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ONTOLOGY REPORT - ANNOTATIONS


Term:pattern recognition receptor activity
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Accession:GO:0038187 term browser browse the term
Definition:Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.
Synonyms:exact_synonym: PRR;   PRR activity
 narrow_synonym: MAMP receptor activity;   PAMP receptor activity;   microbe-associated molecular pattern receptor activity;   pathogen associated molecular pattern receptor activity
 related_synonym: macrophage receptor activity;   signaling pattern recognition receptor activity
 alt_id: GO:0008329
 xref: Wikipedia:Pattern_recognition_receptor



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pattern recognition receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A enables IEA Ensembl GO_REF:0000107 NCBI chr27:35,852,685...35,885,673
Ensembl chr27:35,853,099...36,007,157
JBrowse link
G CLEC7A C-type lectin domain containing 7A enables IEA Ensembl GO_REF:0000107 NCBI chr27:35,896,421...35,920,649
Ensembl chr27:35,853,099...36,007,157
JBrowse link
G COLEC12 collectin subfamily member 12 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:67,192,191...67,373,524
Ensembl chr 7:67,193,626...67,372,755
JBrowse link
G DHX16 DEAH-box helicase 16 enables IEA Ensembl GO_REF:0000107 NCBI chr12:460,669...478,026
Ensembl chr12:460,713...478,001
JBrowse link
G DMBT1 deleted in malignant brain tumors 1 enables ISO (PMID:19189310) UniProt PMID:19189310 NCBI chr28:32,198,250...32,286,517
Ensembl chr28:32,219,448...32,286,532
JBrowse link
G FCN2 ficolin 2 enables ISO (PMID:21037097) UniProt PMID:21037097 NCBI chr 9:50,868,942...50,876,001
Ensembl chr 9:50,868,973...50,875,792
JBrowse link
G IFIH1 interferon induced with helicase C domain 1 enables IEA Ensembl GO_REF:0000107 NCBI chr36:7,668,925...7,727,040
Ensembl chr36:7,649,727...8,261,048
JBrowse link
G LOC119876002 caspase recruitment domain-containing protein 8-like enables IEA Ensembl GO_REF:0000107
G LOC491519 caspase recruitment domain family, member 8 enables ISO (PMID:33542150) UniProt PMID:33542150 NCBI chr 1:107,994,215...108,025,875 JBrowse link
G LOC611536 C-type lectin domain family 4 member D enables IEA Ensembl GO_REF:0000107 NCBI chr27:37,520,289...37,559,920
Ensembl chr27:37,551,064...37,558,847
JBrowse link
G LOC611538 C-type lectin domain family 4 member E enables IEA Ensembl GO_REF:0000107 NCBI chr27:37,561,445...37,568,652
Ensembl chr27:37,563,038...37,568,463
JBrowse link
G NLRP1 NLR family pyrin domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:31,264,554...31,299,538
Ensembl chr 5:31,266,621...31,299,304
JBrowse link
G NLRP6 NLR family pyrin domain containing 6 enables IEA Ensembl GO_REF:0000107 NCBI chr18:25,433,481...25,440,703
Ensembl chr18:25,433,698...25,440,740
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr14:43,162,671...43,226,948
Ensembl chr14:43,163,571...43,227,103
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232
JBrowse link
G RIGI RNA sensor RIG-I enables ISO (PMID:19576794), (PMID:25119032), (PMID:28469175), (PMID:35263596) UniProt PMID:19576794 PMID:25119032 PMID:28469175 PMID:35263596 NCBI chr11:49,764,252...49,799,626
Ensembl chr11:49,764,267...49,799,527
JBrowse link
G TLR2 toll like receptor 2 enables IEA Ensembl GO_REF:0000107 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
JBrowse link
G TLR2 toll like receptor 2 enables IEA Ensembl GO_REF:0000107
G TLR3 toll like receptor 3 enables IEA Ensembl GO_REF:0000107 NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247
JBrowse link
G TLR5 toll like receptor 5 enables ISO (PMID:14625549), (PMID:17128265) UniProt PMID:14625549 PMID:17128265 NCBI chr38:23,700,323...23,705,628
Ensembl chr38:23,702,033...23,705,314
JBrowse link
G TLR9 toll like receptor 9 enables ISS
IBA
IEA
UniProt
GO_Central
Ensembl
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114
JBrowse link
(1->3)-beta-D-glucan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A enables ISO (PMID:12719478) MGI PMID:12719478 NCBI chr27:35,852,685...35,885,673
Ensembl chr27:35,853,099...36,007,157
JBrowse link
lipopolysaccharide immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule enables IEA Ensembl GO_REF:0000107 NCBI chr 2:35,790,505...35,792,967 JBrowse link
G LY96 lymphocyte antigen 96 enables IEA Ensembl GO_REF:0000107 NCBI chr29:22,493,757...22,515,147
Ensembl chr29:22,493,896...22,515,117
JBrowse link
G PTAFR platelet activating factor receptor enables IEA Ensembl GO_REF:0000107 NCBI chr 2:72,225,386...72,256,353
Ensembl chr 2:72,225,386...72,256,352
JBrowse link
G SCARB1 scavenger receptor class B member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr26:5,035,797...5,122,383
Ensembl chr26:5,049,407...5,121,468
JBrowse link
G TLR4 toll like receptor 4 enables IEA Ensembl GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165
JBrowse link
lipoteichoic acid immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule (CD36 blood group) enables IEA Ensembl GO_REF:0000107 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639
JBrowse link
peptidoglycan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGLYRP1 peptidoglycan recognition protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:109,614,404...109,618,242
Ensembl chr 1:109,614,437...109,618,242
JBrowse link
G PGLYRP2 peptidoglycan recognition protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr20:46,724,906...46,730,227
Ensembl chr20:46,726,224...46,730,321
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18552
    molecular transducer activity 1790
      signaling receptor activity 1790
        pattern recognition receptor activity 29
          lipoarabinomannan immune receptor activity 0
          lipopolysaccharide immune receptor activity 5
          lipoteichoic acid immune receptor activity 1
          peptidoglycan immune receptor activity 2
          polysaccharide immune receptor activity + 1
paths to the root