
        organic substance biosynthetic process 5192
          organic hydroxy compound biosynthetic process 221
            vitamin D biosynthetic process 9
              calcitriol biosynthetic process from calciol 3
              negative regulation of vitamin D biosynthetic process + 5
              positive regulation of vitamin D biosynthetic process 2
              regulation of vitamin D biosynthetic process + 7
              vitamin D3 biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 16581
    metabolic process 10424
      primary metabolic process 9274
        lipid metabolic process 1225
          steroid metabolic process 280
            steroid biosynthetic process 147
              vitamin D biosynthetic process 9
                calcitriol biosynthetic process from calciol 3
                negative regulation of vitamin D biosynthetic process + 5
                positive regulation of vitamin D biosynthetic process 2
                regulation of vitamin D biosynthetic process + 7
                vitamin D3 biosynthetic process 0
paths to the root