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ONTOLOGY REPORT - ANNOTATIONS

Term:neurotransmitter metabolic process
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Accession:GO:0042133 term browser browse the term
Definition:The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
Synonyms:exact_synonym: neurotransmitter metabolism
 never_in_taxon: NCBITaxon:4895 ! Schizosaccharomyces


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neurotransmitter metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtpbp1 ATP/GTP binding carboxypeptidase 1 acts_upstream_of_or_within ISO MGI:1856535 (MGI:62875|PMID:8100981) RGD PMID:8100981 MGI:62875 NCBI chr17:5,120,540...5,238,874
Ensembl chr17:5,120,609...5,238,869 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within ISO MGI:1933976 (MGI:3616353|PMID:16239221) RGD PMID:16239221 MGI:3616353 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 involved_in TAS PMID:8864115 PINC PMID:8864115 RGD:633683 NCBI chr12:41,312,367...41,314,742
Ensembl chr12:41,312,367...41,314,741 		JBrowse link
G Glul glutamate-ammonia ligase TAS RGD PMID:1674354 RGD:632694 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chat choline O-acetyltransferase involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:126256 PMID:21873635 PMID:4008917 PMID:6854006 PMID:334962 RGD:2301195, RGD:13792537, RGD:2301203, RGD:2301199, RGD:2301197 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Slc44a4 solute carrier family 44, member 4 involved_in ISO
ISS		 (PMID:23651124), (PMID:28013291)
GO_REF:0000024		 RGD
UniProt		 PMID:23651124 PMID:28013291 GO_REF:0000024 NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 involved_in
acts_upstream_of_or_within		 IEA
ISO
IMP
IBA		 GO_REF:0000107
MGI:3045463 (MGI:3044863|PMID:15173594)
PMID:10649566
(PMID:11068039)
PMID:21873635		 Ensembl
RGD		 PMID:11068039 PMID:15173594 PMID:10649566 PMID:21873635 GO_REF:0000107 MGI:3044863, RGD:68853, RGD:13792537 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258 		JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in
acts_upstream_of_or_within		 IDA
IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(MGI:3654414|PMID:16434405), (MGI:65815|PMID:7512968)
(PMID:1517212)		 Ensembl
RGD		 PMID:1517212 PMID:7512968 PMID:16434405 PMID:16052514 PMID:21873635 More... GO_REF:0000107 MGI:3654414 MGI:65815, RGD:1580870, RGD:13792537, RGD:2301213, RGD:2301207, RGD:2301205, RGD:2301204, RGD:2301203, RGD:2301199, RGD:2301197, RGD:2301195, RGD:2301187 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bche butyrylcholinesterase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
acetylcholine catabolic process in synaptic cleft term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in IC PMID:26820598 SynGO PMID:26820598 RGD:12050110 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase IMP RGD PMID:16628397 RGD:1580871 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
histamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase involved_in ISO
ISS		 (PMID:26206890)
GO_REF:0000024		 RGD
UniProt		 PMID:26206890 GO_REF:0000024 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012 		JBrowse link
neurotransmitter biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 involved_in ISO (PMID:2925663) RGD PMID:2925663 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568 		JBrowse link
G Chat choline O-acetyltransferase TAS RGD PMID:15477102 RGD:1358491 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Dagla diacylglycerol lipase, alpha acts_upstream_of_or_within
involved_in		 ISS
ISO		 GO_REF:0000024
MGI:4438719 (MGI:4437165|PMID:20147530)
(PMID:14610053)		 UniProt
RGD		 PMID:14610053 PMID:20147530 GO_REF:0000024 MGI:4437165 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232 		JBrowse link
G Daglb diacylglycerol lipase, beta involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
MGI:3529581 (MGI:4437165|PMID:20147530)		 Ensembl
RGD		 PMID:20147530 PMID:21873635 GO_REF:0000107 MGI:4437165, RGD:13792537 NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154 		JBrowse link
G Gad1 glutamate decarboxylase 1 involved_in IDA
ISO		 PMID:1924335
(PMID:17384644), (PMID:8336154)
(MGI:892697|PMID:9177246)		 RGD PMID:8336154 PMID:9177246 PMID:17384644 PMID:1924335 MGI:892697, RGD:728511 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 involved_in IDA
IMP		 PMID:8336154 SynGO PMID:8336154 PMID:8336154 RGD:155230743, RGD:155230743 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Th tyrosine hydroxylase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
neurotransmitter catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase involved_in IC PMID:10447691 UniProt PMID:10447691 RGD:631980 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 acts_upstream_of_or_within ISO MGI:2180159 (MGI:3050939|PMID:15262267) RGD PMID:15262267 MGI:3050939 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107 		JBrowse link
G Comt catechol-O-methyltransferase involved_in IEA
ISO		 GO_REF:0000043
GO_REF:0000104
(MGI:4834979|PMID:20626558)		 UniProt
RGD		 PMID:20626558 GO_REF:0000043 GO_REF:0000104 MGI:4834979 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704 		JBrowse link
G Maoa monoamine oxidase A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Maob monoamine oxidase B TAS
IDA		 RGD PMID:12379239 PMID:18539264 RGD:633242, RGD:2316732 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 acts_upstream_of_or_within ISO (MGI:3043497|PMID:15086519), (MGI:5306875|PMID:21908619) RGD PMID:15086519 PMID:21908619 MGI:3043497 MGI:5306875 NCBI chr 8:15,406,119...15,479,714
Ensembl chr 8:15,407,043...15,479,714 		JBrowse link
G Prima1 proline rich membrane anchor 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921 		JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
octopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase IMP RGD PMID:11521740 RGD:1625401 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 IDA RGD PMID:8888012 RGD:2302806 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862 		JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO MGI:88392 (MGI:3628883|PMID:12204217) RGD PMID:12204217 MGI:3628883 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    metabolic process 12047
      cellular metabolic process 9535
        neurotransmitter metabolic process 30
          acetylcholine metabolic process + 7
          neurotransmitter biosynthetic process + 12
          neurotransmitter catabolic process + 12
          octopamine metabolic process + 3
          phenylethylamine metabolic process involved in synaptic transmission + 0
Path 2
Term Annotations click to browse term
  biological_process 19748
    biological regulation 13456
      regulation of biological quality 3339
        regulation of neurotransmitter levels 260
          neurotransmitter metabolic process 30
            acetylcholine metabolic process + 7
            neurotransmitter biosynthetic process + 12
            neurotransmitter catabolic process + 12
            octopamine metabolic process + 3
            phenylethylamine metabolic process involved in synaptic transmission + 0
paths to the root