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ONTOLOGY REPORT - ANNOTATIONS

Term:pattern recognition receptor activity
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Accession:GO:0038187 term browser browse the term
Definition:Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.
Synonyms:exact_synonym: PRR;   PRR activity
 narrow_synonym: MAMP receptor activity;   PAMP receptor activity;   microbe-associated molecular pattern receptor activity;   pathogen associated molecular pattern receptor activity
 related_synonym: macrophage receptor activity;   signaling pattern recognition receptor activity
 alt_id: GO:0008329
 xref: Wikipedia:Pattern_recognition_receptor


show annotations for term's descendants           Sort by:
pattern recognition receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 enables ISO (PMID:26197926)
(PMID:23567559), (PMID:27846608), (PMID:32350463)		 RGD PMID:23567559 PMID:26197926 PMID:27846608 PMID:32350463 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975 		JBrowse link
G Clec4a C-type lectin domain family 4, member A enables ISO (MGI:5300086|PMID:22041900)
(PMID:22041900)		 RGD PMID:22041900 MGI:5300086 NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402 		JBrowse link
G Clec4d C-type lectin domain family 4, member D enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23911656)		 UniProt
Ensembl
RGD		 PMID:23911656 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848 		JBrowse link
G Clec4e C-type lectin domain family 4, member E enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:18490740), (PMID:20008526)
(MGI:3796003|PMID:18490740), (MGI:4415080|PMID:20008526)
GO_REF:0000107
(PMID:24101491)		 UniProt
RGD
Ensembl		 PMID:18490740 PMID:20008526 PMID:24101491 GO_REF:0000024 GO_REF:0000107 MGI:3796003 MGI:4415080 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767 		JBrowse link
G Clec6a-ps1 C-type lectin domain family 6, member A, pseudogene 1 enables ISO (PMID:23911656) RGD PMID:23911656 NCBI chr 4:156,539,408...156,559,032
Ensembl chr 4:156,539,408...156,558,605
Ensembl chr 4:156,539,408...156,558,605 		JBrowse link
G Clec7a C-type lectin domain containing 7A enables ISO
IBA		 (PMID:11567029)
(PMID:15213161), (PMID:17159984), (PMID:19136564)
GO_REF:0000033
(MGI:3045647|PMID:15213161), (MGI:3694815|PMID:17159984), (MGI:3844414|PMID:19136564)		 RGD
GO_Central		 PMID:11567029 PMID:15213161 PMID:17159984 PMID:19136564 GO_REF:0000033 MGI:3045647 MGI:3694815 MGI:3844414 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Colec12 collectin sub-family member 12 enables ISO
ISS		 (PMID:11564734)
GO_REF:0000024		 RGD
UniProt		 PMID:11564734 GO_REF:0000024 NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618 		JBrowse link
G Dhx16 DEAH-box helicase 16 enables ISO (PMID:35263596) RGD PMID:35263596 NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 enables ISO (PMID:19189310) RGD PMID:19189310 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478 		JBrowse link
G Fcna ficolin A enables ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105 		JBrowse link
G Fcnb ficolin B enables ISO (PMID:21037097) RGD PMID:21037097 NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 enables ISO (PMID:21217758), (PMID:23273991) RGD PMID:21217758 PMID:23273991 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A enables ISO (PMID:33243852) RGD PMID:33243852 NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:34678144)
GO_REF:0000107
(MGI:6833928|PMID:34678144)
(PMID:31932628), (PMID:33377178), (PMID:34678144)		 UniProt
RGD
Ensembl		 PMID:31932628 PMID:33377178 PMID:34678144 GO_REF:0000024 GO_REF:0000107 MGI:6833928 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 enables ISO (PMID:11058605), (PMID:12791997), (PMID:12796777), (PMID:12871942), (PMID:23300079), (PMID:31649195), (PMID:33942347)
(MGI:6210191|PMID:27007849), (PMID:18261938)		 RGD PMID:11058605 PMID:12791997 PMID:12796777 PMID:12871942 PMID:18261938 More... MGI:6210191 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 enables ISO (PMID:12871942), (PMID:17355968), (PMID:22857257), (PMID:23300079), (PMID:27748583), (PMID:31649195), (PMID:33942347)
MGI:3529594 (PMID:18261938), (PMID:22033934), (PMID:25429073), (PMID:27007849)
MGI:3529594 (MGI:5763542|PMID:25429073), (MGI:6210191|PMID:27007849), (PMID:18261938), (PMID:22033934)		 RGD PMID:12871942 PMID:17355968 PMID:18261938 PMID:22033934 PMID:22857257 More... MGI:5763542 MGI:6210191 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Rig1 RNA sensor RIG-1 enables ISO (PMID:19576794), (PMID:25119032), (PMID:35263596)
(PMID:28469175)		 RGD PMID:19576794 PMID:25119032 PMID:28469175 PMID:35263596 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Tlr2 toll-like receptor 2 enables ISO (PMID:10384090)
MGI:2674036 (PMID:22033934)		 RGD PMID:10384090 PMID:22033934 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 enables ISO (PMID:16720699), (PMID:17128265)
MGI:1346877|MGI:3690535 (PMID:12855817), (PMID:16260493)		 RGD PMID:12855817 PMID:16260493 PMID:16720699 PMID:17128265 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr5 toll-like receptor 5 enables ISO (PMID:14625549), (PMID:17128265) RGD PMID:14625549 PMID:17128265 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tlr7 toll-like receptor 7 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Tlr8 toll-like receptor 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
G Tlr9 toll-like receptor 9 enables ISO
IBA		 (PMID:14716310), (PMID:17128265)
GO_REF:0000033		 RGD
GO_Central		 PMID:14716310 PMID:17128265 GO_REF:0000033 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Trim5 tripartite motif-containing 5 enables ISO (PMID:21512573) RGD PMID:21512573 NCBI chr 1:158,720,407...158,737,393
Ensembl chr 1:158,720,410...158,814,012 		JBrowse link
(1->3)-beta-D-glucan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A enables ISO (PMID:12719478) RGD PMID:12719478 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
lipopolysaccharide immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule enables ISO (PMID:15294986) RGD PMID:15294986 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Ly96 lymphocyte antigen 96 enables ISO (PMID:19252480) RGD PMID:19252480 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386 		JBrowse link
G Ptafr platelet-activating factor receptor enables ISO (PMID:9013981) RGD PMID:9013981 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 enables ISO
IEA		 (PMID:12651854)
GO_REF:0000107		 RGD
Ensembl		 PMID:12651854 GO_REF:0000107 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Tlr4 toll-like receptor 4 enables IEA
ISO
IBA
ISS		 GO_REF:0000107
(PMID:16260493), (PMID:18261938), (PMID:28098138)
(MGI:5913054|PMID:28098138), (PMID:16260493), (PMID:18261938)
GO_REF:0000033
GO_REF:0000024
(PMID:19252480)		 Ensembl
RGD
GO_Central
UniProt		 PMID:16260493 PMID:18261938 PMID:19252480 PMID:28098138 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5913054 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
lipoteichoic acid immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule enables IEA
ISO		 GO_REF:0000107
MGI:2447190 (PMID:16061696)		 Ensembl
RGD		 PMID:16061696 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
peptidoglycan immune receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pglyrp1 peptidoglycan recognition protein 1 enables TAS
IBA
ISO		 GO_REF:0000033
(PMID:11461926)		 GO_Central
RGD		 PMID:11461926 PMID:11145837 GO_REF:0000033, RGD:724610 NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001 		JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 enables ISO (PMID:11461926) RGD PMID:11461926 NCBI chr 7:11,418,674...11,432,162
Ensembl chr 7:11,418,880...11,427,773 		JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 enables ISO (PMID:11461926) RGD PMID:11461926 NCBI chr 2:177,479,693...177,490,769
Ensembl chr 2:177,477,407...177,490,736
Ensembl chr 2:177,477,407...177,490,736 		JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 enables ISO (PMID:11461926) RGD PMID:11461926 NCBI chr 2:176,202,654...176,322,859
Ensembl chr 2:176,218,519...176,242,251 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20736
    molecular transducer activity 2601
      signaling receptor activity 2601
        pattern recognition receptor activity 34
          lipoarabinomannan immune receptor activity 0
          lipopolysaccharide immune receptor activity 5
          lipoteichoic acid immune receptor activity 1
          peptidoglycan immune receptor activity 4
          polysaccharide immune receptor activity + 1
paths to the root