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ONTOLOGY REPORT - ANNOTATIONS

Term:death receptor agonist activity
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Accession:GO:0038177 term browser browse the term
Definition:Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor.
Synonyms:exact_synonym: death receptor activator activity


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death receptor agonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eda ectodysplasin-A enables ISO (PMID:27144394) RGD PMID:27144394 NCBI chr  X:69,118,577...69,520,274
Ensembl chr  X:65,078,673...65,480,172 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A enables ISO (PMID:26183779) RGD PMID:26183779 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B enables ISO (PMID:26183779) RGD PMID:26183779 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ngf nerve growth factor enables ISO UniProtKB:P08138 (PMID:11927634) RGD PMID:11927634 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Tnf tumor necrosis factor enables ISO
IEA		 (PMID:10748004)
GO_REF:0000107
(PMID:14985352)		 RGD
Ensembl		 PMID:10748004 PMID:14985352 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
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Term Annotations click to browse term
  molecular_function 21100
    binding 18098
      protein binding 14913
        signaling receptor binding 1619
          receptor ligand activity 527
            death receptor agonist activity 5
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