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ONTOLOGY REPORT - ANNOTATIONS

Term:pattern recognition receptor activity
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Accession:GO:0038187 term browser browse the term
Definition:Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.
Synonyms:exact_synonym: PRR;   PRR activity
 narrow_synonym: MAMP receptor activity;   PAMP receptor activity;   microbe-associated molecular pattern receptor activity;   pathogen associated molecular pattern receptor activity
 related_synonym: macrophage receptor activity;   signaling pattern recognition receptor activity
 alt_id: GO:0008329
 xref: Wikipedia:Pattern_recognition_receptor

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pattern recognition receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIM2 absent in melanoma 2 enables IEA Ensembl GO_REF:0000107 NCBI chr20:4,759,746...4,884,460
Ensembl chr20:4,873,008...4,884,764 		JBrowse link
G CLEC4D C-type lectin domain family 4 member D enables ISO (PMID:23911656) UniProt PMID:23911656 NCBI chr11:8,294,999...8,303,866 JBrowse link
G CLEC4D C-type lectin domain family 4 member D enables IEA Ensembl GO_REF:0000107 Ensembl chr11:8,297,155...8,302,780 JBrowse link
G CLEC4E C-type lectin domain family 4 member E enables ISO (PMID:24101491)
(MGI:3796003|PMID:18490740)
(MGI:4415080|PMID:20008526)		 UniProt PMID:18490740 PMID:20008526 PMID:24101491 MGI:3796003 MGI:4415080 NCBI chr11:8,315,888...8,322,240
Ensembl chr11:8,316,049...8,321,274 		JBrowse link
G CLEC6A C-type lectin domain containing 6A enables IEA Ensembl GO_REF:0000107 NCBI chr11:8,227,590...8,250,857
Ensembl chr11:8,228,381...8,253,159 		JBrowse link
G CLEC7A C-type lectin domain containing 7A enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:9,989,520...10,007,442
Ensembl chr11:9,995,203...10,006,746 		JBrowse link
G COLEC12 collectin subfamily member 12 enables IEA Ensembl GO_REF:0000107 NCBI chr18:59,701,131...59,884,445
Ensembl chr18:59,699,348...59,884,461 		JBrowse link
G DHX16 DEAH-box helicase 16 enables IEA Ensembl GO_REF:0000107 NCBI chr17:41,780,965...41,801,310
Ensembl chr17:41,780,987...41,801,219 		JBrowse link
G DMBT1 deleted in malignant brain tumors 1 enables ISO (PMID:19189310) UniProt PMID:19189310 NCBI chr 9:115,344,861...115,346,308 JBrowse link
G FCN1 ficolin 1 enables ISO (PMID:21037097) UniProt PMID:21037097 NCBI chr12:3,227,790...3,236,161 JBrowse link
G FCN1 ficolin 1 enables IEA Ensembl GO_REF:0000107 Ensembl chr12:3,231,325...3,236,174 JBrowse link
G IFIH1 interferon induced with helicase C domain 1 enables ISO (PMID:21217758), (PMID:23273991) UniProt PMID:21217758 PMID:23273991 NCBI chr10:47,676,799...47,732,310
Ensembl chr10:47,676,920...47,732,264 		JBrowse link
G LOC103227720 twinfilin-2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:13,581,102...13,598,830
Ensembl chr22:13,589,034...13,598,752
Ensembl chr22:13,589,034...13,598,752 		JBrowse link
G LOC103234962 caspase recruitment domain-containing protein 8 enables ISO (PMID:33542150) UniProt PMID:33542150 NCBI chr 6:41,446,890...41,500,098 JBrowse link
G NLRP1 NLR family pyrin domain containing 1 enables ISO (PMID:33243852) UniProt PMID:33243852 NCBI chr16:4,930,643...4,983,378 JBrowse link
G NLRP6 NLR family pyrin domain containing 6 enables ISO (MGI:6833928|PMID:34678144)
(PMID:31932628), (PMID:33377178), (PMID:34678144)		 UniProt PMID:31932628 PMID:33377178 PMID:34678144 MGI:6833928 NCBI chr 1:92,213...99,919 JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr21:27,907,628...27,957,621
Ensembl chr21:27,926,710...27,957,619 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 enables ISO (MGI:5763542|PMID:25429073)
(MGI:6210191|PMID:27007849), (PMID:18261938)
(PMID:22033934)
(PMID:12871942), (PMID:17355968), (PMID:22857257), (PMID:23300079), (PMID:27748583), (PMID:31649195), (PMID:33942347)		 UniProt
MGI		 PMID:12871942 PMID:17355968 PMID:18261938 PMID:22033934 PMID:22857257 More... MGI:5763542 MGI:6210191 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499 		JBrowse link
G RIGI RNA sensor RIG-I enables ISO (PMID:19576794), (PMID:25119032), (PMID:28469175), (PMID:35263596) UniProt PMID:19576794 PMID:25119032 PMID:28469175 PMID:35263596 NCBI chr12:47,729,040...47,800,995
Ensembl chr12:47,729,076...47,799,570 		JBrowse link
G TLR2 toll like receptor 2 enables ISO (PMID:10384090)
(PMID:22033934)		 UniProt
MGI		 PMID:10384090 PMID:22033934 NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795 		JBrowse link
G TLR3 toll like receptor 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232 		JBrowse link
G TLR5 toll like receptor 5 enables ISO (PMID:14625549), (PMID:17128265) UniProt PMID:14625549 PMID:17128265 NCBI chr25:6,418,895...6,440,433
Ensembl chr25:6,437,638...6,440,211 		JBrowse link
G TLR7 toll like receptor 7 enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:11,348,520...11,372,132 JBrowse link
G TLR8 toll like receptor 8 enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:11,387,933...11,405,056
Ensembl chr  X:11,400,907...11,404,029 		JBrowse link
G TRIM5 tripartite motif containing 5 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:61,040,908...61,067,815
Ensembl chr 1:61,040,928...61,069,356 		JBrowse link
(1->3)-beta-D-glucan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A enables ISO (PMID:12719478) MGI PMID:12719478 NCBI chr11:9,989,520...10,007,442
Ensembl chr11:9,995,203...10,006,746 		JBrowse link
lipopolysaccharide immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule enables ISO (PMID:15294986) AgBase PMID:15294986 NCBI chr23:43,264,917...43,266,825
Ensembl chr23:43,264,336...43,266,993 		JBrowse link
G LY96 lymphocyte antigen 96 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:69,591,885...69,629,939
Ensembl chr 8:69,591,941...69,630,274 		JBrowse link
G PTAFR platelet activating factor receptor enables IEA Ensembl GO_REF:0000107 NCBI chr20:104,627,591...104,658,840
Ensembl chr20:104,657,179...104,658,207 		JBrowse link
G SCARB1 scavenger receptor class B member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr11:120,134,485...120,223,512
Ensembl chr11:120,134,874...120,216,904 		JBrowse link
G TLR4 toll like receptor 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
lipoteichoic acid immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule (CD36 blood group) enables IEA Ensembl GO_REF:0000107 NCBI chr21:68,214,875...68,309,336
Ensembl chr21:68,216,201...68,268,669 		JBrowse link
peptidoglycan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGLYRP1 peptidoglycan recognition protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:39,474,077...39,478,635
Ensembl chr 6:39,474,170...39,477,914 		JBrowse link
G PGLYRP2 peptidoglycan recognition protein 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:14,072,310...14,084,014
Ensembl chr 6:14,072,423...14,082,798 		JBrowse link
G PGLYRP3 peptidoglycan recognition protein 3 enables ISO (PMID:11461926) UniProt PMID:11461926 NCBI chr20:10,445,996...10,459,908
Ensembl chr20:10,446,660...10,459,478 		JBrowse link
G PGLYRP4 peptidoglycan recognition protein 4 enables ISO (PMID:11461926) UniProt PMID:11461926 NCBI chr20:10,406,242...10,422,989
Ensembl chr20:10,405,138...10,422,625 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 18111
    molecular transducer activity 1259
      signaling receptor activity 1259
        pattern recognition receptor activity 35
          lipoarabinomannan immune receptor activity 0
          lipopolysaccharide immune receptor activity 5
          lipoteichoic acid immune receptor activity 1
          peptidoglycan immune receptor activity 4
          polysaccharide immune receptor activity + 1
paths to the root