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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA endoreduplication
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Accession:GO:0042023 term browser browse the term
Definition:Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
Comment:Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states.
Synonyms:exact_synonym: DNA endoreplication;   DNA re-duplication


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DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zpr1 ZPR1 zinc finger involved_in ISO (MGI:3575865|PMID:15767679) UniProt PMID:15767679 MGI:3575865 NCBI chrNW_004936542:2,058,048...2,067,468 JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) UniProt PMID:17875940 NCBI chrNW_004936489:5,589,621...5,602,221 JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 involved_in ISO (MGI:5449497|PMID:23064266) UniProt PMID:23064266 MGI:5449497 NCBI chrNW_004936568:5,206,135...5,245,324 JBrowse link
G E2f8 E2F transcription factor 8 involved_in ISO (MGI:5449497|PMID:23064266), (MGI:5449498|PMID:23064264) UniProt PMID:23064264 PMID:23064266 MGI:5449497 MGI:5449498 NCBI chrNW_004936654:322,863...339,365 JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (MGI:3831588|PMID:19090619) MGI PMID:19090619 MGI:3831588 NCBI chrNW_004936578:4,252,718...4,290,452 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12295
    cellular process 11513
      cell cycle process 995
        cell cycle DNA replication 25
          DNA endoreduplication 5
            negative regulation of DNA endoreduplication 1
            positive regulation of DNA endoreduplication 2
            regulation of DNA endoreduplication + 4
Path 2
Term Annotations click to browse term
  biological_process 12295
    metabolic process 7808
      organic substance metabolic process 7522
        macromolecule metabolic process 6479
          cellular macromolecule metabolic process 5525
            cellular macromolecule biosynthetic process 3236
              DNA replication 223
                DNA-dependent DNA replication 125
                  cell cycle DNA replication 25
                    DNA endoreduplication 5
                      negative regulation of DNA endoreduplication 1
                      positive regulation of DNA endoreduplication 2
                      regulation of DNA endoreduplication + 4
paths to the root