ONTOLOGY REPORT - ANNOTATIONS
Term: vasodilation
Accession: GO:0042311
browse the term
Definition: An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.
Synonyms: exact_synonym: positive regulation of blood vessel size; vasodilatation
alt_id: GO:0045909
xref: Wikipedia:Vasodilation
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Abcc9
ATP binding cassette subfamily C member 9
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:21421823) GO_REF:0000107
RGD Ensembl
PMID:21421823
GO_REF:0000107
NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
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Adcyap1
adenylate cyclase activating polypeptide 1
IDA
RGD
PMID:19220306
RGD:2325268
NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
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Adora1
adenosine A1 receptor
IDA
vasodilation induced by electrical stimulation of the trigeminal nerve
RGD
PMID:12100087
RGD:1625290
NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
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Adora2a
adenosine A2a receptor
IMP
AMPA induced dilation of pial artery in renal medulla
RGD
PMID:16601261 PMID:10070140
RGD:1625442 , RGD:628573
NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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Adora2b
adenosine A2B receptor
involved_in
IDA IBA
GO_REF:0000033
GO_Central RGD
PMID:10666062
GO_REF:0000033, RGD:2316148
NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
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Adra2a
adrenoceptor alpha 2A
IDA
RGD
PMID:20837990
RGD:6480489
NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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Adrb2
adrenoceptor beta 2
IDA
RGD
PMID:15351777
RGD:1598752
NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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Agt
angiotensinogen
IDA
RGD
PMID:21056585 PMID:23718715
RGD:5129196 , RGD:8549478
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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Agtr2
angiotensin II receptor, type 2
involved_in
ISO IMP
(PMID:15117835), (PMID:17159079)
RGD
PMID:15117835 PMID:17159079 PMID:23718715 PMID:18463192
RGD:8549478 , RGD:2313550
NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
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Alb
albumin
NAS
RGD
PMID:11983891
RGD:708312
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Apoe
apolipoprotein E
acts_upstream_of_or_within
ISO
MGI:2137814 (PMID:9826706)
RGD
PMID:9826706
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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Atg5
autophagy related 5
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3050453|MGI:3663625 (PMID:17450150)
Ensembl RGD
PMID:17450150
GO_REF:0000107
NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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Bbs2
Bardet-Biedl syndrome 2
acts_upstream_of_or_within
ISO
MGI:3521669 (PMID:20852044)
RGD
PMID:20852044
NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993
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Bdkrb2
bradykinin receptor B2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1857135 (PMID:11282893) (PMID:4322742), (PMID:6055465)
Ensembl RGD
PMID:4322742 PMID:6055465 PMID:11282893
GO_REF:0000107
NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
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Bloc1s6
biogenesis of lysosomal organelles complex 1 subunit 6
acts_upstream_of_or_within
ISO
MGI:1856982 (PMID:12485443)
RGD
PMID:12485443
NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308
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Calca
calcitonin-related polypeptide alpha
involved_in
IDA ISO
(PMID:3266556)
RGD
PMID:3266556 PMID:12903912
RGD:1598597
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Casr
calcium-sensing receptor
IMP
RGD
PMID:15084499
RGD:1358486
NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
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Cftr
CF transmembrane conductance regulator
IMP IDA
RGD
PMID:16859673 PMID:17596272
RGD:1599593 , RGD:2314621
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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Cps1
carbamoyl-phosphate synthase 1
involved_in
ISO
(PMID:14718356)
RGD
PMID:14718356
NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
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Drd1
dopamine receptor D1
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
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Ednrb
endothelin receptor type B
IMP
RGD
PMID:14678950
RGD:1581832
NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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Egfr
epidermal growth factor receptor
IMP
RGD
PMID:23232926
RGD:7205478
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Esr2
estrogen receptor 2
IMP
RGD
PMID:24440742
RGD:10045880
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Ext1
exostosin glycosyltransferase 1
acts_upstream_of_or_within
ISO
MGI:108050 (PMID:31365577)
RGD
PMID:31365577
NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
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Ext2
exostosin glycosyltransferase 2
acts_upstream_of_or_within
ISO
MGI:894663 (PMID:31365577)
RGD
PMID:31365577
NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059
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F2rl1
F2R like trypsin receptor 1
involved_in acts_upstream_of_or_within_positive_effect
IDA ISO
PMID:12644441 (MGI:5315674|PMID:21859963) (MGI:3530059|PMID:9918574) PMID:11884377
RGD
PMID:9918574 PMID:21859963 PMID:12644441 PMID:11884377
MGI:3530059 MGI:5315674 , RGD:1582293 , RGD:8553406
NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
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Gch1
GTP cyclohydrolase 1
IMP
RGD
PMID:12855421
RGD:1601283
NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
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Gja1
gap junction protein, alpha 1
IMP
RGD
PMID:15301736
RGD:7207818
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Gja5
gap junction protein, alpha 5
IMP
RGD
PMID:16037574
RGD:7207813
NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
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Gper1
G protein-coupled estrogen receptor 1
acts_upstream_of_positive_effect
IDA IMP
PMID:23283935
GO_Central RGD
PMID:23283935 PMID:30354811
RGD:8553898 , RGD:39939000
NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
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Gpx1
glutathione peroxidase 1
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2158814 (PMID:11893559), (PMID:12196344)
Ensembl RGD
PMID:11893559 PMID:12196344
GO_REF:0000107
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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Grk2
G protein-coupled receptor kinase 2
IMP
RGD
PMID:23913704
RGD:13792716
NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
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Ins2
insulin 2
involved_in
ISO
(PMID:14744991)
RGD
PMID:14744991
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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Itga1
integrin subunit alpha 1
IMP
flow-mediated dilation of mesenteric resistance arteries
RGD
PMID:18245559
RGD:2302134
NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238
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Kat2b
lysine acetyltransferase 2B
IDA
RGD
PMID:22859492
RGD:8693759
NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
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Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
acts_upstream_of_or_within
ISO
MGI:2180015 (PMID:11984590), (PMID:17077304), (PMID:24914196)
RGD
PMID:11984590 PMID:17077304 PMID:24914196
NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
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Kcnma1
potassium calcium-activated channel subfamily M alpha 1
acts_upstream_of_or_within involved_in
IMP ISO IBA
MGI:3050114 (PMID:15867178) GO_REF:0000033
RGD GO_Central
PMID:15867178 PMID:23432816
GO_REF:0000033, RGD:10412027
NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198
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Kcnmb1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
IDA
RGD
PMID:23455312
RGD:10412033
NCBI chr10:18,557,510...18,614,824
Ensembl chr10:18,557,904...18,565,798
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Kdr
kinase insert domain receptor
IGI
RGD
PMID:12052848
RGD:2292104
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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Klf2
KLF transcription factor 2
acts_upstream_of
ISO
(PMID:21768538)
RGD
PMID:21768538
NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
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Kng1
kininogen 1
involved_in
IEA ISO
GO_REF:0000043 (PMID:4322742), (PMID:6055465)
UniProt RGD
PMID:4322742 PMID:6055465
GO_REF:0000043
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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Kng1_v1
kininogen 1, variant 1
involved_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
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Kng2
kininogen 2
involved_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
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Kng2l1
kininogen 2-like 1
involved_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr11:77,978,795...78,002,976
Ensembl chr11:77,909,612...78,002,971
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Mir29a
microRNA 29a
IMP
RGD
PMID:29374012
RGD:13702880
NCBI chr 4:59,650,608...59,650,695
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Mir29b1
microRNA 29b-1
IMP
RGD
PMID:29374012
RGD:13702880
NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067
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Mkks
MKKS centrosomal shuttling protein
acts_upstream_of_or_within
ISO
MGI:3526444 (PMID:20852044)
RGD
PMID:20852044
NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162
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Nos1
nitric oxide synthase 1
involved_in
IMP IEA ISO
GO_REF:0000107 (PMID:18048451), (PMID:18391107)
Ensembl RGD
PMID:18048451 PMID:18391107 PMID:17291465
GO_REF:0000107, RGD:1642146
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Nos3
nitric oxide synthase 3
acts_upstream_of_or_within
ISO
(PMID:24141169)
RGD
PMID:24141169
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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Nppa
natriuretic peptide A
involved_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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Npr3
natriuretic peptide receptor 3
IMP
RGD
PMID:17391657
RGD:1642299
NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
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P2rx4
purinergic receptor P2X 4
acts_upstream_of_or_within
ISO
MGI:3612982 (PMID:16327800)
RGD
PMID:16327800
NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
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Pde5a
phosphodiesterase 5A
IEP
RGD
PMID:16545481
RGD:1582534
NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
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Pla2g6
phospholipase A2 group VI
IMP
RGD
PMID:12183647
RGD:6482758
NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
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Plekha7
pleckstrin homology domain containing A7
IMP
RGD
PMID:25136115
RGD:11079199
NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:170,365,135...170,547,775
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Plod3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3620600|MGI:3620601 (PMID:16467571)
Ensembl RGD
PMID:16467571
GO_REF:0000107
NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960
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Ppard
peroxisome proliferator-activated receptor delta
IDA
RGD
PMID:19906781
RGD:2324878
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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Prkg1
protein kinase cGMP-dependent 1
IMP
RGD
PMID:8719784
RGD:7777111
NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
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Ptgdr
prostaglandin D2 receptor
IMP
RGD
PMID:17643322
RGD:2316818
NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
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Ptgis
prostaglandin I2 synthase
acts_upstream_of_or_within
ISO
(PMID:24141169)
RGD
PMID:24141169
NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
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Ptk2
protein tyrosine kinase 2
IMP
RGD
PMID:16195476
RGD:2292597
NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
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Ptprm
protein tyrosine phosphatase, receptor type, M
acts_upstream_of_or_within
ISO
MGI:3575002 (PMID:15706045)
RGD
PMID:15706045
NCBI chr 9:106,639,573...107,343,698
Ensembl chr 9:106,639,573...107,343,698
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Sirt1
sirtuin 1
IMP
RGD
PMID:23826814
RGD:9585662
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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Sod2
superoxide dismutase 2
acts_upstream_of_or_within
ISO
MGI:1857480 (PMID:15637112)
RGD
PMID:15637112
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Tnf
tumor necrosis factor
IMP
RGD
PMID:16284227
RGD:1580206
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Ucn
urocortin
IDA
RGD
PMID:15467262
RGD:1642786
NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
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Vegfa
vascular endothelial growth factor A
acts_upstream_of_or_within
ISO
(PMID:31698979)
RGD
PMID:31698979
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vstm4
V-set and transmembrane domain containing 4
acts_upstream_of_or_within
ISO
(PMID:31698979)
RGD
PMID:31698979
NCBI chr16:8,120,336...8,200,272
Ensembl chr16:8,120,336...8,200,269
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Sod2
superoxide dismutase 2
acts_upstream_of_or_within
ISO
MGI:1857129|MGI:1857480 (PMID:16873728)
RGD
PMID:16873728
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Agtr2
angiotensin II receptor, type 2
acts_upstream_of_or_within
ISO
MGI:1857123 (PMID:10425188)
RGD
PMID:10425188
NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
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G6pd
glucose-6-phosphate dehydrogenase
acts_upstream_of_or_within
ISO
MGI:2182739 (PMID:15998684)
RGD
PMID:15998684
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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Calca
calcitonin-related polypeptide alpha
acts_upstream_of_or_within
ISO
MGI:2445489 (PMID:11717154)
RGD
PMID:11717154
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Adrb1
adrenoceptor beta 1
involved_in acts_upstream_of_or_within
IEA ISO IBA
GO_REF:0000107 MGI:1857120|MGI:87938 (PMID:10358009), (PMID:11641423) GO_REF:0000033
Ensembl RGD GO_Central
PMID:10358009 PMID:11641423
GO_REF:0000033 GO_REF:0000107
NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
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Adrb2
adrenoceptor beta 2
involved_in acts_upstream_of_or_within
IEA ISO IBA
GO_REF:0000107 MGI:1859675|MGI:87937 (PMID:10358009), (PMID:11641423) GO_REF:0000033
Ensembl RGD GO_Central
PMID:10358009 PMID:11641423
GO_REF:0000033 GO_REF:0000107
NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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Adrb3
adrenoceptor beta 3
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 (PMID:10358009)
GO_Central RGD
PMID:10358009
GO_REF:0000033
NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
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Adora2b
adenosine A2B receptor
acts_upstream_of_or_within
ISO
MGI:3773754 (PMID:18340377)
RGD
PMID:18340377
NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
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Gucy1a1
guanylate cyclase 1 soluble subunit alpha 1
acts_upstream_of_or_within
ISO
MGI:3640802 (PMID:16614755)
RGD
PMID:16614755
NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
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Irag1
inositol 1,4,5-triphosphate receptor associated 1
acts_upstream_of_or_within
ISO
MGI:3525059 (PMID:15483626)
RGD
PMID:15483626
NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176
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Kcnma1
potassium calcium-activated channel subfamily M alpha 1
involved_in acts_upstream_of_or_within
ISO
(PMID:25139746) MGI:3050114 (PMID:15867178)
RGD
PMID:15867178 PMID:25139746
NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198
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Prkg1
protein kinase cGMP-dependent 1
acts_upstream_of_or_within
ISO
MGI:2181586 (PMID:15483626)
RGD
PMID:15483626
NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
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Rgs2
regulator of G-protein signaling 2
involved_in
ISO
(MGI:2682081|PMID:14608379)
RGD
PMID:14608379
MGI:2682081
NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
G
Sod1
superoxide dismutase 1
involved_in acts_upstream_of_or_within
ISS ISO
GO_REF:0000024 MGI:1857873 (PMID:12433839), (PMID:14679182)
UniProt RGD
PMID:12433839 PMID:14679182
GO_REF:0000024
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Trpc1
transient receptor potential cation channel, subfamily C, member 1
involved_in
ISO
(PMID:25139746)
RGD
PMID:25139746
NCBI chr 8:96,263,322...96,314,220
Ensembl chr 8:96,263,329...96,314,276
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Trpv4
transient receptor potential cation channel, subfamily V, member 4
involved_in
ISO
(PMID:25139746)
RGD
PMID:25139746
NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
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