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ONTOLOGY REPORT - ANNOTATIONS


Term:TORC1 signaling
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Accession:GO:0038202 term browser browse the term
Definition:A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.
Synonyms:exact_synonym: TORC1 signal transduction


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TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Card11 caspase recruitment domain family, member 11 JBrowse link 12 15,700,600 15,844,512 RGD:1624291
G Larp1 La ribonucleoprotein 1, translational regulator JBrowse link 10 43,435,738 43,501,186 RGD:1624291
RGD:1600115
G Mfsd8 major facilitator superfamily domain containing 8 JBrowse link 2 127,706,618 127,784,129 RGD:1624291
RGD:1600115
G Mlst8 MTOR associated protein, LST8 homolog JBrowse link 10 13,839,250 13,845,001 RGD:1624291
RGD:1600115
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:1624291
RGD:13792537
G Nprl3 NPR3-like, GATOR1 complex subunit JBrowse link 10 15,620,824 15,661,332 RGD:13792537
G Rptor regulatory associated protein of MTOR, complex 1 JBrowse link 10 108,750,620 109,058,691 RGD:1624291
RGD:1600115
negative regulation of macroautophagy by TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec16a C-type lectin domain containing 16A JBrowse link 10 5,002,196 5,196,914 RGD:1624291
RGD:1600115
negative regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
RGD:13792537
G Bmt2 base methyltransferase of 25S rRNA 2 homolog JBrowse link 4 40,064,131 40,136,074 RGD:1624291
RGD:1600115
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 14 84,447,552 84,457,396 RGD:1624291
RGD:13792537
RGD:1600115
G Castor2 cytosolic arginine sensor for mTORC1 subunit 2 JBrowse link 12 25,595,800 25,638,806 RGD:1624291
RGD:13792537
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 14 83,089,000 83,219,576 RGD:1624291
G Fnip1 folliculin interacting protein 1 JBrowse link 10 39,786,687 39,870,188 RGD:1624291
G Fnip2 folliculin interacting protein 2 JBrowse link 2 178,223,561 178,334,925 RGD:1624291
RGD:1600115
G Itfg2 integrin alpha FG-GAP repeat containing 2 JBrowse link 4 161,730,643 161,744,281 RGD:1624291
RGD:1600115
G Kptn kaptin (actin binding protein) JBrowse link 1 78,015,714 78,016,508 RGD:1624291
G Kptn kaptin RGD:1600115
G RGD1565498 similar to Hypothetical protein LOC270802 JBrowse link 7 63,922,871 63,937,721 RGD:1624291
RGD:13792537
G Rnf152 ring finger protein 152 JBrowse link 13 25,183,295 25,262,785 RGD:1624291
RGD:1600115
G Sesn1 sestrin 1 JBrowse link 20 46,667,116 46,758,306 RGD:1624291
RGD:13792537
G Sesn2 sestrin 2 JBrowse link 5 150,684,891 150,703,846 RGD:1624291
RGD:13792537
G Sesn3 sestrin 3 JBrowse link 8 12,823,060 12,878,749 RGD:1624291
RGD:13792537
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:1624291
RGD:1600115
G Szt2 SZT2 subunit of KICSTOR complex JBrowse link 5 137,192,120 137,238,384 RGD:1624291
RGD:1600115
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:1624291
positive regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07041481.1 RGD:1600115
G Clec16a C-type lectin domain containing 16A JBrowse link 10 5,002,196 5,196,914 RGD:1624291
RGD:1600115
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:13792537
G Klhl22 kelch-like family member 22 JBrowse link 11 87,646,489 87,718,808 RGD:1600115
RGD:1624291
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 2 210,034,095 210,039,451 RGD:13792537
G Lars1 leucyl-tRNA synthetase 1 JBrowse link 18 36,524,013 36,579,471 RGD:1624291
RGD:1600115
G Pih1d1 PIH1 domain containing 1 JBrowse link 1 101,151,240 101,156,806 RGD:1624291
RGD:1600115
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 JBrowse link 15 27,852,152 27,855,999 RGD:1624291
RGD:1600115
G Rraga Ras-related GTP binding A JBrowse link 5 104,941,067 104,942,662 RGD:1624291
RGD:1600115
G RragB Ras-related GTP binding B JBrowse link X 19,085,913 19,135,049 RGD:1624291
G Rragd Ras-related GTP binding D JBrowse link 5 48,224,994 48,260,691 RGD:1624291
RGD:1600115
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 4 145,686,186 145,699,577 RGD:1600115
G Seh1l SEH1-like nucleoporin JBrowse link 18 63,545,150 63,568,101 RGD:1624291
G Sik3 SIK family kinase 3 JBrowse link 8 50,310,263 50,520,284 RGD:1600115
RGD:1624291
G Telo2 telomere maintenance 2 JBrowse link 10 14,461,581 14,476,812 RGD:1624291
RGD:1600115
regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgkq diacylglycerol kinase, theta JBrowse link 14 2,069,409 2,083,370 RGD:1624291
RGD:1600115
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link 13 47,906,230 47,916,877 RGD:1600115
RGD:1624291
G RGD1359108 similar to RIKEN cDNA 3110043O21 JBrowse link 5 50,666,444 50,691,523 RGD:1600115
RGD:1624291
G Rraga Ras-related GTP binding A JBrowse link 5 104,941,067 104,942,662 RGD:1600115
G Rragc Ras-related GTP binding C JBrowse link 5 141,572,536 141,590,784 RGD:1624291
RGD:1600115
G Smcr8 SMCR8-C9orf72 complex subunit JBrowse link 10 47,019,326 47,026,465 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    signaling 7394
      signal transduction 6875
        intracellular signal transduction 2629
          TOR signaling 127
            TORC1 signaling 45
              negative regulation of TORC1 signaling 18
              negative regulation of macroautophagy by TORC1 signaling 1
              positive regulation of TORC1 signaling 15
              regulation of TORC1 signaling + 38
Path 2
Term Annotations click to browse term
  biological_process 19317
    biological regulation 13340
      regulation of biological process 12656
        regulation of cellular process 11981
          signal transduction 6875
            intracellular signal transduction 2629
              TOR signaling 127
                TORC1 signaling 45
                  negative regulation of TORC1 signaling 18
                  negative regulation of macroautophagy by TORC1 signaling 1
                  positive regulation of TORC1 signaling 15
                  regulation of TORC1 signaling + 38
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.