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ONTOLOGY REPORT - ANNOTATIONS

Term:pattern recognition receptor activity
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Accession:GO:0038187 term browser browse the term
Definition:Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.
Synonyms:exact_synonym: PRR;   PRR activity
 narrow_synonym: MAMP receptor activity;   PAMP receptor activity;   microbe-associated molecular pattern receptor activity;   pathogen associated molecular pattern receptor activity
 related_synonym: macrophage receptor activity;   signaling pattern recognition receptor activity
 alt_id: GO:0008329
 xref: Wikipedia:Pattern_recognition_receptor


show annotations for term's descendants           Sort by:
pattern recognition receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 enables ISO
IDA		 (PMID:23567559), (PMID:27846608), (PMID:32350463) MGI
UniProt		 PMID:23567559 PMID:27846608 PMID:32350463 GO_REF:0000119 MGI:4834177 NCBI chr 1:173,177,105...173,293,606
Ensembl chr 1:173,178,445...173,293,606 		JBrowse link
G Clec4d C-type lectin domain family 4, member d enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:123,239,066...123,252,227
Ensembl chr 6:123,239,070...123,252,224 		JBrowse link
G Clec4e C-type lectin domain family 4, member e enables IDA
ISO
IMP		 (MGI:4415080|PMID:20008526)
(MGI:3796003|PMID:18490740)		 UniProt
MGI		 PMID:18490740 PMID:20008526 GO_REF:0000119 MGI:3796003 MGI:4415080 MGI:4834177 NCBI chr 6:123,258,748...123,266,830
Ensembl chr 6:123,258,748...123,266,829 		JBrowse link
G Clec4n C-type lectin domain family 4, member n enables IMP
ISO		 (MGI:5300086|PMID:22041900) ARUK-UCL
MGI		 PMID:22041900 GO_REF:0000119 MGI:4834177 MGI:5300086 NCBI chr 6:123,206,802...123,223,983
Ensembl chr 6:123,206,802...123,223,980 		JBrowse link
G Clec7a C-type lectin domain family 7, member a enables IMP
IBA
ISO
IDA		 (MGI:3045647|PMID:15213161), (MGI:3694815|PMID:17159984)
(MGI:3844414|PMID:19136564)		 UniProt
GO_Central
MGI
ARUK-UCL		 PMID:15213161 PMID:17159984 PMID:19136564 GO_REF:0000033 GO_REF:0000119 MGI:3045647 MGI:3694815 MGI:3844414 MGI:4834177 NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742 		JBrowse link
G Colec12 collectin sub-family member 12 enables ISS
ISO		 (MGI:2153597|PMID:11564734) UniProt
MGI		 PMID:11564734 GO_REF:0000119 MGI:2153597 MGI:4834177 NCBI chr18:9,707,648...9,877,995
Ensembl chr18:9,707,595...9,882,644 		JBrowse link
G Dhx16 DEAH-box helicase 16 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:36,190,657...36,203,562
Ensembl chr17:36,190,711...36,203,562 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:130,633,787...130,723,357
Ensembl chr 7:130,633,776...130,723,357 		JBrowse link
G Fcnb ficolin B enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:27,966,491...27,974,921
Ensembl chr 2:27,966,390...27,974,897 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:62,426,137...62,476,599
Ensembl chr 2:62,426,142...62,476,599 		JBrowse link
G Klrh1 killer cell lectin-like receptor subfamily H, member 1 enables IBA GO_Central GO_REF:0000033 NCBI chr 6:129,743,531...129,761,233
Ensembl chr 6:129,743,531...129,761,233 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:70,982,023...71,035,780
Ensembl chr11:70,983,062...71,035,530 		JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:71,043,400...71,133,340
Ensembl chr11:71,043,928...71,121,559 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 enables IDA
ISO		 (MGI:6833928|PMID:34678144) UniProt
MGI		 PMID:34678144 GO_REF:0000119 MGI:4834177 MGI:6833928 NCBI chr 7:140,500,777...140,509,105
Ensembl chr 7:140,500,815...140,509,105 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 enables ISO
IDA		 (MGI:6210191|PMID:27007849), (PMID:18261938) MGI PMID:18261938 PMID:27007849 GO_REF:0000119 MGI:4834177 MGI:6210191 NCBI chr 6:54,900,927...54,949,655
Ensembl chr 6:54,900,934...54,949,597 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 enables IMP
IDA
ISO		 (MGI:5763542|PMID:25429073)
(MGI:6210191|PMID:27007849), (PMID:18261938)
(PMID:22033934)		 UniProt
MGI		 PMID:18261938 PMID:22033934 PMID:25429073 PMID:27007849 GO_REF:0000119 MGI:4834177 MGI:5763542 MGI:6210191 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Rigi RNA sensor RIG-I enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:40,203,775...40,239,843
Ensembl chr 4:40,203,773...40,239,828 		JBrowse link
G Tlr2 toll-like receptor 2 enables ISO
IMP		 (PMID:22033934) MGI PMID:22033934 GO_REF:0000119 MGI:4834177 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr3 toll-like receptor 3 enables ISO
IDA
IMP
IGI		 (PMID:16260493)
(PMID:12855817)		 MGI PMID:12855817 PMID:16260493 GO_REF:0000119 MGI:4834177 NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117 		JBrowse link
G Tlr5 toll-like receptor 5 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:182,782,317...182,804,010
Ensembl chr 1:182,782,353...182,804,010 		JBrowse link
G Tlr7 toll-like receptor 7 enables IBA GO_Central GO_REF:0000033 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554 		JBrowse link
G Tlr8 toll-like receptor 8 enables IBA GO_Central GO_REF:0000033 NCBI chr  X:166,024,119...166,047,325
Ensembl chr  X:166,025,692...166,047,325 		JBrowse link
G Tlr9 toll-like receptor 9 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Trim12a tripartite motif-containing 12A enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:103,949,100...103,964,765
Ensembl chr 7:103,949,101...103,964,673 		JBrowse link
G Trim12c tripartite motif-containing 12C enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:103,987,961...104,002,649
Ensembl chr 7:103,987,961...104,002,569 		JBrowse link
G Trim30a tripartite motif-containing 30A enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:104,058,232...104,114,400
Ensembl chr 7:104,058,232...104,114,400 		JBrowse link
G Trim30b tripartite motif-containing 30B enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:104,004,605...104,007,853
Ensembl chr 7:104,004,589...104,019,091 		JBrowse link
G Trim30c tripartite motif-containing 30C enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:104,028,324...104,050,059
Ensembl chr 7:104,031,272...104,050,044 		JBrowse link
G Trim30d tripartite motif-containing 30D enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:104,119,221...104,157,062
Ensembl chr 7:104,119,221...104,157,056 		JBrowse link
G Trim5 tripartite motif-containing 5 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:103,912,593...103,937,448
Ensembl chr 7:103,912,593...103,937,301 		JBrowse link
(1->3)-beta-D-glucan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain family 7, member a enables IDA (PMID:12719478) MGI PMID:12719478 NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742 		JBrowse link
lipopolysaccharide immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 antigen enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Ly96 lymphocyte antigen 96 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 1:16,758,680...16,779,829
Ensembl chr 1:16,758,275...16,779,835 		JBrowse link
G Ptafr platelet-activating factor receptor enables IMP (PMID:9013981) MGI PMID:9013981 NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
G Tlr4 toll-like receptor 4 enables ISO
IBA
IDA		 (MGI:5913054|PMID:28098138), (PMID:16260493), (PMID:18261938) MGI
GO_Central
UniProt		 PMID:16260493 PMID:18261938 PMID:28098138 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:5913054 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
lipoteichoic acid immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule enables IMP (PMID:16061696) MGI PMID:16061696 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
peptidoglycan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pglyrp1 peptidoglycan recognition protein 1 enables ISO
IBA		 (PMID:11461926) MGI
GO_Central		 PMID:11461926 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 7:18,618,615...18,624,363
Ensembl chr 7:18,605,256...18,624,384 		JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 enables ISO
IBA		 (PMID:11461926) MGI
GO_Central		 PMID:11461926 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr17:32,631,433...32,643,157
Ensembl chr17:32,631,433...32,643,141 		JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:91,919,784...91,939,979
Ensembl chr 3:91,921,890...91,938,889 		JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:90,634,008...90,648,824
Ensembl chr 3:90,634,213...90,648,824 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28837
    molecular transducer activity 2463
      signaling receptor activity 2463
        pattern recognition receptor activity 40
          lipoarabinomannan immune receptor activity 0
          lipopolysaccharide immune receptor activity 5
          lipoteichoic acid immune receptor activity 1
          peptidoglycan immune receptor activity 4
          polysaccharide immune receptor activity + 1
paths to the root