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ONTOLOGY REPORT - ANNOTATIONS


Term:neurotransmitter metabolic process
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Accession:GO:0042133 term browser browse the term
Definition:The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
Synonyms:exact_synonym: neurotransmitter metabolism


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neurotransmitter metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtpbp1 ATP/GTP binding carboxypeptidase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr17:5,510,009...5,614,416
Ensembl chr17:5,511,385...5,614,435
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within ISO MGI:1933976 (MGI:3616353|PMID:16239221) RGD PMID:16239221 MGI:3616353 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Dynll1 dynein light chain LC8-type 1 involved_in TAS PMID:8864115 PINC PMID:8864115 RGD:633683 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Glul glutamate-ammonia ligase TAS RGD PMID:1674354 RGD:632694 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chat choline O-acetyltransferase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:126256, PMID:21873635, PMID:4008917, PMID:6854006, PMID:334962 RGD:2301195, RGD:13792537, RGD:2301203, RGD:2301199, RGD:2301197 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Slc44a4 solute carrier family 44, member 4 involved_in ISO
ISS
(PMID:23651124), (PMID:28013291)
GO_REF:0000024
RGD
UniProt
PMID:23651124 PMID:28013291 GO_REF:0000024 NCBI chr20:4,593,389...4,609,641
Ensembl chr20:4,593,389...4,609,631
JBrowse link
G Slc5a7 solute carrier family 5 member 7 involved_in
acts_upstream_of_or_within
IEA
ISO
IMP
IBA
GO_REF:0000107
MGI:3045463 (MGI:3044863|PMID:15173594)
PMID:10649566
(PMID:11068039)
PMID:21873635
Ensembl
RGD
PMID:11068039 PMID:15173594, PMID:10649566, PMID:21873635 GO_REF:0000107 MGI:3044863, RGD:68853, RGD:13792537 NCBI chr 9:5,294,377...5,330,822
Ensembl chr 9:5,294,381...5,330,815
JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in
acts_upstream_of_or_within
IDA
IEA
ISO
GO_REF:0000107
(MGI:3654414|PMID:16434405), (MGI:65815|PMID:7512968)
(PMID:1517212)
Ensembl
RGD
PMID:1517212 PMID:7512968 PMID:16434405, PMID:16052514, PMID:14646156, PMID:8737018, PMID:2731551, PMID:3655326, PMID:4008917, PMID:6854006, PMID:334962, PMID:126256, PMID:1133098 GO_REF:0000107 MGI:3654414 MGI:65815, RGD:1580870, RGD:2301213, RGD:2301207, RGD:2301205, RGD:2301204, RGD:2301203, RGD:2301199, RGD:2301197, RGD:2301195, RGD:2301187 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
acetylcholine catabolic process in synaptic cleft term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in IC PMID:26820598 SynGO PMID:26820598 RGD:12050110 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase IMP RGD PMID:16628397 RGD:1580871 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
histamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase involved_in ISO
ISS
(PMID:26206890)
GO_REF:0000024
RGD
UniProt
PMID:26206890 GO_REF:0000024 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
neurotransmitter biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 involved_in ISO (PMID:2925663) RGD PMID:2925663 NCBI chr13:85,580,828...85,597,497
Ensembl chr13:85,580,828...85,597,493
JBrowse link
G Chat choline O-acetyltransferase TAS RGD PMID:15477102 RGD:1358491 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Dagla diacylglycerol lipase, alpha involved_in
acts_upstream_of_or_within
IBA
ISO
ISS
PMID:21873635
MGI:4438719 (MGI:4437165|PMID:20147530)
(PMID:14610053)
GO_REF:0000024
RGD
UniProt
PMID:14610053 PMID:20147530, PMID:21873635 GO_REF:0000024 MGI:4437165, RGD:13792537 NCBI chr 1:226,297,013...226,353,712
Ensembl chr 1:226,297,016...226,353,611
JBrowse link
G Daglb diacylglycerol lipase, beta involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:3529581 (MGI:4437165|PMID:20147530)
GO_REF:0000107
RGD
Ensembl
PMID:20147530, PMID:21873635 GO_REF:0000107 MGI:4437165, RGD:13792537 NCBI chr12:13,113,073...13,157,748
Ensembl chr12:13,113,237...13,157,666
JBrowse link
G Gad1 glutamate decarboxylase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Th tyrosine hydroxylase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
neurotransmitter catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase involved_in IC PMID:10447691 UniProt PMID:10447691 RGD:631980 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180159 (MGI:3050939|PMID:15262267)
Ensembl
RGD
PMID:15262267 GO_REF:0000107 MGI:3050939 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:7,626,380...7,681,621
Ensembl chr16:7,627,603...7,681,576
JBrowse link
G Comt catechol-O-methyltransferase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:166,985,468...166,989,681
Ensembl chr 1:166,986,013...166,988,062
JBrowse link
G Maoa monoamine oxidase A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Maob monoamine oxidase B TAS
IDA
RGD PMID:12379239, PMID:18539264 RGD:633242, RGD:2316732 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 acts_upstream_of_or_within ISO (MGI:3043497|PMID:15086519), (MGI:5306875|PMID:21908619) RGD PMID:15086519 PMID:21908619 MGI:3043497 MGI:5306875 NCBI chr 8:17,453,198...17,525,906
Ensembl chr 8:17,454,122...17,525,906
JBrowse link
G Prima1 proline rich membrane anchor 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:127,075,954...127,127,985
Ensembl chr 6:127,075,954...127,127,413
JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,124,498...22,206,565
Ensembl chr 1:22,124,495...22,206,505
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
octopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase IMP RGD PMID:11521740 RGD:1625401 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 IDA RGD PMID:8888012 RGD:2302806 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO MGI:88392 (MGI:3628883|PMID:12204217) RGD PMID:12204217 MGI:3628883 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    metabolic process 11882
      cellular metabolic process 10839
        neurotransmitter metabolic process 29
          acetylcholine metabolic process + 6
          neurotransmitter biosynthetic process + 12
          neurotransmitter catabolic process + 11
          octopamine metabolic process + 3
          phenylethylamine metabolic process involved in synaptic transmission + 0
Path 2
Term Annotations click to browse term
  biological_process 19612
    biological regulation 13583
      regulation of biological quality 4254
        regulation of neurotransmitter levels 278
          neurotransmitter metabolic process 29
            acetylcholine metabolic process + 6
            neurotransmitter biosynthetic process + 12
            neurotransmitter catabolic process + 11
            octopamine metabolic process + 3
            phenylethylamine metabolic process involved in synaptic transmission + 0
paths to the root