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ONTOLOGY REPORT - ANNOTATIONS


Term:protein refolding
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Accession:GO:0042026 term browser browse the term
Definition:The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
Synonyms:related_synonym: heat shock protein activity



show annotations for term's descendants           Sort by:
protein refolding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin acts_upstream_of_or_within ISO (PMID:16920948) RGD PMID:16920948 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Cryaa crystallin, alpha A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349
JBrowse link
G Cryab crystallin, alpha B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 involved_in ISO
IEA
IBA
(PMID:21231916)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:21231916 GO_REF:0000033 GO_REF:0000107 NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 involved_in ISO
IBA
(PMID:21231916)
GO_REF:0000033
RGD
GO_Central
PMID:21231916 GO_REF:0000033 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO
IBA
(PMID:21231916)
GO_REF:0000033
RGD
GO_Central
PMID:21231916 GO_REF:0000033 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277
JBrowse link
G ENSRNOG00000065699 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr14:100,606,613...100,607,588 JBrowse link
G Haus8l2 HAUS augmin-like complex, subunit 8 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:5,628,432...5,630,535
Ensembl chr11:5,628,427...5,630,533
JBrowse link
G Hsc70-ps1 heat shock cognate protein 70, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:164,044,226...164,046,344
Ensembl chr 2:164,044,261...164,046,336
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
JBrowse link
G Hspa14 heat shock protein family A (Hsp70) member 14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:74,728,945...74,749,727
Ensembl chr17:74,728,899...74,749,727
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO
ISS
IBA
(PMID:15603737), (PMID:21231916), (PMID:27708256)
GO_REF:0000024
GO_REF:0000033
RGD
UniProt
GO_Central
PMID:15603737 PMID:21231916 PMID:27708256 GO_REF:0000024 GO_REF:0000033 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:15603737), (PMID:21231916), (PMID:27708256)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:15603737 PMID:21231916 PMID:27708256 GO_REF:0000024 GO_REF:0000033 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like involved_in ISO
IBA
(PMID:21231916)
GO_REF:0000033
RGD
GO_Central
PMID:21231916 GO_REF:0000033 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 involved_in ISO
IBA
(PMID:21231916)
GO_REF:0000033
RGD
GO_Central
PMID:21231916 GO_REF:0000033 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISO
IBA
ISS
(PMID:21231916), (PMID:25719862)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
ParkinsonsUK-UCL
PMID:21231916 PMID:25719862 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspb2 heat shock protein family B (small) member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533
JBrowse link
G Hspb6 heat shock protein family B (small) member 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:85,806,898...85,809,072
Ensembl chr 1:85,806,146...85,809,071
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:11050098) RGD PMID:11050098 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hspd1l1 heat shock protein family D (Hsp60) member 1 like 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:1,587,931...1,590,330
Ensembl chr18:1,588,008...1,590,314
JBrowse link
negative regulation of protein refolding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in IMP PMID:15603737 BHF-UCL PMID:15603737 RGD:8553807 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
JBrowse link
G Pdcl phosducin like IDA RGD PMID:12060742 RGD:633730 NCBI chr 3:21,110,165...21,119,763
Ensembl chr 3:21,110,167...21,119,715
JBrowse link
G St13 ST13, Hsp70 interacting protein IDA RGD PMID:9183013 RGD:2326107 NCBI chr 7:112,891,007...112,925,727
Ensembl chr 7:112,844,375...112,925,945
JBrowse link
positive regulation of protein refolding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa8 heat shock protein family A (Hsp70) member 8 IDA RGD PMID:11360998 RGD:10059391 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      protein folding 221
        protein refolding 28
          negative regulation of protein refolding 3
          positive regulation of protein refolding 1
          regulation of protein refolding + 4
Path 2
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11455
      cellular metabolic process 9554
        cellular biosynthetic process 7841
          macromolecule biosynthetic process 7210
            gene expression 6770
              protein maturation 532
                protein folding 221
                  protein refolding 28
                    negative regulation of protein refolding 3
                    positive regulation of protein refolding 1
                    regulation of protein refolding + 4
paths to the root