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ONTOLOGY REPORT - ANNOTATIONS

Term:pattern recognition receptor activity
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Accession:GO:0038187 term browser browse the term
Definition:Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.
Synonyms:exact_synonym: PRR;   PRR activity
 narrow_synonym: MAMP receptor activity;   PAMP receptor activity;   microbe-associated molecular pattern receptor activity;   pathogen associated molecular pattern receptor activity
 related_synonym: macrophage receptor activity;   signaling pattern recognition receptor activity
 alt_id: GO:0008329
 xref: Wikipedia:Pattern_recognition_receptor


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pattern recognition receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIM2 absent in melanoma 2 enables IDA
IEA		 (PMID:26197926) UniProt
Ensembl		 PMID:26197926 GO_REF:0000107 NCBI chr 1:159,055,051...159,147,132
Ensembl chr 1:159,061,599...159,187,843 		JBrowse link
G CARD8 caspase recruitment domain family member 8 enables IDA (PMID:33542150) UniProt PMID:33542150 NCBI chr19:48,203,148...48,255,946
Ensembl chr19:48,180,770...48,255,946 		JBrowse link
G CLEC4D C-type lectin domain family 4 member D enables IDA (PMID:23911656) UniProt PMID:23911656 NCBI chr12:8,513,503...8,531,696
Ensembl chr12:8,509,475...8,522,366 		JBrowse link
G CLEC4E C-type lectin domain family 4 member E enables IDA
IEA		 (PMID:24101491) UniProt
Ensembl		 PMID:24101491 GO_REF:0000107 NCBI chr12:8,533,275...8,540,905
Ensembl chr12:8,533,305...8,540,905 		JBrowse link
G CLEC6A C-type lectin domain containing 6A enables IEA
IDA
ISS		 (PMID:23911656) Ensembl
UniProt
ARUK-UCL		 PMID:23911656 GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,455,962...8,478,330
Ensembl chr12:8,455,962...8,478,330 		JBrowse link
G CLEC7A C-type lectin domain containing 7A enables IDA
IBA
ISS		 (PMID:11567029) UniProt
GO_Central
ARUK-UCL		 PMID:11567029 GO_REF:0000024 GO_REF:0000033 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G COLEC12 collectin subfamily member 12 enables IDA
IBA		 (PMID:11564734) UniProt
GO_Central		 PMID:11564734 GO_REF:0000033 NCBI chr18:316,737...500,701
Ensembl chr18:316,737...500,722 		JBrowse link
G DHX16 DEAH-box helicase 16 enables IDA (PMID:35263596) UniProt PMID:35263596 NCBI chr 6:30,653,127...30,673,006
Ensembl chr 6:30,653,119...30,673,006 		JBrowse link
G DMBT1 deleted in malignant brain tumors 1 enables TAS
IDA		 (PMID:12681477)
(PMID:19189310)		 UniProt PMID:12681477 PMID:19189310 NCBI chr10:122,560,754...122,643,736
Ensembl chr10:122,560,665...122,643,736 		JBrowse link
G FCN1 ficolin 1 enables IMP (PMID:21037097) UniProt PMID:21037097 NCBI chr 9:134,903,232...134,917,912
Ensembl chr 9:134,903,232...134,917,912 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 enables IDA (PMID:21217758), (PMID:23273991) UniProt PMID:21217758 PMID:23273991 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684 		JBrowse link
G MARCO macrophage receptor with collagenous structure enables TAS (PMID:10331948) PINC PMID:10331948 NCBI chr 2:118,942,194...118,994,660
Ensembl chr 2:118,942,194...118,994,660 		JBrowse link
G NLRP1 NLR family pyrin domain containing 1 enables IDA (PMID:33243852) UniProt PMID:33243852 NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
G NLRP6 NLR family pyrin domain containing 6 enables IDA
IEA		 (PMID:31932628), (PMID:33377178), (PMID:34678144) UniProt
Ensembl		 PMID:31932628 PMID:33377178 PMID:34678144 GO_REF:0000107 NCBI chr11:278,407...285,388
Ensembl chr11:278,407...285,388 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 enables IDA
IEA		 (PMID:11058605), (PMID:12791997), (PMID:12796777), (PMID:12871942), (PMID:23300079), (PMID:31649195), (PMID:33942347) UniProt
Ensembl		 PMID:11058605 PMID:12791997 PMID:12796777 PMID:12871942 PMID:23300079 More... GO_REF:0000107 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 enables IDA
IEA		 (PMID:12871942), (PMID:17355968), (PMID:22857257), (PMID:23300079), (PMID:27748583), (PMID:31649195), (PMID:33942347) UniProt
Ensembl		 PMID:12871942 PMID:17355968 PMID:22857257 PMID:23300079 PMID:27748583 More... GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G RIGI RNA sensor RIG-I enables IDA (PMID:19576794), (PMID:25119032), (PMID:28469175), (PMID:35263596) UniProt PMID:19576794 PMID:25119032 PMID:28469175 PMID:35263596 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,348 		JBrowse link
G TLR2 toll like receptor 2 enables IDA (PMID:10384090) UniProt PMID:10384090 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR3 toll like receptor 3 enables IDA
IEA		 (PMID:16720699), (PMID:17128265) UniProt
Ensembl		 PMID:16720699 PMID:17128265 GO_REF:0000107 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR5 toll like receptor 5 enables IDA (PMID:14625549), (PMID:17128265) UniProt PMID:14625549 PMID:17128265 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,292 		JBrowse link
G TLR7 toll like receptor 7 enables IBA GO_Central GO_REF:0000033 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR8 toll like receptor 8 enables IBA GO_Central GO_REF:0000033 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
G TLR9 toll like receptor 9 enables IDA
IBA		 (PMID:14716310), (PMID:17128265) BHF-UCL
GO_Central		 PMID:14716310 PMID:17128265 GO_REF:0000033 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TRIM5 tripartite motif containing 5 enables IDA (PMID:21512573) UniProt PMID:21512573 NCBI chr11:5,588,635...5,685,074
Ensembl chr11:5,663,195...5,938,619 		JBrowse link
(1->3)-beta-D-glucan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A enables ISO (PMID:12719478) MGI PMID:12719478 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
lipopolysaccharide immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule enables IDA (PMID:15294986) AgBase PMID:15294986 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G LY96 lymphocyte antigen 96 enables IDA
IBA		 (PMID:19252480) UniProt
GO_Central		 PMID:19252480 GO_REF:0000033 NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079 		JBrowse link
G PTAFR platelet activating factor receptor enables IEA Ensembl GO_REF:0000107 NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936 		JBrowse link
G SCARB1 scavenger receptor class B member 1 enables IDA (PMID:12651854) BHF-UCL PMID:12651854 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668 		JBrowse link
G TLR2 toll like receptor 2 enables TAS (PMID:11518816) UniProt PMID:11518816 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 enables IDA
NAS
IBA		 (PMID:19252480)
(PMID:11970998)		 UniProt
GO_Central		 PMID:11970998 PMID:19252480 GO_REF:0000033 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
lipoteichoic acid immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule (CD36 blood group) enables IEA Ensembl GO_REF:0000107 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
peptidoglycan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule enables TAS (PMID:8798531) PINC PMID:8798531 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G PGLYRP1 peptidoglycan recognition protein 1 enables IDA
IBA		 (PMID:11461926) UniProt
GO_Central		 PMID:11461926 GO_REF:0000033 NCBI chr19:46,019,153...46,023,053
Ensembl chr19:46,019,153...46,023,053 		JBrowse link
G PGLYRP2 peptidoglycan recognition protein 2 enables IDA
IBA		 (PMID:11461926) UniProt
GO_Central		 PMID:11461926 GO_REF:0000033 NCBI chr19:15,468,645...15,479,501
Ensembl chr19:15,468,645...15,498,956 		JBrowse link
G PGLYRP3 peptidoglycan recognition protein 3 enables IDA (PMID:11461926) UniProt PMID:11461926 NCBI chr 1:153,297,116...153,312,952
Ensembl chr 1:153,297,116...153,312,952 		JBrowse link
G PGLYRP4 peptidoglycan recognition protein 4 enables IDA (PMID:11461926) UniProt PMID:11461926 NCBI chr 1:153,330,120...153,348,841
Ensembl chr 1:153,330,120...153,348,841 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19583
    molecular transducer activity 1596
      signaling receptor activity 1596
        pattern recognition receptor activity 34
          lipoarabinomannan immune receptor activity 0
          lipopolysaccharide immune receptor activity 6
          lipoteichoic acid immune receptor activity 1
          peptidoglycan immune receptor activity 5
          polysaccharide immune receptor activity + 1
paths to the root