Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein catabolic process
go back to main search page
Accession:GO:0042177 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
Synonyms:exact_synonym: down regulation of protein catabolic process;   downregulation of protein catabolic process;   negative regulation of protein breakdown;   negative regulation of protein catabolism;   negative regulation of protein degradation
 narrow_synonym: inhibition of protein catabolic process



show annotations for term's descendants           Sort by:
 
negative regulation of protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC083977.1 novel protein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 8:32,647,202...32,647,390 JBrowse link
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:142,449,649...142,545,009
Ensembl chr 8:142,449,430...142,545,009
JBrowse link
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 acts_upstream_of_or_within IDA (PMID:18374643) MGI PMID:18374643 NCBI chr12:57,723,761...57,742,201
Ensembl chr12:57,723,761...57,742,157
JBrowse link
G AZIN1 antizyme inhibitor 1 involved_in IBA
ISO
IDA
(PMID:21873635)
downregulates antizyme degradation of ODC
(PMID:17900240)
GO_Central
RGD
UniProt
PMID:8631929 PMID:17900240 PMID:21873635 RGD:633334 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,111...102,893,864
JBrowse link
G AZIN2 antizyme inhibitor 2 involved_in IBA
IDA
(PMID:21873635)
(PMID:17900240)
GO_Central
UniProt
PMID:17900240 PMID:21873635 NCBI chr 1:33,081,152...33,162,288
Ensembl chr 1:33,081,104...33,123,492
JBrowse link
G BANP BTG3 associated nuclear protein involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3579758|PMID:15701641)
GO_Central
MGI
PMID:15701641 PMID:21873635 MGI:3579758 NCBI chr16:87,949,216...88,077,318
Ensembl chr16:87,949,244...88,077,318
JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,112,153...92,134,803
JBrowse link
G DEDD death effector domain containing involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5000188|PMID:21135503) Ensembl
MGI
PMID:21135503 GO_REF:0000107 MGI:5000188 NCBI chr 1:161,120,974...161,132,783
Ensembl chr 1:161,120,974...161,132,688
JBrowse link
G DYSF dysferlin acts_upstream_of_or_within ISO (MGI:5433472|PMID:20724702) MGI PMID:20724702 MGI:5433472 NCBI chr 2:71,453,154...71,686,763
Ensembl chr 2:71,453,561...71,686,763
JBrowse link
G EGFR epidermal growth factor receptor involved_in IDA (PMID:17115032) UniProt PMID:17115032 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G FBXO43 F-box protein 43 acts_upstream_of_or_within ISO (MGI:3663227|PMID:16966421) MGI PMID:16966421 MGI:3663227 NCBI chr 8:100,133,351...100,150,569
Ensembl chr 8:100,133,351...100,145,817
JBrowse link
G FLNA filamin A involved_in IMP (PMID:18322202) BHF-UCL PMID:18322202 NCBI chr  X:154,348,531...154,374,634
Ensembl chr  X:154,348,524...154,374,634
JBrowse link
G FMN2 formin 2 involved_in IMP (PMID:23375502) UniProt PMID:23375502 NCBI chr 1:240,091,883...240,475,187
Ensembl chr 1:240,014,348...240,475,187
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3775717|PMID:16841086) Ensembl
MGI
PMID:16841086 GO_REF:0000107 MGI:3775717 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3054180|PMID:15317856) Ensembl
MGI
PMID:15317856 GO_REF:0000107 MGI:3054180 NCBI chr16:9,753,404...10,182,928
Ensembl chr16:9,753,404...10,182,928
JBrowse link
G GRIN2C glutamate ionotropic receptor NMDA type subunit 2C involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3054180|PMID:15317856) Ensembl
MGI
PMID:15317856 GO_REF:0000107 MGI:3054180 NCBI chr17:74,842,021...74,860,843
Ensembl chr17:74,842,023...74,861,504
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 5:75,336,334...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G INS insulin involved_in IDA (PMID:15185208) UniProt PMID:15185208 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in IMP (PMID:17379480), (PMID:18156187) BHF-UCL PMID:17379480 PMID:18156187 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622
JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 involved_in IDA (PMID:11459825) UniProt PMID:11459825 NCBI chr 4:120,055,623...120,066,848
Ensembl chr 4:120,055,623...120,066,858
JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in IDA (PMID:11459826) UniProt PMID:11459826 NCBI chr 1:11,674,480...11,691,559
Ensembl chr 1:11,674,480...11,691,650
JBrowse link
G MDM4 MDM4 regulator of p53 involved_in IMP (PMID:10608892) UniProt PMID:10608892 NCBI chr 1:204,516,377...204,558,120
Ensembl chr 1:204,516,379...204,558,120
JBrowse link
G MYCBP2 MYC binding protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3849342|PMID:19398581) Ensembl
MGI
PMID:19398581 GO_REF:0000107 MGI:3849342 NCBI chr13:77,044,657...77,327,098
Ensembl chr13:77,042,474...77,327,094
JBrowse link
G NOS2 nitric oxide synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NRG1 neuregulin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4454957|PMID:20448149) Ensembl
MGI
PMID:20448149 GO_REF:0000107 MGI:4454957 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in ISO (MGI:5575789|PMID:24899725) ParkinsonsUK-UCL PMID:24899725 MGI:5575789 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PHB prohibitin involved_in IMP (PMID:24732013) UniProt PMID:24732013 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,052...49,414,901
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in IDA (PMID:11533658) ParkinsonsUK-UCL PMID:11533658 NCBI chr19:9,835,318...9,849,689
Ensembl chr19:9,835,257...9,849,689
JBrowse link
G PRKCG protein kinase C gamma involved_in IDA (PMID:15808853) HGNC-UCL PMID:15808853 NCBI chr19:53,882,197...53,907,652
Ensembl chr19:53,879,190...53,907,652
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3581324|PMID:15923614) Ensembl
MGI
PMID:15923614 GO_REF:0000107 MGI:3581324 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G RILP Rab interacting lysosomal protein involved_in IDA (PMID:17010938) UniProt PMID:17010938 NCBI chr17:1,646,150...1,650,077
Ensembl chr17:1,646,145...1,649,866
JBrowse link
G SERPINB12 serpin family B member 12 involved_in NAS (PMID:11604408) UniProt PMID:11604408 NCBI chr18:63,519,164...63,569,329
Ensembl chr18:63,542,369...63,569,329
JBrowse link
G SERPINE2 serpin family E member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3521551|PMID:15509762)
(MGI:3654805|PMID:16319172)
Ensembl
MGI
PMID:15509762 PMID:16319172 GO_REF:0000107 MGI:3521551 MGI:3654805 NCBI chr 2:223,975,045...224,039,286
Ensembl chr 2:223,975,045...224,039,318
JBrowse link
G SF3B3 splicing factor 3b subunit 3 involved_in IDA (PMID:23951410) CACAO PMID:23951410 NCBI chr16:70,523,816...70,577,668
Ensembl chr16:70,523,791...70,577,670
JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within ISO (MGI:3624046|PMID:16611981) MGI PMID:16611981 MGI:3624046 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463
JBrowse link
G SIRT2 sirtuin 2 involved_in IMP (PMID:20543840) UniProt PMID:20543840 NCBI chr19:38,878,555...38,899,733
Ensembl chr19:38,878,555...38,899,862
JBrowse link
G SMAD3 SMAD family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,173
JBrowse link
G SMAD4 SMAD family member 4 involved_in ISO PMID:20097766 BHF-UCL PMID:20097766 RGD:11079190 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045
JBrowse link
G SNX12 sorting nexin 12 involved_in IDA (PMID:22719997) UniProt PMID:22719997 NCBI chr  X:71,059,247...71,073,426
Ensembl chr  X:71,056,332...71,073,426
JBrowse link
G SNX3 sorting nexin 3 involved_in IDA (PMID:18767904) UniProt PMID:18767904 NCBI chr 6:108,211,222...108,261,040
Ensembl chr 6:108,211,222...108,261,246
JBrowse link
G TRIM40 tripartite motif containing 40 involved_in IDA (PMID:21474709) UniProt PMID:21474709 NCBI chr 6:30,135,998...30,148,773
Ensembl chr 6:30,136,124...30,148,735
JBrowse link
negative regulation of cellular protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRAID all-trans retinoic acid induced differentiation factor involved_in IDA (PMID:21723284) UniProt PMID:21723284 NCBI chr 2:27,212,041...27,217,183
Ensembl chr 2:27,212,027...27,217,178
JBrowse link
G CDK2 cyclin dependent kinase 2 involved_in ISO (PMID:15750306) AgBase PMID:15750306 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in IDA (PMID:16173922) UniProt PMID:16173922 NCBI chr17:47,967,904...47,981,781
Ensembl chr17:47,967,810...47,981,781
JBrowse link
G DAB2IP DAB2 interacting protein involved_in IDA (PMID:19903888) UniProt PMID:19903888 NCBI chr 9:121,566,883...121,785,530
Ensembl chr 9:121,567,057...121,785,530
JBrowse link
G NELL1 neural EGFL like 1 involved_in IDA (PMID:21723284) UniProt PMID:21723284 NCBI chr11:20,669,551...21,575,686
Ensembl chr11:20,669,551...21,575,686
JBrowse link
G RGP1 RGP1 homolog, RAB6A GEF complex partner 1 involved_in IMP (PMID:23091056) UniProt PMID:23091056 NCBI chr 9:35,749,287...35,758,585
Ensembl chr 9:35,749,287...35,758,585
JBrowse link
G RIC1 RIC1 homolog, RAB6A GEF complex partner 1 involved_in IMP (PMID:23091056) UniProt PMID:23091056 NCBI chr 9:5,629,030...5,778,633
Ensembl chr 9:5,629,025...5,776,557
JBrowse link
negative regulation of chaperone-mediated autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSA cathepsin A involved_in IGI (PMID:12505983) ParkinsonsUK-UCL PMID:12505983 NCBI chr20:45,890,144...45,898,820
Ensembl chr20:45,890,144...45,898,949
JBrowse link
G SNCA synuclein alpha involved_in IMP (PMID:20697033) ParkinsonsUK-UCL PMID:20697033 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SNRNP70 small nuclear ribonucleoprotein U1 subunit 70 involved_in TAS (PMID:25719862) ParkinsonsUK-UCL PMID:25719862 NCBI chr19:49,085,451...49,108,606
Ensembl chr19:49,085,419...49,108,605
JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CST3 cystatin C involved_in IMP (PMID:10545518) BHF-UCL PMID:10545518 NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473
JBrowse link
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IDA (PMID:23129660) UniProt PMID:23129660 NCBI chr19:2,754,714...2,783,317
Ensembl chr19:2,754,715...2,783,362
JBrowse link
G SVIP small VCP interacting protein involved_in IMP
IBA
(PMID:17872946)
(PMID:21873635)
UniProt
GO_Central
PMID:17872946 PMID:21873635 NCBI chr11:22,812,429...22,829,865
Ensembl chr11:22,813,799...22,830,299
JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IMP (PMID:19135427) ParkinsonsUK-UCL PMID:19135427 NCBI chr18:158,557...214,629
Ensembl chr18:158,383...214,629
JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 involved_in ISS UniProt GO_REF:0000024 NCBI chr11:77,589,953...77,610,356
Ensembl chr11:77,589,391...77,610,356
JBrowse link
G UBXN1 UBX domain protein 1 involved_in IMP (PMID:21135095) ParkinsonsUK-UCL PMID:21135095 NCBI chr11:62,676,500...62,679,116
Ensembl chr11:62,676,498...62,679,117
JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in IMP (PMID:22590560) ParkinsonsUK-UCL PMID:22590560 NCBI chr21:15,729,947...15,880,064
Ensembl chr21:15,729,982...15,880,064
JBrowse link
negative regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 involved_in IDA (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr15:60,347,151...60,398,025
Ensembl chr15:60,347,134...60,402,883
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in IDA (PMID:16912035) HGNC-UCL PMID:16912035 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564
JBrowse link
negative regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP13A2 ATPase cation transporting 13A2 involved_in TAS (PMID:22885599) ParkinsonsUK-UCL PMID:22885599 NCBI chr 1:16,985,958...17,011,972
Ensembl chr 1:16,985,958...17,011,928
JBrowse link
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IMP (PMID:25588945) UniProt PMID:25588945 NCBI chr 8:97,775,788...97,853,013
Ensembl chr 8:97,775,057...97,853,013
JBrowse link
G MGAT3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase acts_upstream_of_or_within ISS UniProt GO_REF:0000024 NCBI chr22:39,457,012...39,492,194
Ensembl chr22:39,457,012...39,492,194
JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chr16:46,656,132...46,689,194
Ensembl chr16:46,656,132...46,689,518
JBrowse link
negative regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 involved_in IDA (PMID:18383040) BHF-UCL PMID:18383040 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G LRIG2 leucine rich repeats and immunoglobulin like domains 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5702499|PMID:26651291) Ensembl
MGI
PMID:26651291 GO_REF:0000107 MGI:5702499 NCBI chr 1:113,073,170...113,132,260
Ensembl chr 1:113,073,198...113,132,260
JBrowse link
G PTPN3 protein tyrosine phosphatase non-receptor type 3 involved_in IMP (PMID:12207026) BHF-UCL PMID:12207026 NCBI chr 9:109,375,694...109,538,395
Ensembl chr 9:109,375,466...109,498,313
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in TAS (PMID:27853422) ARUK-UCL PMID:27853422 NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,946,906...21,111,813
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in IDA
IBA
(PMID:12714508)
(PMID:21873635)
UniProt
GO_Central
PMID:12714508 PMID:21873635 NCBI chr  X:47,582,408...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 involved_in IBA
IMP
(PMID:21873635)
(PMID:18383040)
GO_Central
BHF-UCL
PMID:18383040 PMID:21873635 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041
JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:12,153,068...12,158,912
Ensembl chr 3:12,153,068...12,158,912
JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase involved_in IDA (PMID:8175643) CAFA PMID:8175643 NCBI chr 9:113,386,312...113,401,301
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G F8A1 coagulation factor VIII associated 1 involved_in IMP (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:154,886,355...154,888,061
Ensembl chr  X:154,886,355...154,888,061
JBrowse link
G F8A2 coagulation factor VIII associated 2 involved_in IMP (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:155,382,095...155,383,801
Ensembl chr  X:155,382,095...155,383,801
JBrowse link
G F8A3 coagulation factor VIII associated 3 involved_in IMP (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:155,456,914...155,458,620
Ensembl chr  X:155,456,914...155,458,620
JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 involved_in IMP (PMID:21669198) BHF-UCL PMID:21669198 NCBI chr16:75,566,379...75,577,881
Ensembl chr16:75,566,375...75,577,881
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in ISS (PMID:17517623) ARUK-UCL PMID:17517623 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
JBrowse link
G LAMP3 lysosomal associated membrane protein 3 involved_in IMP (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chr 3:183,122,215...183,162,761
Ensembl chr 3:183,122,215...183,163,839
JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 involved_in IMP (PMID:29295817) UniProt PMID:29295817 NCBI chr 2:159,712,494...159,771,027
Ensembl chr 2:159,712,457...159,771,027
JBrowse link
G OPHN1 oligophrenin 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:68,042,344...68,433,841
Ensembl chr  X:67,949,349...68,433,913
JBrowse link
G PRKCG protein kinase C gamma involved_in ISS UniProt GO_REF:0000024 NCBI chr19:53,882,197...53,907,652
Ensembl chr19:53,879,190...53,907,652
JBrowse link
G PSME3IP1 proteasome activator subunit 3 interacting protein 1 involved_in IMP (PMID:29934401) UniProt PMID:29934401 NCBI chr16:57,152,466...57,186,116
Ensembl chr16:57,152,466...57,186,116
JBrowse link
G PSMF1 proteasome inhibitor subunit 1 involved_in IDA (PMID:10764772) UniProt PMID:10764772 NCBI chr20:1,113,263...1,172,246
Ensembl chr20:1,113,240...1,189,415
JBrowse link
G SCO1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO (MGI:5643882|PMID:25683716) MGI PMID:25683716 MGI:5643882 NCBI chr17:10,672,474...10,697,533
Ensembl chr17:10,672,474...10,698,375
JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:49,108,050...49,120,933
Ensembl chr 3:49,108,046...49,120,938
JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in IDA (PMID:24475098) ParkinsonsUK-UCL PMID:24475098 NCBI chr14:103,556,551...103,562,657
Ensembl chr14:103,556,545...103,562,657
JBrowse link
G BAG6 BAG cochaperone 6 involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:31,639,028...31,660,900
Ensembl chr 6:31,639,028...31,652,705
JBrowse link
G CAMLG calcium modulating ligand involved_in IMP (PMID:20553626) UniProt PMID:20553626 NCBI chr 5:134,738,548...134,752,157
Ensembl chr 5:134,738,495...134,752,157
JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IDA (PMID:23398316) UniProt PMID:23398316 NCBI chr 8:22,604,740...22,621,514
Ensembl chr 8:22,604,632...22,621,514
JBrowse link
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr16:10,944,539...11,193,272
Ensembl chr16:10,944,564...11,182,186
JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IMP (PMID:28263186) UniProt PMID:28263186 NCBI chr20:3,190,350...3,204,682
Ensembl chr20:3,190,350...3,204,685
JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H involved_in IDA (PMID:32269044) FlyBase PMID:32269044 NCBI chr 8:116,642,130...116,755,823
Ensembl chr 8:116,642,130...116,766,925
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in IMP
IBA
(PMID:15313915)
(PMID:21873635)
UniProt
GO_Central
PMID:15313915 PMID:21873635 NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459
JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr19:14,477,761...14,496,133
Ensembl chr19:14,477,760...14,496,149
JBrowse link
G HFE homeostatic iron regulator involved_in IC (PMID:24904118) BHF-UCL PMID:24904118 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in
acts_upstream_of_or_within
IDA
IMP
(PMID:24613385)
(PMID:16280321)
UniProt
MGI
PMID:16280321 PMID:24613385 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
JBrowse link
G KLHL40 kelch like family member 40 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5586592|PMID:24960163)
GO_Central
MGI
PMID:21873635 PMID:24960163 MGI:5586592 NCBI chr 3:42,685,537...42,692,544
Ensembl chr 3:42,685,537...42,692,544
JBrowse link
G MAP1A microtubule associated protein 1A involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr15:43,517,608...43,531,611
Ensembl chr15:43,510,958...43,531,620
JBrowse link
G MTM1 myotubularin 1 acts_upstream_of_or_within ISO (MGI:5510937|PMID:23695157) MGI PMID:23695157 MGI:5510937 NCBI chr  X:150,562,658...150,673,143
Ensembl chr  X:150,568,621...150,673,143
JBrowse link
G N4BP1 NEDD4 binding protein 1 involved_in ISS
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr16:48,538,726...48,610,214
Ensembl chr16:48,538,726...48,620,148
JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IMP (PMID:22522597) UniProt PMID:22522597 NCBI chr19:47,745,546...47,757,058
Ensembl chr19:47,745,546...47,757,058
JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IMP (PMID:26678539) UniProt PMID:26678539 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,104...71,575,892
JBrowse link
G PANO1 proapoptotic nucleolar protein 1 involved_in IMP (PMID:22094112) UniProt PMID:22094112 NCBI chr11:796,633...799,179
Ensembl chr11:797,511...799,185
Ensembl chr11:797,511...799,185
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IDA (PMID:17015834) ParkinsonsUK-UCL PMID:17015834 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PBK PDZ binding kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5293269|PMID:21715333) Ensembl
MGI
PMID:21715333 GO_REF:0000107 MGI:5293269 NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082
JBrowse link
G RPL11 ribosomal protein L11 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:23,691,779...23,696,835
Ensembl chr 1:23,691,742...23,696,835
JBrowse link
G RYBP RING1 and YY1 binding protein involved_in IMP (PMID:27060496) UniProt PMID:27060496 NCBI chr 3:72,374,593...72,446,623
Ensembl chr 3:72,371,825...72,446,623
JBrowse link
G SDCBP syndecan binding protein involved_in IMP (PMID:25893292) UniProt PMID:25893292 NCBI chr 8:58,553,261...58,582,860
Ensembl chr 8:58,552,924...58,582,859
JBrowse link
G SENP1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO (MGI:3818351|PMID:17981124) MGI PMID:17981124 MGI:3818351 NCBI chr12:48,042,893...48,106,308
Ensembl chr12:48,042,897...48,106,079
JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3624046|PMID:16611981) Ensembl
MGI
PMID:16611981 GO_REF:0000107 MGI:3624046 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463
JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5310666|PMID:22285184) Ensembl
MGI
PMID:22285184 GO_REF:0000107 MGI:5310666 NCBI chr 3:47,585,269...47,781,893
Ensembl chr 3:47,585,269...47,782,106
JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in IDA (PMID:11278372) BHF-UCL PMID:11278372 NCBI chr 5:69,364,743...69,369,824
Ensembl chr 5:69,364,743...69,370,013
JBrowse link
G TLK2 tousled like kinase 2 involved_in IMP (PMID:20016786) UniProt PMID:20016786 NCBI chr17:62,470,908...62,615,481
Ensembl chr17:62,458,658...62,615,481
JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IMP
IBA
(PMID:23213251)
(PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:23213251 NCBI chr 6:30,326,469...30,343,729
Ensembl chr 6:30,326,479...30,343,729
JBrowse link
G TTC36 tetratricopeptide repeat domain 36 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:6362140|PMID:31537781) Ensembl
MGI
PMID:31537781 GO_REF:0000107 MGI:6362140 NCBI chr11:118,527,474...118,530,993
Ensembl chr11:118,527,472...118,531,197
JBrowse link
G UBXN1 UBX domain protein 1 involved_in IDA (PMID:20351172) UniProt PMID:20351172 NCBI chr11:62,676,500...62,679,116
Ensembl chr11:62,676,498...62,679,117
JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IMP (PMID:23770237) UniProt PMID:23770237 NCBI chr 1:193,012,254...193,060,140
Ensembl chr 1:193,012,250...193,060,080
JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IMP (PMID:26678539) UniProt PMID:26678539 NCBI chr16:8,892,097...8,963,912
Ensembl chr16:8,892,097...8,975,328
JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in IMP (PMID:22354037) BHF-UCL PMID:22354037 NCBI chr10:28,532,772...28,623,112
Ensembl chr10:28,532,493...28,623,112
JBrowse link
negative regulation of proteolysis involved in cellular protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:25217637)
(MGI:5468878|PMID:23277542)
ParkinsonsUK-UCL
MGI
PMID:23277542 PMID:25217637 MGI:5468878 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G EFNA1 ephrin A1 involved_in IGI (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr 1:155,127,876...155,134,899
Ensembl chr 1:155,127,876...155,134,899
JBrowse link
G EPHA4 EPH receptor A4 involved_in IGI (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr 2:221,418,027...221,574,202
Ensembl chr 2:221,418,027...221,574,202
JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STYX serine/threonine/tyrosine interacting protein involved_in IBA
IMP
(PMID:21873635)
(PMID:28007894)
GO_Central
UniProt
PMID:21873635 PMID:28007894 NCBI chr14:52,730,159...52,774,989
Ensembl chr14:52,730,166...52,774,989
JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (MGI:4461099|PMID:20100865) MGI PMID:20100865 MGI:4461099 NCBI chr 6:34,889,255...35,097,992
Ensembl chr 6:34,889,255...35,091,406
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within
IDA
ISO
(PMID:16173922), (PMID:18560357)
(MGI:5468878|PMID:23277542)
UniProt
MGI
PMID:16173922 PMID:18560357 PMID:23277542 MGI:5468878 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in IGI (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835
JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in IGI (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr16:58,157,907...58,198,106
Ensembl chr16:58,157,907...58,198,106
JBrowse link
G HFE homeostatic iron regulator involved_in IDA (PMID:24904118) BHF-UCL PMID:24904118 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IMP (PMID:21628596) FlyBase PMID:21628596 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998
JBrowse link
G PDCL3 phosducin like 3 acts_upstream_of_or_within IMP (PMID:23792958) MGI PMID:23792958 NCBI chr 2:100,562,993...100,577,472
Ensembl chr 2:100,562,993...100,576,739
JBrowse link
G PML PML nuclear body scaffold involved_in IMP (PMID:15195100) UniProt PMID:15195100 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:73,136,436...73,223,691
Ensembl chr14:73,136,418...73,223,691
JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 1:226,870,594...226,903,829
Ensembl chr 1:226,870,184...226,927,726
JBrowse link
G QRICH2 glutamine rich 2 involved_in IMP (PMID:30683861) UniProt PMID:30683861 NCBI chr17:76,271,296...76,308,811
Ensembl chr17:76,274,049...76,308,276
JBrowse link
G RPL11 ribosomal protein L11 involved_in IMP (PMID:18560357) CAFA PMID:18560357 NCBI chr 1:23,691,779...23,696,835
Ensembl chr 1:23,691,742...23,696,835
JBrowse link
G RPL23 ribosomal protein L23 involved_in IDA (PMID:15314173) CAFA PMID:15314173 NCBI chr17:38,847,860...38,853,721
Ensembl chr17:38,847,860...38,853,764
JBrowse link
G RPL5 ribosomal protein L5 involved_in IDA (PMID:18560357) CAFA PMID:18560357 NCBI chr 1:92,831,986...92,841,924
Ensembl chr 1:92,832,013...92,841,924
JBrowse link
G RPS7 ribosomal protein S7 involved_in IDA (PMID:17310983) CAFA PMID:17310983 NCBI chr 2:3,575,260...3,580,920
Ensembl chr 2:3,575,260...3,580,920
JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IDA (PMID:23129660) UniProt PMID:23129660 NCBI chr19:2,754,714...2,783,317
Ensembl chr19:2,754,715...2,783,362
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4355593|PMID:19684112) Ensembl
MGI
PMID:19684112 GO_REF:0000107 MGI:4355593 NCBI chr10:102,502,801...102,633,535
Ensembl chr10:102,503,972...102,633,535
JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in IMP (PMID:17237821) ParkinsonsUK-UCL PMID:17237821 NCBI chr  X:71,366,220...71,530,525
Ensembl chr  X:71,366,222...71,532,374
JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IDA (PMID:19100260) BHF-UCL PMID:19100260 NCBI chr 6:30,326,469...30,343,729
Ensembl chr 6:30,326,479...30,343,729
JBrowse link
G WNT1 Wnt family member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3628833|PMID:16601693) Ensembl
MGI
PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr12:48,978,322...48,982,620
Ensembl chr12:48,978,322...48,982,620
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18539
    metabolic process 11872
      catabolic process 2683
        negative regulation of catabolic process 352
          negative regulation of protein catabolic process 134
            negative regulation of cellular protein catabolic process + 84
            negative regulation of chaperone-mediated autophagy 3
            negative regulation of elastin catabolic process 1
            negative regulation of membrane protein ectodomain proteolysis 8
Path 2
Term Annotations click to browse term
  biological_process 18539
    metabolic process 11872
      organic substance metabolic process 11379
        macromolecule metabolic process 9825
          macromolecule catabolic process 1407
            protein catabolic process 1029
              regulation of protein catabolic process 428
                negative regulation of protein catabolic process 134
                  negative regulation of cellular protein catabolic process + 84
                  negative regulation of chaperone-mediated autophagy 3
                  negative regulation of elastin catabolic process 1
                  negative regulation of membrane protein ectodomain proteolysis 8
paths to the root