Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:SH2 domain binding
go back to main search page
Accession:GO:0042169 term browser browse the term
Definition:Binding to a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class.


show annotations for term's descendants           Sort by:
SH2 domain binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase enables ISO UniProtKB:P46108 (PMID:12384576) RGD PMID:12384576 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Afap1 actin filament associated protein 1 enables IPI
IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central
RGD		 PMID:12114187 GO_REF:0000033 GO_REF:0000118, RGD:625602 NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263 		JBrowse link
G Afap1l2 actin filament associated protein 1-like 2 enables ISO
IBA		 UniProtKB:P12931 (PMID:17412687)
GO_REF:0000033		 RGD
GO_Central		 PMID:17412687 GO_REF:0000033 NCBI chr 1:255,964,238...256,060,828
Ensembl chr 1:255,964,238...256,060,820 		JBrowse link
G Arhgap5 Rho GTPase activating protein 5 enables ISO UniProtKB:P20936 (PMID:1689011) RGD PMID:1689011 NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660 		JBrowse link
G Blnk B-cell linker enables ISO (PMID:9697839) RGD PMID:9697839 NCBI chr 1:239,753,640...239,821,113
Ensembl chr 1:239,753,648...239,821,113 		JBrowse link
G Ccdc88a coiled coil domain containing 88A enables ISO UniProtKB:P27986 (PMID:21954290) RGD PMID:21954290 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein enables ISO UniProtKB:P56945 (PMID:9472046) RGD PMID:9472046 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component enables ISO (PMID:8636124) RGD PMID:8636124 NCBI chr 1:165,137,277...165,167,303
Ensembl chr 1:165,137,215...165,167,303 		JBrowse link
G Dag1 dystroglycan 1 enables ISO (PMID:11724572) RGD PMID:11724572 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein enables ISO
IEA		 UniProtKB:Q63HR2|UniProtKB:Q68CZ2|UniProtKB:Q8IZW8|UniProtKB:Q9HBL0 (PMID:17190795)
GO_REF:0000107		 RGD
Ensembl		 PMID:17190795 GO_REF:0000107 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 enables ISO PR:P47941|PR:Q64010 (PMID:19307307) RGD PMID:19307307 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Ghr growth hormone receptor IDA
IPI
IMP		 RGD PMID:12586763 PMID:10976913 PMID:10976913 RGD:728498, RGD:1624964, RGD:1624964 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 enables ISO
IEA		 UniProtKB:P22681 (PMID:5668240)
GO_REF:0000107		 RGD
Ensembl		 PMID:5668240 GO_REF:0000107 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500 		JBrowse link
G Irs1 insulin receptor substrate 1 enables IPI PMID:8491186 UniProt PMID:8491186 RGD:8553343 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Jak2 Janus kinase 2 enables ISO UniProtKB:O15524 (PMID:9727029) RGD PMID:9727029 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 enables ISO (PMID:9045636) RGD PMID:9045636 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180 		JBrowse link
G Khdrbs2 KH RNA binding domain containing, signal transduction associated 2 enables ISO (PMID:10077576) RGD PMID:10077576 NCBI chr 9:34,447,023...34,953,684
Ensembl chr 9:34,447,056...34,915,530 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase enables ISO UniProtKB:O09039 (MGI:3041996|PMID:14612394) RGD PMID:14612394 MGI:3041996 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Lat2 linker for activation of T cells family, member 2 enables ISO UniProtKB:Q9ULZ2 (PMID:14722116), (PMID:20442417) RGD PMID:14722116 PMID:20442417 NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288 		JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 enables ISO (PMID:12359715) RGD PMID:12359715 NCBI chr13:45,134,825...45,145,381
Ensembl chr13:45,134,834...45,145,381 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase enables ISO
IEA		 UniProtKB:P03406|UniProtKB:Q78524 (PMID:7852312), (PMID:8794306)
GO_REF:0000107		 RGD
Ensembl		 PMID:7852312 PMID:8794306 GO_REF:0000107 NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 IDA RGD PMID:8910399 RGD:1599952 NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310 		JBrowse link
G Nlk nemo like kinase enables ISO UniProtKB:P42227 (MGI:3843436|PMID:15004007) RGD PMID:15004007 MGI:3843436 NCBI chr10:63,467,388...63,590,960
Ensembl chr10:63,438,222...63,589,730 		JBrowse link
G Nup62 nucleoporin 62 enables ISO
ISS		 (PMID:8650207)
GO_REF:0000024		 RGD
UniProt		 PMID:8650207 GO_REF:0000024 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 enables ISO
IEA
IBA		 (PMID:10790433)
GO_REF:0000118
GO_REF:0000033		 RGD
TreeGrafter
GO_Central		 PMID:10790433 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849 		JBrowse link
G Ptk2 protein tyrosine kinase 2 enables ISO UniProtKB:P20936 (PMID:15077193) RGD PMID:15077193 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 enables IEA
ISO		 GO_REF:0000107
(PMID:8632004)		 Ensembl
RGD		 PMID:8632004 GO_REF:0000107 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Rack1 receptor for activated C kinase 1 enables ISS
ISO		 GO_REF:0000024
(PMID:11279199), (PMID:9584165)		 UniProt
RGD		 PMID:9584165 PMID:11279199 GO_REF:0000024 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rufy1 RUN and FYVE domain containing 1 enables ISO UniProtKB:P29320 (PMID:11877430) RGD PMID:11877430 NCBI chr10:34,705,741...34,750,644
Ensembl chr10:34,705,741...34,750,644 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 enables ISO (PMID:9233773) RGD PMID:9233773 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Sh3pxd2b SH3 and PX domains 2B enables ISO (MGI:3826299|PMID:18959745) RGD PMID:18959745 MGI:3826299 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170 		JBrowse link
G Shcbp1 SHC binding and spindle associated 1 enables ISO (PMID:10086341) RGD PMID:10086341 NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844 		JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 enables ISO (PMID:12163025) RGD PMID:12163025 NCBI chr 1:93,817,301...93,826,376
Ensembl chr 1:93,817,335...93,825,931 		JBrowse link
G Skap1 src kinase associated phosphoprotein 1 enables IPI
ISO
IEA		 (PMID:9195899)
GO_REF:0000107		 RGD
Ensembl		 PMID:9195899 PMID:12681493 GO_REF:0000107, RGD:1299442 NCBI chr10:81,425,472...81,732,651
Ensembl chr10:81,425,525...81,732,650 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 enables ISO (PMID:9774102) RGD PMID:9774102 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Snap91 synaptosome associated protein 91 IPI RGD PMID:11779129 RGD:70605 NCBI chr 8:87,738,056...87,852,690
Ensembl chr 8:87,738,824...87,852,367 		JBrowse link
G Sqstm1 sequestosome 1 enables ISO
ISS		 (PMID:8650207)
GO_REF:0000024		 RGD
UniProt		 PMID:8650207 GO_REF:0000024 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase enables ISO UniProtKB:P56945 (PMID:8070403) RGD PMID:8070403 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Syk spleen associated tyrosine kinase enables IEA
ISO		 GO_REF:0000107
(PMID:27609517)		 Ensembl
RGD		 PMID:27609517 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Syngr3 synaptogyrin 3 enables ISO (PMID:18706977) RGD PMID:18706977 NCBI chr10:13,710,553...13,715,309
Ensembl chr10:13,704,998...13,715,669 		JBrowse link
G Syp synaptophysin enables IEA
ISO		 GO_REF:0000107
(PMID:18706977)		 Ensembl
RGD		 PMID:18706977 GO_REF:0000107 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 enables ISO UniProtKB:P39688 (MGI:2653708|PMID:12538589) RGD PMID:12538589 MGI:2653708 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    binding 17950
      protein binding 14727
        protein domain specific binding 818
          SH2 domain binding 42
paths to the root