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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA endoreduplication
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Accession:GO:0042023 term browser browse the term
Definition:Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
Comment:Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states.
Synonyms:exact_synonym: DNA endoreplication;   DNA re-duplication


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DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zpr1 ZPR1 zinc finger involved_in ISO (MGI:3575865|PMID:15767679) UniProt PMID:15767679 MGI:3575865 NCBI chrNW_004955412:18,117,957...18,127,552
Ensembl chrNW_004955412:18,116,531...18,127,552
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) UniProt PMID:17875940 NCBI chrNW_004955439:8,830,658...8,843,653
Ensembl chrNW_004955439:8,830,975...8,843,828
JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 involved_in ISO (MGI:5449497|PMID:23064266) UniProt PMID:23064266 MGI:5449497 NCBI chrNW_004955405:16,148,640...16,187,272
Ensembl chrNW_004955405:16,148,480...16,186,282
JBrowse link
G E2f8 E2F transcription factor 8 involved_in ISO (MGI:5449497|PMID:23064266), (MGI:5449498|PMID:23064264) UniProt PMID:23064264 PMID:23064266 MGI:5449497 MGI:5449498 NCBI chrNW_004955476:197,699...215,227
Ensembl chrNW_004955476:197,630...213,441
JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (MGI:3831588|PMID:19090619) MGI PMID:19090619 MGI:3831588 NCBI chrNW_004955420:21,969,537...22,005,094
Ensembl chrNW_004955420:21,969,537...22,005,856
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12096
    cellular process 11356
      cell cycle process 983
        cell cycle DNA replication 24
          DNA endoreduplication 5
            negative regulation of DNA endoreduplication 1
            positive regulation of DNA endoreduplication 2
            regulation of DNA endoreduplication + 4
Path 2
Term Annotations click to browse term
  biological_process 12096
    metabolic process 7719
      organic substance metabolic process 7437
        macromolecule metabolic process 6416
          cellular macromolecule metabolic process 5475
            cellular macromolecule biosynthetic process 3213
              DNA replication 224
                DNA-dependent DNA replication 124
                  cell cycle DNA replication 24
                    DNA endoreduplication 5
                      negative regulation of DNA endoreduplication 1
                      positive regulation of DNA endoreduplication 2
                      regulation of DNA endoreduplication + 4
paths to the root