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ONTOLOGY REPORT - ANNOTATIONS


Term:single stranded viral RNA replication via double stranded DNA intermediate
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Accession:GO:0039692 term browser browse the term
Definition:A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II.
Synonyms:exact_synonym: retroviral genome replication
 related_synonym: viral ssRNA replication via dsDNA intermediate
 alt_id: GO:0045090
 xref: VZ:1937 "ssRNA(RT) replication/transcription"



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single stranded viral RNA replication via double stranded DNA intermediate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 acts_upstream_of_or_within ISO (PMID:14963118) RGD PMID:14963118 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620
JBrowse link
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Apobec3 apolipoprotein B mRNA editing enzyme catalytic subunit 3 involved_in IBA
ISO
PMID:21873635
(PMID:18779051), (PMID:21835787)
RGD PMID:18779051 PMID:21835787 PMID:21873635 RGD:13792537 NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO
ISS
(PMID:17005673)
GO_REF:0000024
RGD
UniProt
PMID:17005673 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:18774950) RGD PMID:18774950 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773
JBrowse link
G Morc2 MORC family CW-type zinc finger 2 involved_in ISO (PMID:29211708)
(MGI:6271895|PMID:29728365)
RGD PMID:29211708 PMID:29728365 MGI:6271895 NCBI chr14:78,529,603...78,571,375
Ensembl chr14:78,527,009...78,571,343
JBrowse link
G Mphosph8 M-phase phosphoprotein 8 involved_in ISO
ISS
(PMID:29211708)
GO_REF:0000024
RGD
UniProt
PMID:29211708 GO_REF:0000024 NCBI chr15:30,800,546...30,828,415 JBrowse link
G Resf1 retroelement silencing factor 1 involved_in ISO (MGI:6271895|PMID:29728365) RGD PMID:29728365 MGI:6271895 NCBI chr 4:182,325,913...182,362,054
Ensembl chr 4:182,335,454...182,362,054
JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 involved_in ISO (MGI:5440670|PMID:20164836), (MGI:6271895|PMID:29728365) RGD PMID:20164836 PMID:29728365 MGI:5440670 MGI:6271895 NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506
JBrowse link
G Tasor transcription activation suppressor involved_in ISO (PMID:29211708) RGD PMID:29211708 NCBI chr16:2,606,807...2,669,902
Ensembl chr16:2,603,936...2,667,292
JBrowse link
G Trim28 tripartite motif-containing 28 involved_in
acts_upstream_of_or_within
ISO (MGI:5440670|PMID:20164836)
MGI:2143362 (MGI:3842857|PMID:19270682)
RGD PMID:19270682 PMID:20164836 MGI:3842857 MGI:5440670 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
positive regulation of single stranded viral RNA replication via double stranded DNA intermediate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Top2a DNA topoisomerase II alpha involved_in IEA
ISO
GO_REF:0000107
(PMID:16712776)
Ensembl
RGD
PMID:16712776 GO_REF:0000107 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Top2b DNA topoisomerase II beta involved_in ISO (PMID:16712776) RGD PMID:16712776 NCBI chr15:9,051,661...9,111,220
Ensembl chr15:9,051,341...9,112,085
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19494
    viral process 341
      viral genome replication 122
        viral RNA genome replication 30
          single stranded viral RNA replication via double stranded DNA intermediate 13
            negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 10
            positive regulation of single stranded viral RNA replication via double stranded DNA intermediate 2
            regulation of single stranded viral RNA replication via double stranded DNA intermediate + 12
Path 2
Term Annotations click to browse term
  biological_process 19494
    viral process 341
      viral life cycle 258
        viral genome replication 122
          viral RNA genome replication 30
            single stranded viral RNA replication via double stranded DNA intermediate 13
              negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 10
              positive regulation of single stranded viral RNA replication via double stranded DNA intermediate 2
              regulation of single stranded viral RNA replication via double stranded DNA intermediate + 12
paths to the root