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ONTOLOGY REPORT - ANNOTATIONS

Term:neurotransmitter catabolic process
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Accession:GO:0042135 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
Synonyms:exact_synonym: neurotransmitter breakdown;   neurotransmitter catabolism;   neurotransmitter degradation


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neurotransmitter catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase involved_in IC PMID:10447691 UniProt PMID:10447691 RGD:631980 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 acts_upstream_of_or_within ISO MGI:2180159 (MGI:3050939|PMID:15262267) RGD PMID:15262267 MGI:3050939 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107 		JBrowse link
G Comt catechol-O-methyltransferase involved_in IEA
ISO		 GO_REF:0000043
GO_REF:0000104
(MGI:4834979|PMID:20626558)		 UniProt
RGD		 PMID:20626558 GO_REF:0000043 GO_REF:0000104 MGI:4834979 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704 		JBrowse link
G Maoa monoamine oxidase A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Maob monoamine oxidase B TAS
IDA		 RGD PMID:12379239 PMID:18539264 RGD:633242, RGD:2316732 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 acts_upstream_of_or_within ISO (MGI:3043497|PMID:15086519), (MGI:5306875|PMID:21908619) RGD PMID:15086519 PMID:21908619 MGI:3043497 MGI:5306875 NCBI chr 8:15,406,119...15,479,714
Ensembl chr 8:15,407,043...15,479,714 		JBrowse link
G Prima1 proline rich membrane anchor 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921 		JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in
acts_upstream_of_or_within		 IDA
IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(MGI:3654414|PMID:16434405), (MGI:65815|PMID:7512968)
(PMID:1517212)		 Ensembl
RGD		 PMID:1517212 PMID:7512968 PMID:16434405 PMID:16052514 PMID:21873635 More... GO_REF:0000107 MGI:3654414 MGI:65815, RGD:1580870, RGD:13792537, RGD:2301213, RGD:2301207, RGD:2301205, RGD:2301204, RGD:2301203, RGD:2301199, RGD:2301197, RGD:2301195, RGD:2301187 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bche butyrylcholinesterase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
acetylcholine catabolic process in synaptic cleft term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in IC PMID:26820598 SynGO PMID:26820598 RGD:12050110 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
histamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase involved_in ISO
ISS		 (PMID:26206890)
GO_REF:0000024		 RGD
UniProt		 PMID:26206890 GO_REF:0000024 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    cellular process 18161
      cellular metabolic process 9535
        neurotransmitter metabolic process 30
          neurotransmitter catabolic process 12
            acetylcholine catabolic process + 2
            histamine catabolic process 1
            octopamine catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 19748
    biological regulation 13456
      regulation of biological quality 3339
        regulation of neurotransmitter levels 260
          neurotransmitter metabolic process 30
            neurotransmitter catabolic process 12
              acetylcholine catabolic process + 2
              histamine catabolic process 1
              octopamine catabolic process 0
paths to the root