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ONTOLOGY REPORT - ANNOTATIONS

Term:ketone biosynthetic process
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Accession:GO:0042181 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
Synonyms:exact_synonym: ketone anabolism;   ketone biosynthesis;   ketone formation;   ketone synthesis


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ketone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coq5 coenzyme Q5, methyltransferase involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr12:41,316,922...41,333,855
Ensembl chr12:41,316,748...41,333,848 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO
IEA 		(PMID:30530497)
GO_REF:0000107 		RGD
Ensembl		 PMID:30530497 GO_REF:0000107 NCBI chr 7:8,733,056...8,738,543
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 5:164,139,714...164,167,777
Ensembl chr 5:158,868,672...158,880,271 		JBrowse link
aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in IMP
IEA
ISO 		PMID:19342457
GO_REF:0000107
(PMID:19342457) 		Ensembl
RGD		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IMP
IBA 		PMID:19342457
GO_REF:0000033 		GO_Central PMID:19342457 GO_REF:0000033, RGD:4891166 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 acts_upstream_of_or_within
involved_in 		IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
(PMID:19342457), (PMID:2256920) 		Ensembl
GO_Central
RGD		 PMID:2256920 PMID:19342457 PMID:11832364 GO_REF:0000033 GO_REF:0000107, RGD:727991 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:1741400), (PMID:19342457), (PMID:2256920), (PMID:23322723)
GO_REF:0000107
(PMID:1686470), (PMID:8645611) 		RGD
Ensembl		 PMID:1686470 PMID:1741400 PMID:2256920 PMID:8645611 PMID:19342457 More... GO_REF:0000107 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
androst-4-ene-3,17-dione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inhba inhibin subunit beta A acts_upstream_of_or_within ISO
IEA 		(PMID:32954300)
GO_REF:0000107 		RGD
Ensembl		 PMID:32954300 GO_REF:0000107 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in IMP
IEA
ISO 		PMID:19342457
GO_REF:0000107
(PMID:19342457) 		Ensembl
RGD		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IMP PMID:19342457 UniProt PMID:19342457 RGD:4891166 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 involved_in ISO (PMID:19342457), (PMID:2022736), (PMID:8506298) RGD PMID:2022736 PMID:8506298 PMID:19342457 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 NOT|involved_in ISO (PMID:9703385)
(PMID:19342457) 		RGD PMID:9703385 PMID:19342457 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
menaquinone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in ISO
IEA
IBA
ISS 		(PMID:23169578)
GO_REF:0000043
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024
GO_REF:0000041 		RGD
UniProt
Ensembl
GO_Central		 PMID:23169578 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:164,139,714...164,167,777
Ensembl chr 5:158,868,672...158,880,271 		JBrowse link
methylglyoxal biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoa aldolase, fructose-bisphosphate A IMP RGD PMID:21890532 RGD:13673877 NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Tpi1 triosephosphate isomerase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:19584291) 		Ensembl
RGD		 PMID:19584291 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP 		(PMID:19342457)
GO_REF:0000107 		RGD
Ensembl		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA 		(PMID:19584291)
GO_REF:0000107 		RGD
Ensembl		 PMID:19584291 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP 		(PMID:19342457)
GO_REF:0000107 		RGD
Ensembl		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) RGD PMID:24530842 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in ISO (PMID:18818293) RGD PMID:18818293 NCBI chr 1:95,694,010...95,699,259
Ensembl chr 1:95,694,010...95,699,259 		JBrowse link
G Ggcx gamma-glutamyl carboxylase involved_in ISO
IEA 		(PMID:25264202)
GO_REF:0000107 		RGD
Ensembl		 PMID:25264202 GO_REF:0000107 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA 		(PMID:12949260)
GO_REF:0000107 		RGD
Ensembl		 PMID:12949260 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO
IEA 		(PMID:16527843)
GO_REF:0000107 		RGD
Ensembl		 PMID:16527843 GO_REF:0000107 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Dab2 DAB adaptor protein 2 IDA RGD PMID:17303656 RGD:7243836 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA 		(PMID:16981135)
GO_REF:0000107 		RGD
Ensembl		 PMID:16981135 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO
IEA 		(PMID:16981135)
GO_REF:0000107 		RGD
Ensembl		 PMID:16981135 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:20133449 RGD:10059648 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
positive regulation of ubiquinone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pptc7 protein phosphatase targeting COQ7 involved_in ISO
IEA 		(PMID:30267671)
GO_REF:0000107 		RGD
Ensembl		 PMID:30267671 GO_REF:0000107 NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339 		JBrowse link
progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IDA RGD PMID:1955079 RGD:1625116 NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:1703300) RGD PMID:1703300 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 acts_upstream_of_or_within ISO
IEA 		MGI:3042568 (PMID:14963026)
GO_REF:0000107 		RGD
Ensembl		 PMID:14963026 GO_REF:0000107 NCBI chr10:83,357,329...83,379,873
Ensembl chr10:83,357,359...83,550,976 		JBrowse link
quinone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdss1 decaprenyl diphosphate synthase subunit 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO
IEA
ISS 		(PMID:29403011)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:29403011 GO_REF:0000024 GO_REF:0000107 NCBI chr11:93,702,382...93,716,059
Ensembl chr11:80,198,153...80,211,657 		JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in ISO
IEA 		(PMID:18628520), (PMID:23132696)
GO_REF:0000107
(PMID:16356929) 		RGD
Ensembl		 PMID:16356929 PMID:18628520 PMID:23132696 GO_REF:0000107 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171 		JBrowse link
regulation of ketone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt5 sirtuin 5 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:24315375) 		UniProt
Ensembl
RGD		 PMID:24315375 GO_REF:0000024 GO_REF:0000107 NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101 		JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G Egr1 early growth response 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:8703054)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:8703054 GO_REF:0000024 GO_REF:0000107 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:23045399 RGD:26884342 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir455 microRNA 455 IDA RGD PMID:23045399 RGD:26884342 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390 		JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:19336506) RGD PMID:19336506 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein involved_in
acts_upstream_of_or_within 		ISS
ISO 		GO_REF:0000024
(PMID:21333348) 		UniProt
RGD		 PMID:21333348 GO_REF:0000024 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 involved_in ISO
IEA 		(PMID:21333348)
GO_REF:0000107 		RGD
Ensembl		 PMID:21333348 GO_REF:0000107 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Gprc6a G protein-coupled receptor, class C, group 6, member A involved_in
acts_upstream_of_or_within 		ISS
ISO
IEA 		GO_REF:0000024
(PMID:21333348)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:21333348 GO_REF:0000024 GO_REF:0000107 NCBI chr20:30,922,106...30,943,412
Ensembl chr20:30,922,106...30,943,412 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:22429315 RGD:7775068 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
regulation of ubiquinone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adck2 aarF domain containing kinase 2 involved_in ISO
IEA 		(PMID:31480808)
GO_REF:0000107 		RGD
Ensembl		 PMID:31480808 GO_REF:0000107 NCBI chr 4:68,348,853...68,362,725
Ensembl chr 4:68,348,864...68,374,608 		JBrowse link
G Pptc7 protein phosphatase targeting COQ7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339 		JBrowse link
testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:16983398) RGD PMID:16983398 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP RGD PMID:19883722 RGD:4145609 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO
IEA 		MGI:2154536 (PMID:9618522)
GO_REF:0000107 		RGD
Ensembl		 PMID:9618522 GO_REF:0000107 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 involved_in IDA
IEA
ISO 		GO_REF:0000107
(PMID:9658408) 		Ensembl
RGD		 PMID:9658408 PMID:8612487 GO_REF:0000107, RGD:728619 NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,009,728...86,011,927 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:16467141 RGD:4889544 NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Inhba inhibin subunit beta A acts_upstream_of_or_within ISO
IEA 		(PMID:32274496)
GO_REF:0000107 		RGD
Ensembl		 PMID:32274496 GO_REF:0000107 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 involved_in ISO
IEA
ISS 		(PMID:10898110)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:10898110 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein IEP RGD PMID:19883722 RGD:4145609 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
ubiquinone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coq2 coenzyme Q2, polyprenyltransferase involved_in
acts_upstream_of_or_within 		IEA
ISO
IBA
ISS 		GO_REF:0000041
GO_REF:0000043
GO_REF:0000104
MGI:7628277 (PMID:38697100)
GO_REF:0000033
SGD:S000005324 (PMID:15153069)
GO_REF:0000024
(PMID:15153069), (PMID:16400613), (PMID:17374725), (PMID:27493029) 		UniProt
RGD
GO_Central		 PMID:15153069 PMID:16400613 PMID:17374725 PMID:27493029 PMID:38697100 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891 		JBrowse link
G Coq3 coenzyme Q3 methyltransferase involved_in IGI
ISO
ISS
IEA 		UniProtKB:P27680 (PMID:10777520), (PMID:38425362)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000117
GO_REF:0000041
GO_REF:0000002
GO_REF:0000043
GO_REF:0000104 		RGD
UniProt
Ensembl
InterPro		 PMID:10777520 PMID:38425362 PMID:8125303 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117, RGD:69814 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607 		JBrowse link
G Coq4 coenzyme Q4 involved_in IEA
ISO
ISS 		GO_REF:0000041
GO_REF:0000043
GO_REF:0000002
GO_REF:0000104
(PMID:30659264), (PMID:38014483), (PMID:38295803), (PMID:38425362)
GO_REF:0000024 		UniProt
InterPro
RGD		 PMID:30659264 PMID:38014483 PMID:38295803 PMID:38425362 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 NCBI chr 3:13,060,054...13,070,502
Ensembl chr 3:13,060,455...13,068,799 		JBrowse link
G Coq5 coenzyme Q5, methyltransferase involved_in IEA
ISO
ISS
IBA 		GO_REF:0000041
GO_REF:0000104
GO_REF:0000107
GO_REF:0000043
UniProtKB:P49017 (PMID:25152161), (PMID:38425362)
GO_REF:0000024
GO_REF:0000033 		UniProt
Ensembl
RGD
GO_Central		 PMID:25152161 PMID:38425362 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr12:41,316,922...41,333,855
Ensembl chr12:41,316,748...41,333,848 		JBrowse link
G Coq6 coenzyme Q6 monooxygenase involved_in IEA
ISO
ISS
IBA 		GO_REF:0000041
(PMID:38425362)
GO_REF:0000104
GO_REF:0000002
GO_REF:0000107
GO_REF:0000024
MGI:6451728 (PMID:30737270)
GO_REF:0000033
GO_REF:0000043 		UniProt
RGD
InterPro
Ensembl
GO_Central		 PMID:30737270 PMID:38425362 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr 6:104,007,814...104,019,888
Ensembl chr 6:104,007,872...104,024,657 		JBrowse link
G Coq7 coenzyme Q7, hydroxylase involved_in
acts_upstream_of_or_within
NOT|acts_upstream_of_or_within 		IGI
IEA
ISO
IBA
ISS 		GO_REF:0000107
GO_REF:0000117
GO_REF:0000043
GO_REF:0000002
GO_REF:0000104
MGI:2158322 (PMID:11716496)
(PMID:28409910), (PMID:38425362)
GO_REF:0000033
MGI:2157003|MGI:2158322 (PMID:11585841), (PMID:11716496)
MGI:2157003 (PMID:19478076)
GO_REF:0000024
GO_REF:0000041 		Ensembl
UniProt
InterPro
RGD
GO_Central		 PMID:11585841 PMID:11716496 PMID:19478076 PMID:28409910 PMID:38425362 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117, RGD:69815 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158 		JBrowse link
G Coq8a coenzyme Q8A involved_in IEA
ISO
IBA
ISS 		GO_REF:0000041
(PMID:25498144), (PMID:27499294), (PMID:38425362)
GO_REF:0000107
GO_REF:0000043
MGI:6359448 (PMID:27499294)
GO_REF:0000033
GO_REF:0000024 		UniProt
RGD
Ensembl
GO_Central		 PMID:25498144 PMID:27499294 PMID:38425362 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431 		JBrowse link
G Coq8b coenzyme Q8B involved_in ISS
ISO
IEA
IBA 		GO_REF:0000024
(PMID:27499294), (PMID:38425362)
GO_REF:0000107
GO_REF:0000033 		UniProt
RGD
Ensembl
GO_Central		 PMID:27499294 PMID:38425362 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:82,525,578...82,549,182
Ensembl chr 1:82,526,568...82,549,180 		JBrowse link
G Coq9 coenzyme Q9 involved_in
acts_upstream_of_or_within 		IEA
ISO
ISS
IBA 		GO_REF:0000041
GO_REF:0000104
GO_REF:0000002
GO_REF:0000043
GO_REF:0000107
MGI:5473628 (PMID:23255162), (PMID:25339443)
(PMID:30661980), (PMID:38425362)
GO_REF:0000024
GO_REF:0000033 		UniProt
InterPro
Ensembl
RGD
GO_Central		 PMID:23255162 PMID:25339443 PMID:30661980 PMID:38425362 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr19:10,166,948...10,179,976
Ensembl chr19:10,166,951...10,179,949 		JBrowse link
G Fdx2 ferredoxin 2 acts_upstream_of_positive_effect
involved_in 		IEA
ISO 		GO_REF:0000107
(PMID:38425362) 		Ensembl
RGD		 PMID:38425362 GO_REF:0000107 NCBI chr 8:27,881,091...27,886,230
Ensembl chr 8:19,604,916...19,609,849 		JBrowse link
G Fdxr ferredoxin reductase acts_upstream_of_positive_effect ISS
ISO 		GO_REF:0000024
(PMID:38425362) 		UniProt
RGD		 PMID:38425362 GO_REF:0000024 NCBI chr10:101,006,845...101,015,582
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:161,345,398...161,374,188
Ensembl chr 4:159,659,242...159,688,018 		JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 involved_in ISO
IEA
IBA 		(PMID:16262699)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:16262699 GO_REF:0000033 GO_REF:0000107 NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730 		JBrowse link
G Pdss2 decaprenyl diphosphate synthase subunit 2 involved_in IEA
ISO
IBA 		GO_REF:0000041
GO_REF:0000043
(PMID:16262699)
GO_REF:0000033 		UniProt
RGD
GO_Central		 PMID:16262699 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708 		JBrowse link
G Rtn4ip1 reticulon 4 interacting protein 1 involved_in ISO (PMID:37884807) RGD PMID:37884807 NCBI chr20:47,382,251...47,422,747
Ensembl chr20:47,382,234...47,422,338 		JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000043
GO_REF:0000041
GO_REF:0000107
(PMID:23374346) 		UniProt
Ensembl
RGD		 PMID:23374346 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:164,139,714...164,167,777
Ensembl chr 5:158,868,672...158,880,271 		JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in ISS
IEA
IBA
ISO 		GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:20953171), (PMID:23169578) 		UniProt
Ensembl
GO_Central
RGD		 PMID:20953171 PMID:23169578 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:164,139,714...164,167,777
Ensembl chr 5:158,868,672...158,880,271 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        ketone metabolic process 255
          ketone biosynthetic process 58
            (+)-camphor biosynthetic process 0
            1,5-anhydro-D-fructose biosynthetic process 0
            11-oxo-beta-amyrin biosynthetic process 0
            DIF-1 biosynthetic process 0
            acetoin biosynthetic process 0
            aldosterone biosynthetic process + 12
            andrastin A biosynthetic process 0
            androst-4-ene-3,17-dione biosynthetic process + 1
            asperfuranone biosynthetic process + 0
            asperthecin biosynthetic process + 0
            aurone biosynthetic process 0
            averantin biosynthetic process 0
            brexanolone biosynthetic process 0
            chalcone biosynthetic process 0
            conidiogenone biosynthetic process 0
            cortisol biosynthetic process + 11
            cspyrone B1 biosynthetic process 0
            daunorubicin biosynthetic process 0
            ecdysteroid biosynthetic process + 0
            ecgonone methyl ester biosynthetic process 0
            emodin biosynthetic process + 0
            endocrocin biosynthetic process + 0
            epothilone biosynthetic process 0
            funalenone biosynthetic process 0
            glycyrrhetinate biosynthetic process 0
            granaticin biosynthetic process 0
            helvolic acid biosynthetic process + 0
            ilicicolin H biosynthetic process 0
            kojic acid biosynthetic process + 0
            menaquinone biosynthetic process 1
            methylglyoxal biosynthetic process 2
            mitomycin C biosynthetic process 0
            monodictyphenone biosynthetic process + 0
            naphtho-gamma-pyrone biosynthetic process + 0
            neosartoricin biosynthetic process + 0
            novofumigatonin biosynthetic process 0
            paraherquonin biosynthetic process 0
            paxilline biosynthetic process 0
            progesterone biosynthetic process + 9
            pyrroloquinoline quinone biosynthetic process 0
            quinone biosynthetic process + 18
            regulation of ketone biosynthetic process + 25
            shamixanthone biosynthetic process 0
            tensidol A biosynthetic process + 0
            tensidol B biosynthetic process + 0
            testosterone biosynthetic process + 16
            tetracenomycin C biosynthetic process 0
            tetracycline biosynthetic process 0
            undecan-2-one biosynthetic process 0
            viridicatumtoxin biosynthetic process 0
            vitamin K biosynthetic process + 1
            vomitoxin biosynthetic process 0
            xanthone-containing compound biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        biosynthetic process 8630
          small molecule biosynthetic process 669
            ketone biosynthetic process 58
              (+)-camphor biosynthetic process 0
              1,5-anhydro-D-fructose biosynthetic process 0
              11-oxo-beta-amyrin biosynthetic process 0
              DIF-1 biosynthetic process 0
              acetoin biosynthetic process 0
              aldosterone biosynthetic process + 12
              andrastin A biosynthetic process 0
              androst-4-ene-3,17-dione biosynthetic process + 1
              asperfuranone biosynthetic process + 0
              asperthecin biosynthetic process + 0
              aurone biosynthetic process 0
              averantin biosynthetic process 0
              brexanolone biosynthetic process 0
              chalcone biosynthetic process 0
              conidiogenone biosynthetic process 0
              cortisol biosynthetic process + 11
              cspyrone B1 biosynthetic process 0
              daunorubicin biosynthetic process 0
              ecdysteroid biosynthetic process + 0
              ecgonone methyl ester biosynthetic process 0
              emodin biosynthetic process + 0
              endocrocin biosynthetic process + 0
              epothilone biosynthetic process 0
              funalenone biosynthetic process 0
              glycyrrhetinate biosynthetic process 0
              granaticin biosynthetic process 0
              helvolic acid biosynthetic process + 0
              ilicicolin H biosynthetic process 0
              kojic acid biosynthetic process + 0
              menaquinone biosynthetic process 1
              methylglyoxal biosynthetic process 2
              mitomycin C biosynthetic process 0
              monodictyphenone biosynthetic process + 0
              naphtho-gamma-pyrone biosynthetic process + 0
              neosartoricin biosynthetic process + 0
              novofumigatonin biosynthetic process 0
              paraherquonin biosynthetic process 0
              paxilline biosynthetic process 0
              progesterone biosynthetic process + 9
              pyrroloquinoline quinone biosynthetic process 0
              quinone biosynthetic process + 18
              regulation of ketone biosynthetic process + 25
              shamixanthone biosynthetic process 0
              tensidol A biosynthetic process + 0
              tensidol B biosynthetic process + 0
              testosterone biosynthetic process + 16
              tetracenomycin C biosynthetic process 0
              tetracycline biosynthetic process 0
              undecan-2-one biosynthetic process 0
              viridicatumtoxin biosynthetic process 0
              vitamin K biosynthetic process + 1
              vomitoxin biosynthetic process 0
              xanthone-containing compound biosynthetic process + 0
paths to the root