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ONTOLOGY REPORT - ANNOTATIONS


Term:Fc-epsilon receptor signaling pathway
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Accession:GO:0038095 term browser browse the term
Definition:The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
Synonyms:exact_synonym: Fc-epsilon receptor signalling pathway



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Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1A Fc epsilon receptor Ia involved_in IEA GOC GO_REF:0000108 NCBI chr 1:134,655,230...134,660,961
Ensembl chr 1:138,439,921...138,458,258
JBrowse link
G FCER1G Fc epsilon receptor Ig involved_in IEA GOC GO_REF:0000108 NCBI chr 1:136,627,672...136,631,696
Ensembl chr 1:140,539,555...140,544,810
JBrowse link
G FCER2 Fc epsilon receptor II involved_in IEA GOC GO_REF:0000108 NCBI chr19:6,978,116...6,989,986
Ensembl chr19:7,834,106...7,844,924
JBrowse link
G FER FER tyrosine kinase involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 5:104,099,620...104,548,077
Ensembl chr 5:109,964,823...110,350,576
JBrowse link
G LOC100981392 leukocyte immunoglobulin-like receptor subfamily A member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:51,287,944...51,294,118
Ensembl chr19:60,128,447...60,134,248
JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR4A3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chr 9:70,907,056...70,950,221 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16309
    cellular process 15385
      signal transduction 5405
        cell surface receptor signaling pathway 2599
          immune response-regulating cell surface receptor signaling pathway 291
            Fc receptor signaling pathway 21
              Fc-epsilon receptor signaling pathway 6
                positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 16309
    biological regulation 11305
      regulation of biological process 10967
        regulation of cellular process 10489
          signal transduction 5405
            immune response-regulating signaling pathway 469
              immune response-regulating cell surface receptor signaling pathway 291
                Fc receptor signaling pathway 21
                  Fc-epsilon receptor signaling pathway 6
                    positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway 1
paths to the root