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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:cannabinoid signaling pathway
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Accession:GO:0038171 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by a cannabinoid binding to its receptor on the cell surface, and ending with the regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.
Synonyms:exact_synonym: cannabinoid receptor signaling pathway;   cannabinoid-activated signaling pathway;   cannabinoid-mediated signaling pathway


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cannabinoid signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 involved_in IDA
ISO		 PMID:17895407
(MGI:5819353|PMID:16540577)
(PMID:17895407)		 RGD PMID:16540577 PMID:17895407 PMID:17895407 MGI:5819353, RGD:13461761 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Gpr55 G protein-coupled receptor 55 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613 		JBrowse link
endocannabinoid signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15b arachidonate 15-lipoxygenase, type B involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:11956198)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:11956198 GO_REF:0000024 GO_REF:0000107 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812 		JBrowse link
G Dagla diacylglycerol lipase, alpha acts_upstream_of_or_within ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232 		JBrowse link
regulation of endocannabinoid signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase acts_upstream_of_or_within ISO (PMID:20657592) RGD PMID:20657592 NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in ISS
ISO		 GO_REF:0000024
(MGI:5494205|PMID:23502535)		 UniProt
RGD		 PMID:23502535 GO_REF:0000024 MGI:5494205 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Mgll monoglyceride lipase involved_in ISO (MGI:4836780|PMID:20729846) RGD PMID:20729846 MGI:4836780 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      signal transduction 7163
        G protein-coupled receptor signaling pathway 2419
          cannabinoid signaling pathway 8
            endocannabinoid signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 20292
    biological regulation 13633
      regulation of biological process 13220
        signaling 7729
          signal transduction 7163
            G protein-coupled receptor signaling pathway 2419
              cannabinoid signaling pathway 8
                endocannabinoid signaling pathway + 5
paths to the root