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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:complement component C5a signaling pathway
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Accession:GO:0038178 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by a C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.
Synonyms:exact_synonym: complement component C5a-induced signaling pathway


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complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in ISO (PMID:10571060) RGD PMID:10571060 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      signal transduction 7209
        G protein-coupled receptor signaling pathway 2434
          complement component C5a signaling pathway 3
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of immune system process 1705
          positive regulation of immune system process 1186
            positive regulation of immune response 804
              activation of immune response 572
                immune response-activating signaling pathway 485
                  immune response-activating cell surface receptor signaling pathway 304
                    complement receptor mediated signaling pathway 15
                      complement component C5a signaling pathway 3
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