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ONTOLOGY REPORT - ANNOTATIONS


Term:neurotransmitter catabolic process
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Accession:GO:0042135 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
Synonyms:exact_synonym: neurotransmitter breakdown;   neurotransmitter catabolism;   neurotransmitter degradation


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neurotransmitter catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:631980
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 JBrowse link 17 42,133,076 42,159,413 RGD:1624291
G Colq collagen like tail subunit of asymmetric acetylcholinesterase JBrowse link 16 7,626,380 7,681,621 RGD:1600115
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:1600115
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing JBrowse link 1 166,985,468 166,989,681 RGD:1600115
G Maoa monoamine oxidase A JBrowse link X 6,554,698 6,620,722 RGD:1600115
G Maob monoamine oxidase B JBrowse link X 6,430,694 6,533,520 RGD:633242
RGD:2316732
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 JBrowse link 8 17,453,198 17,525,906 RGD:1624291
G Prima1 proline rich membrane anchor 1 JBrowse link 6 127,075,954 127,127,985 RGD:1600115
acetylcholine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:1580870
RGD:1600115
RGD:1624291
RGD:2301213
RGD:2301207
RGD:2301205
RGD:2301204
RGD:2301203
RGD:2301199
RGD:2301197
RGD:2301195
RGD:2301187
acetylcholine catabolic process in synaptic cleft term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:12050110
beta-alanine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 JBrowse link 6 108,146,552 108,167,185 RGD:1599052
choline catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmgdh dimethylglycine dehydrogenase JBrowse link 2 23,289,376 23,370,360 RGD:632576
RGD:1624291
RGD:1600115
G Sardh sarcosine dehydrogenase JBrowse link 3 5,737,203 5,802,153 RGD:634034
gamma-aminobutyric acid catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:631980
RGD:1624291
RGD:13792537
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 JBrowse link 17 42,133,076 42,159,413 RGD:1600115
RGD:1624291
RGD:632258
glycine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gldc glycine decarboxylase JBrowse link 1 248,295,140 248,377,122 RGD:1624291
glycine decarboxylation via glycine cleavage system term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07007134.1 RGD:1600115
G AABR07067762.1 RGD:1600115
G Amt aminomethyltransferase JBrowse link 8 117,068,388 117,078,633 RGD:1624291
RGD:13792537
G Gcsh glycine cleavage system protein H JBrowse link 19 49,522,054 49,532,811 RGD:1598699
G Gldc glycine decarboxylase JBrowse link 1 248,295,140 248,377,122 RGD:1642728
RGD:13792537
histamine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hnmt histamine N-methyltransferase JBrowse link 3 905,111 937,038 RGD:1624291
RGD:1600115
nitric oxide catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:2316786

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    cellular process 18361
      cellular metabolic process 10737
        neurotransmitter metabolic process 159
          neurotransmitter catabolic process 20
            acetylcholine catabolic process + 1
            beta-alanine catabolic process + 1
            choline catabolic process 2
            gamma-aminobutyric acid catabolic process + 2
            glycine catabolic process + 5
            histamine catabolic process 1
            nitric oxide catabolic process 1
            octopamine catabolic process 0
            serotonin catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 19576
    biological regulation 13536
      regulation of biological quality 4289
        regulation of neurotransmitter levels 413
          neurotransmitter metabolic process 159
            neurotransmitter catabolic process 20
              acetylcholine catabolic process + 1
              beta-alanine catabolic process + 1
              choline catabolic process 2
              gamma-aminobutyric acid catabolic process + 2
              glycine catabolic process + 5
              histamine catabolic process 1
              nitric oxide catabolic process 1
              octopamine catabolic process 0
              serotonin catabolic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.