Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:sequestering of TGFbeta from receptor via TGFbeta binding
go back to main search page
Accession:GO:0038105 term browser browse the term
Definition:Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor.
Comment:This term is for annotation of gene products that bind to TGFbeta. For gene products that tether the TGFbeta-containing latency complex to the extracellular matrix, but do not necessarily bind TGF-beta directly, consider instead annotating to 'sequestering of TGFbeta in extracellular matrix ; GO:0035583'.
Synonyms:broad_synonym: extracellular sequestering of TGFbeta;   extracellular sequestering of transforming growth factor-beta


show annotations for term's descendants           Sort by:
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    cellular process 16838
      signal transduction 6973
        negative regulation of signal transduction 1436
          extracellular negative regulation of signal transduction 11
            sequestering of extracellular ligand from receptor 10
              sequestering of TGFbeta from receptor via TGFbeta binding 0
Path 2
Term Annotations click to browse term
  biological_process 17799
    biological regulation 12896
      regulation of biological process 12533
        signaling 7515
          signal transduction 6973
            regulation of signal transduction 3115
              extracellular regulation of signal transduction 11
                extracellular negative regulation of signal transduction 11
                  sequestering of extracellular ligand from receptor 10
                    sequestering of TGFbeta from receptor via TGFbeta binding 0
paths to the root