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ONTOLOGY REPORT - ANNOTATIONS

Term:pattern recognition receptor activity
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Accession:GO:0038187 term browser browse the term
Definition:Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.
Synonyms:exact_synonym: PRR;   PRR activity
 narrow_synonym: MAMP receptor activity;   PAMP receptor activity;   microbe-associated molecular pattern receptor activity;   pathogen associated molecular pattern receptor activity
 related_synonym: macrophage receptor activity;   signaling pattern recognition receptor activity
 alt_id: GO:0008329
 xref: Wikipedia:Pattern_recognition_receptor


show annotations for term's descendants           Sort by:
pattern recognition receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC4E C-type lectin domain family 4 member E enables ISO (PMID:24101491)
(MGI:4415080|PMID:20008526)
(MGI:3796003|PMID:18490740)		 UniProt PMID:18490740 PMID:20008526 PMID:24101491 MGI:3796003 MGI:4415080 NCBI chr 5:63,219,229...63,228,566 JBrowse link
G CLEC7A C-type lectin domain containing 7A enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:61,832,910...61,846,441
Ensembl chr 5:61,832,954...61,846,434 		JBrowse link
G COLEC12 collectin subfamily member 12 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:105,808,157...106,000,197
Ensembl chr 6:105,808,221...106,007,730 		JBrowse link
G DHX16 DEAH-box helicase 16 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:23,190,645...23,208,071
Ensembl chr 7:23,189,774...23,208,062 		JBrowse link
G DMBT1 deleted in malignant brain tumors 1 enables ISO (PMID:19189310) UniProt PMID:19189310 NCBI chr14:132,154,346...132,231,274 JBrowse link
G FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) enables ISO (PMID:21037097) UniProt PMID:21037097 NCBI chr 1:274,106,276...274,111,970
Ensembl chr 1:274,103,877...274,111,970 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 enables IEA Ensembl GO_REF:0000107 NCBI chr15:68,930,998...68,985,145
Ensembl chr15:68,928,254...68,985,083 		JBrowse link
G LOC110258710 C-type lectin domain family 4 member D-like enables ISO (PMID:23911656) UniProt PMID:23911656
G LOC733579 tripartite motif protein TRIM5 enables ISO (PMID:21512573) UniProt PMID:21512573 NCBI chr 9:4,157,290...4,170,233
Ensembl chr 9:4,157,290...4,170,204 		JBrowse link
G NLRP1 NLR family pyrin domain containing 1 enables ISO (PMID:33243852) UniProt PMID:33243852 NCBI chr12:51,479,968...51,495,540 JBrowse link
G NLRP6 NLR family pyrin domain containing 6 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:90,001...97,441
Ensembl chr 2:90,027...97,439 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 enables ISO (PMID:11058605), (PMID:12791997), (PMID:12796777), (PMID:12871942), (PMID:23300079), (PMID:31649195), (PMID:33942347)
(MGI:6210191|PMID:27007849), (PMID:18261938)		 UniProt
MGI		 PMID:11058605 PMID:12791997 PMID:12796777 PMID:12871942 PMID:18261938 More... MGI:6210191 NCBI chr18:42,464,667...42,509,135
Ensembl chr18:42,432,050...42,512,264 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G RIGI RNA sensor RIG-I enables IEA Ensembl GO_REF:0000107 NCBI chr10:33,891,720...33,976,151
Ensembl chr10:33,891,763...33,933,455 		JBrowse link
G TLR2 toll like receptor 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TLR3 toll like receptor 3 enables IEA Ensembl GO_REF:0000107 NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,969,006...46,979,291 		JBrowse link
G TLR5 toll like receptor 5 enables ISO (PMID:14625549), (PMID:17128265) UniProt PMID:14625549 PMID:17128265 NCBI chr10:19,387,666...19,410,024
Ensembl chr10:19,387,666...19,410,024 		JBrowse link
G TLR9 toll like receptor 9 enables ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673 		JBrowse link
(1->3)-beta-D-glucan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A enables ISO (PMID:12719478) MGI PMID:12719478 NCBI chr 5:61,832,910...61,846,441
Ensembl chr 5:61,832,954...61,846,434 		JBrowse link
lipopolysaccharide immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule enables IEA Ensembl GO_REF:0000107 NCBI chr 2:142,348,036...142,349,686
Ensembl chr 2:142,346,360...142,349,581 		JBrowse link
G LY96 lymphocyte antigen 96 enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:61,919,806...61,950,712
Ensembl chr 4:61,926,064...61,950,697 		JBrowse link
G PTAFR platelet activating factor receptor enables IEA Ensembl GO_REF:0000107 NCBI chr 6:85,235,390...85,272,360
Ensembl chr 6:85,235,394...85,261,760 		JBrowse link
G SCARB1 scavenger receptor class B member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr14:28,301,421...28,393,568
Ensembl chr14:28,301,294...28,393,568 		JBrowse link
G TLR4 toll like receptor 4 enables IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
lipoteichoic acid immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule enables ISO (PMID:16061696) MGI PMID:16061696 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105 		JBrowse link
peptidoglycan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGLYRP1 peptidoglycan recognition protein 1 enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:52,318,544...52,322,504
Ensembl chr 6:52,318,531...52,322,638 		JBrowse link
G PGLYRP2 peptidoglycan recognition protein 2 enables IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:62,135,578...62,140,180
Ensembl chr 2:62,134,533...62,140,184 		JBrowse link
G PGLYRP3 peptidoglycan recognition protein 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:96,261,753...96,277,521
Ensembl chr 4:96,261,775...96,277,521 		JBrowse link
G PGLYRP4 peptidoglycan recognition protein 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:96,243,174...96,247,517
Ensembl chr 4:96,243,118...96,261,495 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18629
    molecular transducer activity 2565
      signaling receptor activity 2565
        pattern recognition receptor activity 28
          lipoarabinomannan immune receptor activity 0
          lipopolysaccharide immune receptor activity 5
          lipoteichoic acid immune receptor activity 1
          peptidoglycan immune receptor activity 4
          polysaccharide immune receptor activity + 1
paths to the root