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ONTOLOGY REPORT - ANNOTATIONS

Term:neurotransmitter metabolic process
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Accession:GO:0042133 term browser browse the term
Definition:The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
Synonyms:exact_synonym: neurotransmitter metabolism
 never_in_taxon: NCBITaxon:4895 ! Schizosaccharomyces


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neurotransmitter metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtpbp1 ATP/GTP binding protein 1 acts_upstream_of_or_within IMP (MGI:62875|PMID:8100981) MGI PMID:8100981 MGI:62875 NCBI chr13:59,597,348...59,705,184
Ensembl chr13:59,593,556...59,733,041 		JBrowse link
G Cln3 ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) acts_upstream_of_or_within IMP (MGI:3616353|PMID:16239221) MGI PMID:16239221 MGI:3616353 NCBI chr 7:126,170,379...126,184,989
Ensembl chr 7:126,170,379...126,184,989 		JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chat choline acetyltransferase involved_in IBA
ISO		 (MGI:6201960|PMID:21873635) GO_Central
MGI
RGD		 PMID:126256 PMID:334962 PMID:4008917 PMID:6854006 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:2301195 RGD:2301197 RGD:2301199 RGD:2301203 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946 		JBrowse link
G Slc44a4 solute carrier family 44, member 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:35,133,200...35,149,412
Ensembl chr17:35,133,442...35,149,412 		JBrowse link
G Slc5a7 solute carrier family 5 (choline transporter), member 7 acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA		 (MGI:3044863|PMID:15173594)
(MGI:6201960|PMID:21873635)		 MGI
GO_Central		 PMID:15173594 PMID:21873635 GO_REF:0000096 MGI:3044863 MGI:4417868 MGI:4834177 MGI:6201960 NCBI chr17:54,580,618...54,606,071
Ensembl chr17:54,580,618...54,606,062 		JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in
acts_upstream_of_or_within		 ISO
IBA
IDA		 (MGI:6201960|PMID:21873635)
(MGI:3654414|PMID:16434405), (MGI:65815|PMID:7512968)		 MGI
GO_Central
RGD		 PMID:126256 PMID:334962 PMID:1133098 PMID:2731551 PMID:3655326 More... GO_REF:0000096 MGI:3654414 MGI:4417868 MGI:4834177 MGI:6201960 MGI:65815 RGD:1580870 RGD:2301187 RGD:2301195 RGD:2301197 RGD:2301199 RGD:2301203 RGD:2301204 RGD:2301205 RGD:2301207 RGD:2301213 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Bche butyrylcholinesterase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in ISO RGD
MGI		 PMID:16628397 GO_REF:0000096 MGI:4417868 RGD:1580871 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
histamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:23,892,923...23,939,756
Ensembl chr 2:23,892,922...23,939,406 		JBrowse link
neurotransmitter biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh9a1 aldehyde dehydrogenase 9, subfamily A1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:167,177,532...167,196,099
Ensembl chr 1:167,177,560...167,196,101 		JBrowse link
G Chat choline acetyltransferase acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946 		JBrowse link
G Dagla diacylglycerol lipase, alpha involved_in
acts_upstream_of_or_within		 ISO
IMP		 (MGI:4437165|PMID:20147530) MGI PMID:20147530 GO_REF:0000096 MGI:4437165 MGI:4834177 NCBI chr19:10,222,629...10,282,323
Ensembl chr19:10,222,629...10,282,241 		JBrowse link
G Daglb diacylglycerol lipase, beta acts_upstream_of_or_within
involved_in		 IMP
IBA		 (MGI:4437165|PMID:20147530)
(MGI:6201960|PMID:21873635)		 MGI
GO_Central		 PMID:20147530 PMID:21873635 MGI:4437165 MGI:6201960 NCBI chr 5:143,450,239...143,490,197
Ensembl chr 5:143,450,339...143,491,697 		JBrowse link
G Gad1 glutamate decarboxylase 1 involved_in IMP
ISO		 (MGI:892697|PMID:9177246) UniProt
MGI		 PMID:9177246 GO_REF:0000096 MGI:4417868 MGI:4834177 MGI:892697 NCBI chr 2:70,391,644...70,432,358
Ensembl chr 2:70,383,416...70,432,358 		JBrowse link
G Gad2 glutamic acid decarboxylase 2 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 2:22,512,262...22,583,889
Ensembl chr 2:22,512,217...22,583,886 		JBrowse link
G Slc5a7 solute carrier family 5 (choline transporter), member 7 acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr17:54,580,618...54,606,071
Ensembl chr17:54,580,618...54,606,062 		JBrowse link
G Th tyrosine hydroxylase acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865 		JBrowse link
neurotransmitter catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr16:8,331,293...8,439,432
Ensembl chr16:8,331,293...8,439,432 		JBrowse link
G Ache acetylcholinesterase acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Aldh5a1 aldhehyde dehydrogenase family 5, subfamily A1 acts_upstream_of_or_within IMP (MGI:3050939|PMID:15262267) MGI PMID:15262267 MGI:3050939 NCBI chr13:25,091,562...25,121,740
Ensembl chr13:25,091,562...25,121,644 		JBrowse link
G Colq collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr14:31,245,039...31,299,820
Ensembl chr14:31,245,039...31,313,300 		JBrowse link
G Comt catechol-O-methyltransferase involved_in IDA
IMP		 (MGI:4834979|PMID:20626558) SynGO PMID:20626558 MGI:4834979 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602 		JBrowse link
G Maoa monoamine oxidase A acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr  X:16,485,937...16,554,051
Ensembl chr  X:16,485,937...16,554,057 		JBrowse link
G Maob monoamine oxidase B involved_in ISO RGD
MGI		 PMID:18539264 GO_REF:0000096 MGI:4417868 RGD:2316732 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605 		JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 acts_upstream_of_or_within IDA (MGI:3043497|PMID:15086519), (MGI:5306875|PMID:21908619) MGI PMID:15086519 PMID:21908619 MGI:3043497 MGI:5306875 NCBI chr 9:18,233,247...18,308,834
Ensembl chr 9:18,233,247...18,314,291 		JBrowse link
G Prima1 proline rich membrane anchor 1 acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr12:103,160,712...103,208,967
Ensembl chr12:103,163,167...103,208,409 		JBrowse link
G Tomt transmembrane O-methyltransferase acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 7:101,549,010...101,555,572
Ensembl chr 7:101,547,577...101,555,566 		JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta hydroxylase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr10:24,099,415...24,178,681
Ensembl chr10:24,099,415...24,178,688 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 6:40,855,728...40,864,428
Ensembl chr 6:40,855,728...40,864,428 		JBrowse link
octopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta hydroxylase involved_in ISO RGD
MGI		 PMID:11521740 GO_REF:0000096 MGI:4417868 RGD:1625401 NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212 		JBrowse link
positive regulation of acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 involved_in IC (MGI:4437154|PMID:20164328) ARUK-UCL PMID:20164328 MGI:4437154 NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317 		JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 involved_in ISO RGD
MGI		 PMID:8888012 GO_REF:0000096 MGI:4417868 RGD:2302806 NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690 		JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within IGI (MGI:3628883|PMID:12204217) MGI PMID:12204217 MGI:3628883 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28449
    metabolic process 11385
      cellular metabolic process 8830
        neurotransmitter metabolic process 29
          acetylcholine metabolic process + 8
          neurotransmitter biosynthetic process + 13
          neurotransmitter catabolic process + 12
          octopamine metabolic process + 3
          phenylethylamine metabolic process involved in synaptic transmission + 0
Path 2
Term Annotations click to browse term
  biological_process 28449
    biological regulation 13195
      regulation of biological quality 3396
        regulation of neurotransmitter levels 246
          neurotransmitter metabolic process 29
            acetylcholine metabolic process + 8
            neurotransmitter biosynthetic process + 13
            neurotransmitter catabolic process + 12
            octopamine metabolic process + 3
            phenylethylamine metabolic process involved in synaptic transmission + 0
paths to the root