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ONTOLOGY REPORT - ANNOTATIONS


Term:neurotransmitter metabolic process
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Accession:GO:0042133 term browser browse the term
Definition:The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
Synonyms:exact_synonym: neurotransmitter metabolism
 never_in_taxon: NCBITaxon:4895 ! Schizosaccharomyces



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neurotransmitter metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within ISO (MGI:3616353|PMID:16239221) MGI PMID:16239221 MGI:3616353
acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHAT choline O-acetyltransferase ISO RGD PMID:126256 PMID:334962 PMID:4008917 PMID:6854006 RGD:2301195 RGD:2301197 RGD:2301199 RGD:2301203 NCBI chr10:44,574,925...44,629,618 JBrowse link
G SLC44A4 solute carrier family 44 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,526,660...31,542,165
Ensembl chr 6:32,413,441...32,428,550
JBrowse link
G SLC5A7 solute carrier family 5 member 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3044863|PMID:15173594) MGI
Ensembl
PMID:15173594 GO_REF:0000107 MGI:3044863 NCBI chr2A:93,917,086...93,944,308
Ensembl chr2A:109,017,805...109,046,860
JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:3654414|PMID:16434405), (MGI:65815|PMID:7512968) RGD
Ensembl
MGI
PMID:126256 PMID:334962 PMID:1133098 PMID:2731551 PMID:3655326 More... GO_REF:0000107 MGI:3654414 MGI:65815 RGD:1580870 RGD:2301187 RGD:2301195 RGD:2301197 RGD:2301199 RGD:2301203 RGD:2301204 RGD:2301205 RGD:2301207 RGD:2301213 NCBI chr 7:92,915,065...92,922,079
Ensembl chr 7:106,311,944...106,318,184
JBrowse link
acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) ISO RGD PMID:16628397 RGD:1580871 NCBI chr 7:92,915,065...92,922,079
Ensembl chr 7:106,311,944...106,318,184
JBrowse link
histamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNMT histamine N-methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:21,840,342...21,892,744
Ensembl chr2B:142,036,321...142,088,315
JBrowse link
neurotransmitter biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH9A1 aldehyde dehydrogenase 9 family member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:141,094,261...141,130,613
Ensembl chr 1:144,883,839...144,919,670
JBrowse link
G DAGLA diacylglycerol lipase alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4437165|PMID:20147530) MGI
Ensembl
PMID:20147530 GO_REF:0000107 MGI:4437165 NCBI chr11:56,979,558...57,046,589
Ensembl chr11:60,378,493...60,407,095
JBrowse link
G DAGLB diacylglycerol lipase beta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4437165|PMID:20147530) MGI
Ensembl
PMID:20147530 GO_REF:0000107 MGI:4437165 NCBI chr 7:6,995,425...7,034,279
Ensembl chr 7:6,605,250...6,634,169
JBrowse link
G GAD1 glutamate decarboxylase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:58,100,623...58,145,045
Ensembl chr2B:175,558,538...175,602,944
JBrowse link
G GAD2 glutamate decarboxylase 2 involved_in ISO PMID:8336154 SynGO PMID:8336154 RGD:155230743 NCBI chr10:26,392,877...26,481,859
Ensembl chr10:26,759,243...26,843,197
JBrowse link
G TH tyrosine hydroxylase involved_in IEA UniProt GO_REF:0000043 NCBI chr11:2,204,820...2,212,750
Ensembl chr11:2,231,248...2,242,433
JBrowse link
neurotransmitter catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase involved_in IEA UniProt GO_REF:0000043 NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420
JBrowse link
G ALDH5A1 aldehyde dehydrogenase 5 family member A1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3050939|PMID:15262267) MGI
Ensembl
PMID:15262267 GO_REF:0000107 MGI:3050939 NCBI chr 6:24,332,093...24,370,764
Ensembl chr 6:24,665,026...24,705,151
JBrowse link
G COMT catechol-O-methyltransferase involved_in IEA UniProt
Ensembl
InterPro
GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr22:2,704,015...2,731,326
Ensembl chr22:18,375,434...18,402,387
JBrowse link
G MAOB monoamine oxidase B ISO RGD PMID:18539264 RGD:2316732 NCBI chr  X:36,217,710...36,333,516
Ensembl chr  X:44,042,000...44,157,941
JBrowse link
G NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 acts_upstream_of_or_within ISO (MGI:3043497|PMID:15086519), (MGI:5306875|PMID:21908619) MGI PMID:15086519 PMID:21908619 MGI:3043497 MGI:5306875 NCBI chr11:85,105,296...85,163,280
Ensembl chr11:88,600,918...88,658,985
JBrowse link
octopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBH dopamine beta-hydroxylase ISO RGD PMID:11521740 RGD:1625401 NCBI chr 9:104,761,504...104,784,445
Ensembl chr 9:133,371,821...133,393,697
JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PEBP1 phosphatidylethanolamine binding protein 1 ISO RGD PMID:8888012 RGD:2302806 NCBI chr12:115,716,953...115,726,412
Ensembl chr12:119,093,952...119,105,054
JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHR follicle stimulating hormone receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3628883|PMID:12204217) MGI
Ensembl
PMID:12204217 GO_REF:0000107 MGI:3628883 NCBI chr2A:49,088,450...49,287,688
Ensembl chr2A:50,008,328...50,207,258
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15348
    metabolic process 9986
      cellular metabolic process 7792
        neurotransmitter metabolic process 20
          acetylcholine metabolic process + 6
          neurotransmitter biosynthetic process + 9
          neurotransmitter catabolic process + 7
          octopamine metabolic process + 1
          phenylethylamine metabolic process involved in synaptic transmission + 0
Path 2
Term Annotations click to browse term
  biological_process 15348
    biological regulation 10759
      regulation of biological quality 2848
        regulation of neurotransmitter levels 217
          neurotransmitter metabolic process 20
            acetylcholine metabolic process + 6
            neurotransmitter biosynthetic process + 9
            neurotransmitter catabolic process + 7
            octopamine metabolic process + 1
            phenylethylamine metabolic process involved in synaptic transmission + 0
paths to the root