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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA endoreduplication
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Accession:GO:0042023 term browser browse the term
Definition:Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
Comment:Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states.
Synonyms:exact_synonym: DNA endoreplication;   DNA re-duplication
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe

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DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zpr1 ZPR1 zinc finger involved_in ISO (MGI:3575865|PMID:15767679) UniProt PMID:15767679 MGI:3575865 NCBI chrNW_004955412:18,117,957...18,127,552
Ensembl chrNW_004955412:18,116,531...18,127,552 		JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) UniProt PMID:17875940 NCBI chrNW_004955439:8,830,658...8,843,653
Ensembl chrNW_004955439:8,830,975...8,843,828 		JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 involved_in ISO (MGI:5449497|PMID:23064266) UniProt PMID:23064266 MGI:5449497 NCBI chrNW_004955405:16,148,640...16,187,272
Ensembl chrNW_004955405:16,148,480...16,186,282 		JBrowse link
G E2f8 E2F transcription factor 8 involved_in ISO (MGI:5449497|PMID:23064266), (MGI:5449498|PMID:23064264) UniProt PMID:23064264 PMID:23064266 MGI:5449497 MGI:5449498 NCBI chrNW_004955476:197,699...215,227
Ensembl chrNW_004955476:197,630...213,441 		JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (MGI:3831588|PMID:19090619) MGI PMID:19090619 MGI:3831588 NCBI chrNW_004955420:21,969,537...22,005,094
Ensembl chrNW_004955420:21,969,537...22,005,856 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12228
    cellular process 11398
      cell cycle process 1044
        cell cycle DNA replication 26
          DNA endoreduplication 5
            negative regulation of DNA endoreduplication 1
            positive regulation of DNA endoreduplication 2
            regulation of DNA endoreduplication + 4
Path 2
Term Annotations click to browse term
  biological_process 12228
    metabolic process 7369
      cellular metabolic process 6590
        cellular aromatic compound metabolic process 3859
          nucleobase-containing compound metabolic process 3673
            nucleic acid metabolic process 3346
              DNA metabolic process 784
                DNA replication 221
                  DNA-templated DNA replication 125
                    cell cycle DNA replication 26
                      DNA endoreduplication 5
                        negative regulation of DNA endoreduplication 1
                        positive regulation of DNA endoreduplication 2
                        regulation of DNA endoreduplication + 4
paths to the root