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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:Fc-epsilon receptor signaling pathway
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Accession:GO:0038095 term browser browse the term
Definition:The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
Synonyms:exact_synonym: Fc-epsilon receptor signalling pathway


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Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc epsilon receptor Ia involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fcer1g Fc epsilon receptor Ig involved_in ISO
IEA		 (PMID:16735691)
GO_REF:0000108		 RGD
GOC		 PMID:16735691 GO_REF:0000108 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fcer2 Fc epsilon receptor II involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:1,742,809...1,754,476
Ensembl chr12:1,742,815...1,754,476 		JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921 		JBrowse link
G Fer FER tyrosine kinase involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(MGI:2385502|PMID:12192036)		 UniProt
GO_Central
TreeGrafter
RGD		 PMID:12192036 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:2385502 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310 		JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5586645|PMID:24586680)		 UniProt
RGD		 PMID:24586680 GO_REF:0000024 MGI:5586645 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      signal transduction 7163
        cell surface receptor signaling pathway 2879
          immune response-regulating cell surface receptor signaling pathway 321
            Fc receptor signaling pathway 24
              Fc-epsilon receptor signaling pathway 7
                positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 20292
    biological regulation 13633
      regulation of biological process 13220
        regulation of cellular process 12685
          signal transduction 7163
            immune response-regulating signaling pathway 500
              immune response-regulating cell surface receptor signaling pathway 321
                Fc receptor signaling pathway 24
                  Fc-epsilon receptor signaling pathway 7
                    positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway 1
paths to the root