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ONTOLOGY REPORT - ANNOTATIONS

Term:pattern recognition receptor activity
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Accession:GO:0038187 term browser browse the term
Definition:Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.
Synonyms:exact_synonym: PRR;   PRR activity
 narrow_synonym: MAMP receptor activity;   PAMP receptor activity;   microbe-associated molecular pattern receptor activity;   pathogen associated molecular pattern receptor activity
 related_synonym: macrophage receptor activity;   signaling pattern recognition receptor activity
 alt_id: GO:0008329
 xref: Wikipedia:Pattern_recognition_receptor


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pattern recognition receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIM2 absent in melanoma 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:134,413,232...134,540,344
Ensembl chr 1:138,210,946...138,221,753 		JBrowse link
G CARD8 caspase recruitment domain family member 8 enables IEA Ensembl GO_REF:0000107 NCBI chr19:45,204,735...45,256,481
Ensembl chr19:53,798,967...53,850,328 		JBrowse link
G CLEC4D C-type lectin domain family 4 member D enables IEA Ensembl GO_REF:0000107 NCBI chr12:8,599,654...8,608,494
Ensembl chr12:8,814,680...8,823,484 		JBrowse link
G CLEC4E C-type lectin domain family 4 member E enables ISO (PMID:24101491)
(MGI:4415080|PMID:20008526)
(MGI:3796003|PMID:18490740)		 UniProt PMID:18490740 PMID:20008526 PMID:24101491 MGI:3796003 MGI:4415080 NCBI chr12:8,620,618...8,627,610 JBrowse link
G CLEC6A C-type lectin domain containing 6A enables IEA Ensembl GO_REF:0000107 NCBI chr12:8,537,766...8,560,736
Ensembl chr12:8,752,778...8,775,738 		JBrowse link
G CLEC7A C-type lectin domain containing 7A enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:10,161,780...10,174,943
Ensembl chr12:10,410,384...10,425,452 		JBrowse link
G COLEC12 collectin subfamily member 12 enables IEA Ensembl GO_REF:0000107 NCBI chr18:13,819,575...14,001,383
Ensembl chr18:17,461,678...17,640,721 		JBrowse link
G DHX16 DEAH-box helicase 16 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:30,397,774...30,417,758
Ensembl chr 6:31,267,669...31,287,435 		JBrowse link
G DMBT1 deleted in malignant brain tumors 1 enables ISO (PMID:19189310) UniProt PMID:19189310 NCBI chr10:119,129,440...119,200,232
Ensembl chr10:122,540,855...123,474,497 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 enables IEA Ensembl GO_REF:0000107 NCBI chr2B:49,560,620...49,612,086
Ensembl chr2B:166,928,994...166,980,170 		JBrowse link
G LOC100986336 twinfilin-2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:52,163,388...52,181,473
Ensembl chr 3:53,400,191...53,410,743
Ensembl chr 3:53,400,191...53,410,743 		JBrowse link
G LOC100994951 ficolin-1 enables ISO (PMID:21037097) UniProt PMID:21037097 NCBI chr 9:106,039,315...106,047,648
Ensembl chr 9:135,040,310...135,049,111 		JBrowse link
G NLRP1 NLR family pyrin domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr17:5,562,129...5,667,765
Ensembl chr17:5,542,007...5,623,091 		JBrowse link
G NLRP6 NLR family pyrin domain containing 6 enables IEA Ensembl GO_REF:0000107 NCBI chr11:274,904...281,590
Ensembl chr11:319,082...325,888 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:31,060,245...31,109,012
Ensembl chr 7:31,182,275...31,208,742 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 enables IEA Ensembl GO_REF:0000107 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773 		JBrowse link
G RIGI RNA sensor RIG-I enables IEA Ensembl GO_REF:0000107 NCBI chr 9:32,230,012...32,302,159
Ensembl chr 9:33,040,000...33,110,557 		JBrowse link
G TLR2 toll like receptor 2 enables ISO (PMID:10384090)
(PMID:22033934)		 UniProt
MGI		 PMID:10384090 PMID:22033934 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331 		JBrowse link
G TLR3 toll like receptor 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:178,238,352...178,256,264
Ensembl chr 4:190,446,487...190,462,728 		JBrowse link
G TLR5 toll like receptor 5 enables ISO (PMID:14625549), (PMID:17128265) UniProt PMID:14625549 PMID:17128265 NCBI chr 1:198,787,046...198,819,537
Ensembl chr 1:203,798,767...203,801,343 		JBrowse link
G TLR7 toll like receptor 7 enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:5,479,247...5,504,810
Ensembl chr  X:12,767,981...12,790,517 		JBrowse link
G TLR8 toll like receptor 8 enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:5,518,742...5,535,304 JBrowse link
G TRIM5 tripartite motif containing 5 enables ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:5,798,336...5,819,876
Ensembl chr11:5,479,033...5,500,758 		JBrowse link
(1->3)-beta-D-glucan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A enables ISO (PMID:12719478) MGI PMID:12719478 NCBI chr12:10,161,780...10,174,943
Ensembl chr12:10,410,384...10,425,452 		JBrowse link
lipopolysaccharide immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule enables IEA Ensembl GO_REF:0000107 NCBI chr 5:135,996,265...135,997,909
Ensembl chr 5:142,113,082...142,118,966 		JBrowse link
G LY96 lymphocyte antigen 96 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:70,525,058...70,567,839
Ensembl chr 8:72,169,986...72,207,372 		JBrowse link
G PTAFR platelet activating factor receptor enables IEA Ensembl GO_REF:0000107 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861 		JBrowse link
G SCARB1 scavenger receptor class B member 1 enables ISO (PMID:12651854) BHF-UCL PMID:12651854 NCBI chr12:122,293,803...122,455,314
Ensembl chr12:126,659,532...126,694,767 		JBrowse link
G TLR4 toll like receptor 4 enables IEA
ISS		 Ensembl
TreeGrafter
UniProt		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
lipoteichoic acid immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule (CD36 blood group) enables IEA Ensembl GO_REF:0000107 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865 		JBrowse link
peptidoglycan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGLYRP1 peptidoglycan recognition protein 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:43,033,080...43,037,726
Ensembl chr19:51,569,275...51,573,764 		JBrowse link
G PGLYRP2 peptidoglycan recognition protein 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:14,999,893...15,012,376
Ensembl chr19:15,986,090...15,997,726 		JBrowse link
G PGLYRP3 peptidoglycan recognition protein 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:128,642,034...128,656,082
Ensembl chr 1:132,270,957...132,283,860 		JBrowse link
G PGLYRP4 peptidoglycan recognition protein 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:128,681,726...128,700,275
Ensembl chr 1:132,310,256...132,329,013 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17714
    molecular transducer activity 1296
      signaling receptor activity 1296
        pattern recognition receptor activity 33
          lipoarabinomannan immune receptor activity 0
          lipopolysaccharide immune receptor activity 5
          lipoteichoic acid immune receptor activity 1
          peptidoglycan immune receptor activity 4
          polysaccharide immune receptor activity + 1
paths to the root