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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cytokine biosynthetic process
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Accession:GO:0042036 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines.
Synonyms:exact_synonym: down regulation of cytokine biosynthetic process;   downregulation of cytokine biosynthetic process;   negative regulation of cytokine anabolism;   negative regulation of cytokine biosynthesis;   negative regulation of cytokine formation;   negative regulation of cytokine synthesis
 narrow_synonym: inhibition of cytokine biosynthetic process


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negative regulation of cytokine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Rnf128 ring finger protein 128 JBrowse link X 110,789,061 110,877,964 RGD:1624291
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein JBrowse link 4 118,207,845 118,238,246 RGD:1624291
negative regulation of chemokine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Sigirr single Ig and TIR domain containing JBrowse link 1 213,898,395 213,907,697 RGD:1624291
RGD:1600115
negative regulation of hepatocyte growth factor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Inhbb inhibin subunit beta B JBrowse link 13 35,436,532 35,442,222 RGD:1600115
RGD:1624291
negative regulation of tumor necrosis factor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl3 BCL3, transcription coactivator JBrowse link 1 80,730,758 80,745,273 RGD:1624291
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:9685562
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:1624291
RGD:1600115
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:1624291
RGD:1600115
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1598631
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    multicellular organismal process 8942
      cytokine production 840
        negative regulation of cytokine production 279
          negative regulation of cytokine biosynthetic process 13
            negative regulation of TRAIL biosynthetic process 0
            negative regulation of chemokine biosynthetic process 3
            negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 0
            negative regulation of hepatocyte growth factor biosynthetic process 1
            negative regulation of lymphotoxin A biosynthetic process 0
            negative regulation of tumor necrosis factor biosynthetic process 6
Path 2
Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      organic substance metabolic process 11359
        macromolecule metabolic process 9815
          gene expression 6046
            cytokine production 840
              regulation of cytokine production 757
                negative regulation of cytokine production 279
                  negative regulation of cytokine biosynthetic process 13
                    negative regulation of TRAIL biosynthetic process 0
                    negative regulation of chemokine biosynthetic process 3
                    negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 0
                    negative regulation of hepatocyte growth factor biosynthetic process 1
                    negative regulation of lymphotoxin A biosynthetic process 0
                    negative regulation of tumor necrosis factor biosynthetic process 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.