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ONTOLOGY REPORT - ANNOTATIONS

Term:keratan sulfate metabolic process
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Accession:GO:0042339 term browser browse the term
Definition:The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.
Synonyms:exact_synonym: keratan sulfate metabolism;   keratan sulphate metabolic process;   keratan sulphate metabolism


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keratan sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst1 carbohydrate sulfotransferase 1 involved_in ISO
IBA		 (PMID:9405439)
GO_REF:0000033		 RGD
GO_Central		 PMID:9405439 GO_REF:0000033 NCBI chr 3:78,552,059...78,574,740
Ensembl chr 3:78,548,525...78,574,883 		JBrowse link
keratan sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gnt7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 involved_in ISO
ISS		 (PMID:17690104)
(PMID:29625490)
GO_REF:0000024		 RGD
UniProt		 PMID:17690104 PMID:29625490 GO_REF:0000024 NCBI chr 9:86,956,220...86,960,171
Ensembl chr 9:86,956,220...86,960,170 		JBrowse link
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO
ISS		 (PMID:17690104), (PMID:32827291)
GO_REF:0000024		 RGD
UniProt		 PMID:17690104 PMID:32827291 GO_REF:0000024 NCBI chr11:61,995,807...62,021,751
Ensembl chr11:61,995,814...62,021,671 		JBrowse link
G Chst1 carbohydrate sulfotransferase 1 involved_in ISO
ISS		 (PMID:17690104)
GO_REF:0000024		 RGD
UniProt		 PMID:17690104 GO_REF:0000024 NCBI chr 3:78,552,059...78,574,740
Ensembl chr 3:78,548,525...78,574,883 		JBrowse link
G Chst5 carbohydrate sulfotransferase 5 involved_in ISO
IBA		 (PMID:11278593), (PMID:17690104)
GO_REF:0000033		 RGD
GO_Central		 PMID:11278593 PMID:17690104 GO_REF:0000033 NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064 		JBrowse link
keratan sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glb1 galactosidase, beta 1 involved_in ISO
IEA		 (PMID:31720227)
GO_REF:0000107		 RGD
Ensembl		 PMID:31720227 GO_REF:0000107 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Gns glucosamine (N-acetyl)-6-sulfatase IDA RGD PMID:3161730 RGD:1600571 NCBI chr 7:56,889,148...56,923,173
Ensembl chr 7:56,889,232...56,923,151 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        sulfur compound metabolic process 342
          keratan sulfate metabolic process 6
            keratan sulfate biosynthetic process 4
            keratan sulfate catabolic process 2
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        macromolecule metabolic process 9812
          aminoglycan metabolic process 119
            glycosaminoglycan metabolic process 105
              mucopolysaccharide metabolic process 86
                keratan sulfate metabolic process 6
                  keratan sulfate biosynthetic process 4
                  keratan sulfate catabolic process 2
paths to the root