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ONTOLOGY REPORT - ANNOTATIONS


Term:TOR complex
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Accession:GO:0038201 term browser browse the term
Definition:A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and activation of downstream signaling components including PKB (AKT) or S6K.
Synonyms:exact_synonym: TOR signaling complex;   target of rapamycin complex
 narrow_synonym: mTOR complex


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TORC1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1s1 AKT1 substrate 1 colocalizes_with
part_of
ISO
IEA
(PMID:17386266)
GO_REF:0000107
RGD
Ensembl
PMID:17386266 GO_REF:0000107 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator colocalizes_with ISO (PMID:24532714), (PMID:25940091) RGD PMID:24532714 PMID:25940091 NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371
JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog part_of ISO
IEA
IBA
(PMID:12718876), (PMID:24036451)
GO_REF:0000107
(MGI:5816448|PMID:12718876)
PMID:21873635
RGD
Ensembl
PMID:12718876 PMID:24036451 PMID:21873635 GO_REF:0000107 MGI:5816448, RGD:13792537 NCBI chr10:13,498,377...13,504,128
Ensembl chr10:13,498,388...13,504,128
JBrowse link
G Mtor mechanistic target of rapamycin kinase part_of IDA
ISO
IBA
(PMID:12150926), (PMID:12718876), (PMID:15467718), (PMID:18925875), (PMID:20537536)
(MGI:5816448|PMID:12718876)
PMID:21873635
RGD PMID:12150926 PMID:12718876 PMID:15467718 PMID:18925875 PMID:20537536 More... MGI:5816448, RGD:2307383, RGD:13792537 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 part_of ISO
IBA
(PMID:12150926), (PMID:12718876), (PMID:15467718), (PMID:24036451), (PMID:25940091)
PMID:21873635
RGD PMID:12150926 PMID:12718876 PMID:15467718 PMID:24036451 PMID:25940091 More... RGD:13792537 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
G Telo2 telomere maintenance 2 part_of ISO (PMID:23263282) RGD PMID:23263282 NCBI chr10:14,120,491...14,135,729
Ensembl chr10:14,120,818...14,135,698
JBrowse link
G Tti1 TELO2 interacting protein 1 part_of ISO (PMID:23263282) RGD PMID:23263282 NCBI chr 3:146,639,048...146,682,945
Ensembl chr 3:146,639,054...146,682,847
JBrowse link
TORC2 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07051501.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Mapkap1 MAPK associated protein 1 part_of IBA
ISO
PMID:21873635
(MGI:3759333|PMID:16962653)
RGD PMID:16962653 PMID:21873635 MGI:3759333, RGD:13792537 NCBI chr 3:17,715,813...17,918,387
Ensembl chr 3:17,715,834...17,918,384
JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog part_of ISO
IEA
IBA
(PMID:24036451)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:24036451 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:13,498,377...13,504,128
Ensembl chr10:13,498,388...13,504,128
JBrowse link
G Mtor mechanistic target of rapamycin kinase part_of IBA
ISO
PMID:21873635
(PMID:15467718), (PMID:18925875)
RGD PMID:15467718 PMID:18925875 PMID:21873635 RGD:13792537 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Prr5 proline rich 5 part_of ISO
IEA
IBA
(PMID:22609986)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:22609986 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 7:115,795,351...115,837,880
Ensembl chr 7:115,813,954...115,834,834
JBrowse link
G Prr5l proline rich 5 like part_of ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:22609986)
UniProt
Ensembl
RGD
PMID:22609986 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 3:88,001,951...88,173,532
Ensembl chr 3:88,003,617...88,082,763
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 part_of ISO
IBA
(PMID:15268862), (PMID:15467718), (PMID:24036451)
(MGI:3759333|PMID:16962653)
PMID:21873635
RGD PMID:15268862 PMID:15467718 PMID:16962653 PMID:24036451 PMID:21873635 MGI:3759333, RGD:13792537 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Sesn2 sestrin 2 part_of ISO (MGI:5779633|PMID:25377878) RGD PMID:25377878 MGI:5779633 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sesn3 sestrin 3 part_of ISO (MGI:5779633|PMID:25377878) RGD PMID:25377878 MGI:5779633 NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842
JBrowse link
G Telo2 telomere maintenance 2 part_of ISO (PMID:23263282) RGD PMID:23263282 NCBI chr10:14,120,491...14,135,729
Ensembl chr10:14,120,818...14,135,698
JBrowse link
G Tti1 TELO2 interacting protein 1 part_of ISO (PMID:23263282) RGD PMID:23263282 NCBI chr 3:146,639,048...146,682,945
Ensembl chr 3:146,639,054...146,682,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20010
    protein-containing complex 6011
      intracellular protein-containing complex 775
        TOR complex 14
          TORC1 complex 7
          TORC2 complex 11
paths to the root