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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA endoreduplication
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Accession:GO:0042023 term browser browse the term
Definition:Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
Comment:Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states.
Synonyms:exact_synonym: DNA endoreplication;   DNA re-duplication



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DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZPR1 ZPR1 zinc finger involved_in ISO (MGI:3575865|PMID:15767679) UniProt PMID:15767679 MGI:3575865 NCBI chr11:111,613,940...111,623,539
Ensembl chr11:115,547,973...115,557,883
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO5 F-box protein 5 involved_in ISO (PMID:17875940) UniProt PMID:17875940 NCBI chr 6:150,793,020...150,806,008
Ensembl chr 6:155,481,753...155,494,231
JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2F7 E2F transcription factor 7 involved_in ISO (MGI:5449497|PMID:23064266) UniProt PMID:23064266 MGI:5449497 NCBI chr12:74,540,049...74,582,561
Ensembl chr12:77,388,950...77,433,262
JBrowse link
G E2F8 E2F transcription factor 8 involved_in ISO (MGI:5449497|PMID:23064266), (MGI:5449498|PMID:23064264) UniProt PMID:23064264 PMID:23064266 MGI:5449497 MGI:5449498 NCBI chr11:19,250,045...19,267,629
Ensembl chr11:19,162,837...19,179,744
JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SENP2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (MGI:3831588|PMID:19090619) MGI PMID:19090619 MGI:3831588 NCBI chr 3:182,606,922...182,655,518
Ensembl chr 3:191,086,488...191,129,572
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12786
    cellular process 11938
      cell cycle process 1019
        cell cycle DNA replication 26
          DNA endoreduplication 5
            negative regulation of DNA endoreduplication 1
            positive regulation of DNA endoreduplication 2
            regulation of DNA endoreduplication + 4
Path 2
Term Annotations click to browse term
  biological_process 12786
    metabolic process 8099
      organic substance metabolic process 7799
        macromolecule metabolic process 6695
          cellular macromolecule metabolic process 5678
            cellular macromolecule biosynthetic process 3322
              DNA replication 228
                DNA-dependent DNA replication 129
                  cell cycle DNA replication 26
                    DNA endoreduplication 5
                      negative regulation of DNA endoreduplication 1
                      positive regulation of DNA endoreduplication 2
                      regulation of DNA endoreduplication + 4
paths to the root