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ONTOLOGY REPORT - ANNOTATIONS


Term:sequestering of TGFbeta from receptor via TGFbeta binding
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Accession:GO:0038105 term browser browse the term
Definition:Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor.
Comment:This term is for annotation of gene products that bind to TGFbeta. For gene products that tether the TGFbeta-containing latency complex to the extracellular matrix, but do not necessarily bind TGF-beta directly, consider instead annotating to 'sequestering of TGFbeta in extracellular matrix ; GO:0035583'.
Synonyms:broad_synonym: extracellular sequestering of TGFbeta;   extracellular sequestering of transforming growth factor-beta


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Path 1
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      signal transduction 3950
        negative regulation of signal transduction 1223
          extracellular negative regulation of signal transduction 10
            sequestering of extracellular ligand from receptor 9
              sequestering of TGFbeta from receptor via TGFbeta binding 0
Path 2
Term Annotations click to browse term
  biological_process 12346
    biological regulation 8880
      regulation of biological process 8618
        signaling 4445
          signal transduction 3950
            regulation of signal transduction 2638
              extracellular regulation of signal transduction 10
                extracellular negative regulation of signal transduction 10
                  sequestering of extracellular ligand from receptor 9
                    sequestering of TGFbeta from receptor via TGFbeta binding 0
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